Results 21 to 30 of about 34,733 (291)

Decreased mannan-binding lectin level in adults with hypopituitarism; dependence on appropriate hormone replacement therapies

open access: yesFrontiers in Immunology, 2023
BackgroundMannan-binding lectin (MBL) is a main component of the lectin pathway of the complement system. Although there are some studies showing links between endocrine and immune systems, the ones concerning hypopituitarism are limited. The aim of this
Aleksandra E. Matusiak   +5 more
doaj   +1 more source

Hypopituitarism is associated with lower oxytocin concentrations and reduced empathic ability [PDF]

open access: hybridEndocrine, 2017
PurposeCentral diabetes insipidus is characterised by arginine vasopressin deficiency. Oxytocin is structurally related to vasopressin and is synthesised in the same hypothalamic nuclei, thus we hypothesised that patients with acquired central diabetes ...
Katie Daughters   +2 more
openalex   +2 more sources

Traumatic Brain Injury as Frequent Cause of Hypopituitarism and Growth Hormone Deficiency: Epidemiology, Diagnosis, and Treatment

open access: yesFrontiers in Endocrinology, 2021
Traumatic brain injury (TBI)-related hypopituitarism has been recognized as a clinical entity for more than a century, with the first case being reported in 1918. However, during the 20th century hypopituitarism was considered only a rare sequela of TBI.
V. Gasco   +4 more
semanticscholar   +1 more source

Activating mutations in BRAF disrupt the hypothalamo-pituitary axis leading to hypopituitarism in mice and humans

open access: yesNature Communications, 2021
Germline mutations in BRAF and other components of the MAPK pathway are associated with the congenital syndromes collectively known as RASopathies. Here, we report the association of Septo-Optic Dysplasia (SOD) including hypopituitarism and Cardio-Facio ...
Gualtieri A   +24 more
semanticscholar   +1 more source

The Involvement of the GH/IGF-I Axis in Cognitive Functions of Adult Patients and Healthy Subjects [PDF]

open access: yes, 2012
The complexity of hyponatremia as a clinical problem is likely caused by the opposite scenarios that accompany this electrolyte disorder regarding pathophysiology (depletional versus dilutional hyponatremia, high versus low vasopressin levels) and ...
Deijen, J.B., Drent, M.L., Driel, M.I.
core   +7 more sources

Post-Traumatic Hypopituitarism—Who Should Be Screened, When, and How? [PDF]

open access: goldFrontiers in Endocrinology, 2018
Traumatic brain injury (TBI) remains a major, global public health concern. Over the last 15 years, a significant body of evidence has emerged demonstrating that post-traumatic hypopituitarism (PTHP) is a common and clinically significant consequence of ...
Mark Quinn, Amar Agha
openalex   +2 more sources

Lipid profile and response to statin therapy in patients with hypopituitarism

open access: yesArchives of Endocrinology and Metabolism, 2020
Objective: Dyslipidemia is prevalent among patients with hypopituitarism, especially in those with growth hormone (GH) deficiency. This study aimed to evaluate the response to statin therapy among adult patients with dyslipidemia and hypopituitarism ...
Graziela Rissetti   +5 more
doaj   +1 more source

Genetic regulation of pituitary gland development in human and mouse [PDF]

open access: yes, 2009
Normal hypothalamopituitary development is closely related to that of the forebrain and is dependent upon a complex genetic cascade of transcription factors and signaling molecules that may be either intrinsic or extrinsic to the developing Rathke’s ...
Aarskog   +321 more
core   +2 more sources

Cholestasis and hypercalcemia secondary to panhypopituitarism in a newborn

open access: yesThe Turkish Journal of Pediatrics, 2017
Cholestatic hepatitis and hypercalcemia are rare features of hypopituitarism in newborns. So diagnosis of hypopituitarism is frequently delayed.
Fatma Dursun   +2 more
doaj   +1 more source

The role of stereotactic radiosurgery in the multimodal management of growth hormone–secreting pituitary adenomas [PDF]

open access: yes, 2010
Growth hormone (GH)–secreting pituitary adenomas represent a common source of GH excess in patients with acromegaly. Whereas surgical extirpation of the culprit lesion is considered first-line treatment, as many as 19% of patients develop recurrent ...
Liu, Charles Y.   +2 more
core   +1 more source

Home - About - Disclaimer - Privacy