Hypopituitarism: A Sequela of Severe Hypoxic Encephalopathy
Central diabetes insipidus (DI) is an established phenomenon after hypoxic encephalopathy or brain death, but hypopituitarism is seldom described. This study investigated the characteristics of 11 patients with DI and hypopituitarism which developed ...
Deng-Huang Su
doaj +1 more source
Introduction Individuals with traumatic brain injury (TBI) or subarachnoid hemorrhage (SAH) are at a high risk of hypopituitarism, and should benefit from early diagnosis and management.
Shigeyuki Tahara +2 more
doaj +1 more source
Background Metastasis to the pituitary gland is an infrequent clinical problem, and the symptoms caused by metastases have been reported in only 2.5–18.2% of the cases.
Ryohei Ono +5 more
doaj +1 more source
Development and validation of a new questionnaire assessing quality of life in adults with hypopituitarism: Adult Hypopituitarism Questionnaire (AHQ). [PDF]
OBJECTIVE: To develop and validate the Adult Hypopituitarism Questionnaire (AHQ) as a disease-specific, self-administered questionnaire for evaluation of quality of life (QOL) in adult patients with hypopituitarism.
Hitoshi Ishii +10 more
doaj +1 more source
Growth hormone deficiency during young adulthood and the benefits of growth hormone replacement [PDF]
Until quite recently, the management of children with growth hormone deficiency (GHD) had focussed on the use of recombinant human GH (rhGH) therapy to normalise final adult height.
Ahmed, S.F. +3 more
core +2 more sources
The presence of subclinical or minor pituitary hormone deficiencies could be recognised in clinical practice and might represent intermediate situations among normal pituitary hormone secretion and clinical hypopituitarism. However, this entity has not been correctly identified and associated clinical impairment and even more, long-term consequences ...
Fernández Rodríguez, Eva +3 more
openaire +3 more sources
Effects of human recombinant growth hormone on exercise capacity, cardiac structure, and cardiac function in patients with adult-onset growth hormone deficiency [PDF]
Objective Epidemiological studies suggest that adult-onset growth hormone deficiency (AGHD) might increase the risk of death from cardiovascular causes. Methods This was a 6-month double-blind, placebo-controlled, randomised, cross-over trial followed by
Atkin, S. L. +11 more
core +1 more source
Glycometabolic Alterations in Secondary Adrenal Insufficiency: Does Replacement Therapy Play a Role? [PDF]
Secondary adrenal insufficiency (SAI) is a potentially life-threatening endocrine disorder due to an impairment of corticotropin (ACTH) secretion from any process affecting the hypothalamus or pituitary gland.
Gianfrilli, Daniele +5 more
core +2 more sources
Homozygous CDH2 variant may be associated with hypopituitarism without neurological disorders
Context: Congenital hypopituitarism is a genetically heterogeneous cond ition. Whole exome sequencing (WES) is a promising approach for molecular di agnosis of patients with this condition.
Nathalia G B P Ferreira +19 more
doaj +1 more source
Non-functioning pituitary adenoma underwent surgery: a multicenter retrospective study over the last four decades (1977–2015) [PDF]
[Abstract] Objective. To assess clinical features, diagnostic procedures, therapies and outcomes in patients with clinically non-functioning pituitary adenomas (NFPAs) surgically treated over the last four decades. Design and methods.
Arcano, Karina +6 more
core +2 more sources

