Results 11 to 20 of about 34,733 (291)

Hypereosinophilia is a predictive biomarker of immune checkpoint inhibitor-induced hypopituitarism in patients with renal cell carcinoma

BMC Endocrine Disorders, 2022
Background This study aimed to evaluate whether hypereosinophilia is a clinical biomarker of immune checkpoint inhibitor-induced hypopituitarism in patients with renal cell carcinoma treated with nivolumab plus ipilimumab.
Hodaka Yamada, Satoshi Washino, Daisuke Suzuki, Rika Saikawa, Shiori Tonezawa, Rie Hagiwara, Shunsuke Funazaki, Masashi Yoshida, Tsuzumi Konishi, Kimitoshi Saito, Tomoaki Miyagawa, Kazuo Hara   +11 more
doaj   +2 more sources

Management of hypopituitarism: a perspective from the Brazilian Society of Endocrinology and Metabolism

Archives of Endocrinology and Metabolism, 2021
Hypopituitarism is a disorder characterized by insufficient secretion of one or more pituitary hormones. New etiologies of hypopituitarism have been recently described, including head trauma, cerebral hemorrhage, and drug-induced hypophysitis.
Heraldo Mendes Garmes, César Luiz Boguszewski, Paulo Augusto Carvalho Miranda, Manoel Ricardo Alves Martins, Silvia Regina Correa da Silva, Julio Zaki Abucham Filho, Nina Rosa de Castro Musolino, Lucio Vilar, Luiz Henrique Corrêa Portari, Mônica Roberto Gadelha, Leandro Kasuki, Luciana Ansaneli Naves, Mauro Antônio Czepielewski, Tobias Skrebsky de Almeida, Felipe Henning Gaia Duarte, Andrea Glezer, Marcello Delano Bronstein   +16 more
doaj   +2 more sources

Evidence That the Etiology of Congenital Hypopituitarism Has a Major Genetic Component but Is Infrequently Monogenic

Frontiers in Genetics, 2021
PurposeCongenital hypopituitarism usually occurs sporadically. In most patients, the etiology remains unknown.MethodsWe studied 13 children with sporadic congenital hypopituitarism. Children with non-endocrine, non-familial idiopathic short stature (NFSS)
Youn Hee Jee, Mariam Gangat, Olga Yeliosof, Adrian G. Temnycky, Selena Vanapruks, Philip Whalen, Evgenia Gourgari, Cortney Bleach, Christine H. Yu, Ian Marshall, Jack A. Yanovski, Kathleen Link, Svetlana Ten, Jeffrey Baron, Sally Radovick   +14 more
doaj   +2 more sources

Genetic causes of hypopituitarism

Archives of Medical Science, 2019
Hypopituitarism in neonates is rare, but has life-threatening complications if untreated. This review describes the features of hypopituitarism and the evidence for which infants in whom a genetic cause should be suspected.
Katherine Parkin, Ritika Kapoor, Ravindra Bhat, Anne Greenough   +3 more
doaj   +2 more sources

Genetic diagnosis of congenital hypopituitarism by a target gene panel: novel pathogenic variants in GLI2, OTX2 and GHRHR

Endocrine Connections, 2019
Aim: Congenital hypopituitarism has an incidence of 1:3500–10,000 births and is defined by the impaired production of pituitary hormones. Early diagnosis has an impact on management and genetic counselling.
Marilena Nakaguma, Fernanda A Correa, Lucas S Santana, Anna F F Benedetti, Ricardo V Perez, Martha K P Huayllas, Mirta B Miras, Mariana F A Funari, Antonio M Lerario, Berenice B Mendonca, Luciani R S Carvalho, Alexander A L Jorge, Ivo J P Arnhold   +12 more
doaj   +2 more sources

Etiology of Hypopituitarism in Adult Patients: The Experience of a Single Center Database in the Serbian Population

International Journal of Endocrinology, 2017
There are only a few published studies related to the population-based etiology of hypopituitarism. New risks for developing hypopituitarism have been recognized in the last 10 years. Aim.
M. Doknić, S. Pekić, D. Miljić, I. Soldatović, V. Popović, M. Stojanović, M. Petakov   +6 more
doaj   +2 more sources

Hypopituitarism after Orthohantavirus Infection: What is Currently Known?

Viruses, 2019
Several case reports have described hypopituitarism following orthohantavirus infection, mostly following Puumala virus. The pathogenesis of this seemingly rare complication of orthohantavirus infection remains unknown.
Soerajja Bhoelan, Thomas Langerak, Danny Noack, Linda van Schinkel, Els van Nood, Eric C.M. van Gorp, Barry Rockx, Marco Goeijenbier   +7 more
doaj   +2 more sources

Neonatal Hypopituitarism: Approaches to Diagnosis and Treatment

JCRPE, 2019
Hypopituitarism is defined as a decreased release of hypophyseal hormones, which may be caused by disease of the pituitary gland disease or hypothalamus. The clinical findings of neonatal hypopituitarism depend on the causes and on presence and extent of
Selim Kurtoğlu, Ahmet Özdemir, Nihal Hatipoğlu   +2 more
doaj   +2 more sources

Adrenal Crisis Induced by Zoledronic Acid in Two Patients With Hypopituitarism: A Case Report and Literature Review. [PDF]

Case Rep Endocrinol
Adrenal insufficiency (AI) is characterized by inadequate steroid hormone production and is frequently a consequence of hypopituitarism, which is also associated with increased risk of osteoporosis due to deficiencies in growth hormone, gonadotropins, and other pituitary hormones.
AlFaifi AM, AlMistehi WM.
europepmc   +2 more sources

Congenital Hypopituitarism During the Neonatal Period: Epidemiology, Pathogenesis, Therapeutic Options, and Outcome

Frontiers in Pediatrics, 2021
Introduction: Congenital hypopituitarism (CH) is characterized by a deficiency of one or more pituitary hormones. The pituitary gland is a central regulator of growth, metabolism, and reproduction.
Laura Bosch i Ara, H. Katugampola, M. Dattani   +2 more
semanticscholar   +1 more source