Growth hormone deficiency during young adulthood and the benefits of growth hormone replacement [PDF]
Until quite recently, the management of children with growth hormone deficiency (GHD) had focussed on the use of recombinant human GH (rhGH) therapy to normalise final adult height.
Ahmed, S.F.+3 more
core +2 more sources
Hypopituitarism in the tropics
Pituitary disorders, including hypopituitarism and hypothalamic pituitary insufficiency (HPI), are common conditions seen by endocrinologists in tertiary/referral centers. The important causes of hypopituitarism are pituitary tumors (including craniopharyngioma), postoperative and postradiotherapy states, vascular conditions, autoimmune diseases such ...
Vaman Khadilkar+2 more
openaire +4 more sources
Hypopituitarism: A Sequela of Severe Hypoxic Encephalopathy
Central diabetes insipidus (DI) is an established phenomenon after hypoxic encephalopathy or brain death, but hypopituitarism is seldom described. This study investigated the characteristics of 11 patients with DI and hypopituitarism which developed ...
Deng-Huang Su
doaj +1 more source
PurposeCongenital hypopituitarism usually occurs sporadically. In most patients, the etiology remains unknown.MethodsWe studied 13 children with sporadic congenital hypopituitarism. Children with non-endocrine, non-familial idiopathic short stature (NFSS)
Youn Hee Jee+14 more
doaj +1 more source
Non-functioning pituitary adenoma underwent surgery: a multicenter retrospective study over the last four decades (1977–2015) [PDF]
[Abstract] Objective. To assess clinical features, diagnostic procedures, therapies and outcomes in patients with clinically non-functioning pituitary adenomas (NFPAs) surgically treated over the last four decades. Design and methods.
Arcano, Karina+6 more
core +2 more sources
Background Metastasis to the pituitary gland is an infrequent clinical problem, and the symptoms caused by metastases have been reported in only 2.5–18.2% of the cases.
Ryohei Ono+5 more
doaj +1 more source
Effects of human recombinant growth hormone on exercise capacity, cardiac structure, and cardiac function in patients with adult-onset growth hormone deficiency [PDF]
Objective Epidemiological studies suggest that adult-onset growth hormone deficiency (AGHD) might increase the risk of death from cardiovascular causes. Methods This was a 6-month double-blind, placebo-controlled, randomised, cross-over trial followed by
Atkin, S. L.+11 more
core +1 more source
Development and validation of a new questionnaire assessing quality of life in adults with hypopituitarism: Adult Hypopituitarism Questionnaire (AHQ). [PDF]
OBJECTIVE: To develop and validate the Adult Hypopituitarism Questionnaire (AHQ) as a disease-specific, self-administered questionnaire for evaluation of quality of life (QOL) in adult patients with hypopituitarism.
Hitoshi Ishii+10 more
doaj +1 more source
Sheehan's syndrome (postpartum hypopituitarism), report of a case [PDF]
A case of postpartum necrosis of the anterior lobe of the pituitary, known as Sheehan's syndrome, is presented. The patient has done well on a combined replacement therapy with cortisone and thyroid.
Kibata, Masayoshi, Miyoshi, Isao
core +1 more source
Homozygous CDH2 variant may be associated with hypopituitarism without neurological disorders
Context: Congenital hypopituitarism is a genetically heterogeneous cond ition. Whole exome sequencing (WES) is a promising approach for molecular di agnosis of patients with this condition.
Nathalia G B P Ferreira+19 more
doaj +1 more source