Results 71 to 80 of about 34,733 (291)
Congenital Hypopituitarism: Various Genes, Various Phenotypes
Hormone and Metabolic Research, 2019 The ontogenesis and development of the pituitary gland is a highly complex process that depends on a cascade of transcription factors and signaling molecules.
M. Xatzipsalti +4 more
semanticscholar +1 more source
Frontiers in Endocrinology, 2023 ObjectiveTo describe the frequency of hypophysitis and hypopituitarism in cancer patients who are undergoing antineoplastic treatment with immunotherapy, as well as to describe the clinical, epidemiological, and demographic characteristics of these ...
Juliana Prudêncio Jacques +4 more
doaj +1 more source
Regulation of PHOX2B gene expression by the long non‐coding natural antisense RNA PHOX2B‐AS1
The FEBS Journal, EarlyView.PHOX2B is a transcription factor essential for autonomic nervous system development. We identify and characterize PHOX2B‐AS1, a human long non‐coding antisense transcript at the PHOX2B locus, along with its murine counterpart. Our findings reveal bidirectional transcription and reciprocal regulation: PHOX2B activates PHOX2B‐AS1, whereas PHOX2B‐AS1 ...
Simona Di Lascio +12 more
wiley +1 more source
Acromegaly: pathogenesis & treatment [PDF]
, 2019 Acromegaly is a multi-system disorder whose etiology is most often traced back to a growth hormone-secreting pituitary adenoma (PA). Growth hormone (GH) secretion promotes insulin-like growth factor 1 (IGF-1) release from peripheral tissues, leading to ...
Tilvawala, Megha
core
Thyroxine-binding globulin: investigation of microheterogeneity [PDF]
, 1981 Preparations of T4-binding globulin (TBG) from human serum was performed using only two affinity chromatography steps. Purity of the protein was demonstrated by a single band in overloaded disc and sodium dodecyl sulfate electrophoresis, equimolar ...
Gärtner, Roland +4 more
core +1 more source
Haemophilia, EarlyView.ABSTRACT Introduction The bispecific monoclonal antibody emicizumab was approved for prophylactic treatment of congenital haemophilia A (HA) in Japan in 2018. Aim To monitor long‐term safety and effectiveness of emicizumab, including appropriate concomitant use of bypassing agents (BPAs), in Japanese patients with congenital HA with inhibitors who ...
Midori Shima +7 more
wiley +1 more source
Traumatic brain injury and hypopituitarism
Advances in Clinical Neuroscience & Rehabilitation, 2019 Evidence demonstrates that the prevalence of hypopituitarism after traumatic brain injury (TBI) is higher than previously anticipated and leads to significant morbidity.
Sarah Leeder
doaj +1 more source
Mechanistic insight into the pathology of polyalanine expansion disorders revealed by a mouse model for x linked hypopituitarism [PDF]
, 2013 Extent: 9 p.Polyalanine expansions in transcription factors have been associated with eight distinct congenital human diseases. It is thought that in each case the polyalanine expansion causes misfolding of the protein that abrogates protein function ...
A Albrecht +29 more
core +3 more sources
Periodontal and orthodontic management of impacted canines
Periodontology 2000, EarlyView.Abstract The maxillary and mandibular canines are described by many clinicians as the “cornerstone” of the arch. When in their optimal position, they play a critical role in providing a well‐balanced occlusal scheme that contributes toward functional as well as neuromuscular stability, harmony, esthetics, and dentofacial balance.
Mohammad Qali +3 more
wiley +1 more source
Neuropsychiatric Disturbances and Hypopituitarism After Traumatic Brain Injury in an Elderly Man
Journal of the Formosan Medical Association, 2006 Neuropsychiatric or cognitive disturbances are common complications after traumatic brain injury. They are commonly regarded as irreversible sequelae of organic brain injuries.
Yi-Cheng Chang, Fen-Yu Tseng
doaj +1 more source