Hypopituitarism and atherosclerosis
In the last decade, retrospective cohort data has provided evidence of premature atherosclerosis in patients with hypopituitarism which may account for the recently observed increased death rate from vascular events in these patients. The exact mechanism(s) for such propensity to atherosclerotic vascular disease is not yet completely clear.
T A, Elhadd, T A, Abdu, R, Clayton
openaire +2 more sources
Background Metastasis to the pituitary gland is an infrequent clinical problem, and the symptoms caused by metastases have been reported in only 2.5–18.2% of the cases.
Ryohei Ono +5 more
doaj +1 more source
Development and validation of a new questionnaire assessing quality of life in adults with hypopituitarism: Adult Hypopituitarism Questionnaire (AHQ). [PDF]
OBJECTIVE: To develop and validate the Adult Hypopituitarism Questionnaire (AHQ) as a disease-specific, self-administered questionnaire for evaluation of quality of life (QOL) in adult patients with hypopituitarism.
Hitoshi Ishii +10 more
doaj +1 more source
Growth hormone deficiency during young adulthood and the benefits of growth hormone replacement [PDF]
Until quite recently, the management of children with growth hormone deficiency (GHD) had focussed on the use of recombinant human GH (rhGH) therapy to normalise final adult height.
Ahmed, S.F. +3 more
core +2 more sources
Non-functioning pituitary adenoma underwent surgery: a multicenter retrospective study over the last four decades (1977–2015) [PDF]
[Abstract] Objective. To assess clinical features, diagnostic procedures, therapies and outcomes in patients with clinically non-functioning pituitary adenomas (NFPAs) surgically treated over the last four decades. Design and methods.
Arcano, Karina +6 more
core +2 more sources
Genetic causes of hypopituitarism
Hypopituitarism in neonates is rare, but has life-threatening complications if untreated. This review describes the features of hypopituitarism and the evidence for which infants in whom a genetic cause should be suspected.
Katherine Parkin +3 more
doaj +1 more source
PurposeCongenital hypopituitarism usually occurs sporadically. In most patients, the etiology remains unknown.MethodsWe studied 13 children with sporadic congenital hypopituitarism. Children with non-endocrine, non-familial idiopathic short stature (NFSS)
Youn Hee Jee +14 more
doaj +1 more source
Sheehan's syndrome (postpartum hypopituitarism), report of a case [PDF]
A case of postpartum necrosis of the anterior lobe of the pituitary, known as Sheehan's syndrome, is presented. The patient has done well on a combined replacement therapy with cortisone and thyroid.
Kibata, Masayoshi, Miyoshi, Isao
core +1 more source
Homozygous CDH2 variant may be associated with hypopituitarism without neurological disorders
Context: Congenital hypopituitarism is a genetically heterogeneous cond ition. Whole exome sequencing (WES) is a promising approach for molecular di agnosis of patients with this condition.
Nathalia G B P Ferreira +19 more
doaj +1 more source
A review on the diagnosis and treatment of patients with clinically nonfunctioning pituitary adenoma by the Neuroendocrinology Department of the Brazilian Society of Endocrinology and Metabolism [PDF]
Clinically nonfunctioning pituitary adenomas (NFPA) are the most common pituitary tumors after prolactinomas. The absence of clinical symptoms of hormonal hypersecretion can contribute to the late diagnosis of the disease.
Araújo, Luiz Antônio de +9 more
core +3 more sources

