Results 81 to 90 of about 34,733 (291)
Case Report: Hypopituitarism Presenting With Nonconvulsive Status Epilepticus
Introduction: Hypopituitarism is defined as one or more partial or complete pituitary hormone deficiencies. Nonconvulsive status epilepticus (NCSE) refers to a state of continuous or repetitive seizures without convulsions.
Huimin Li +5 more
doaj +1 more source
ABSTRACT Objectives Metabolic dysfunction‐associated steatotic liver disease (MASLD) is a growing public health concern that contributes to liver and cardiovascular complications. The prevalence of MASLD in women increases sharply around age 50 years, but the relationship between an earlier age at natural menopause and MASLD is unknown.
Joshua Stokar, Rivka Dresner‐Pollak
wiley +1 more source
Type 1 Diabetes and Other Autoimmune Diseases—Epidemiology, Pathophysiology and Screening
Individuals with type 1 diabetes exhibit significantly increased prevalence of additional autoimmune diseases. Epidemiological, familial and mechanistic evidence indicates frequent polyautoimmunity and shared genetic and environmental drivers. Coexistence complicates clinical management, and autoantibody‐based detection often identifies preclinical ...
George J. Kahaly +6 more
wiley +1 more source
Hypoglycemia as a presenting manifestation of Sheehan’s syndrome
Sheehan’s syndrome is caused by ischemic necrosis of the pituitary gland from massive postpartum uterine bleeding. Despite advances in obstetric care, it is still an important cause of hypopituitarism in developing countries.
Mandeep Singla, Geetika Garg
doaj +1 more source
Glucocorticoid replacement therapy, available since the 1950s, has prolonged the survival of patients with adrenal insufficiency. However, adrenal crises, which are life-threatening medical emergencies, still develop in many affected patients.
Falhammar, Henrik +2 more
core +1 more source
The Pathogenic TSH β-Subunit Variant C105Vfs114X Causes a Modified Signaling Profile at TSHR [PDF]
1) Background: Central congenital hypothyroidism (CCH) is a rare endocrine disorder that can be caused by mutations in the β-subunit of thyrotropin (TSHB).
Biebermann, Heike +6 more
core +1 more source
Harbouring a silent corticotroph tumour (SCT) compared to a silent gonadotroph tumour, being older at surgery and having a larger preoperative tumour were found to increase the likelihood of having postoperative pituitary failure in logistic regression analysis (n = 77).
Nasrin Al‐Shamkhi +5 more
wiley +1 more source
Background Early diagnosis of lymphoma involving the central nervous system is sometimes difficult but emergent to avoid the delay of therapeutic initiation. Pituitary insufficiencies are usually associated with lymphoma in the pituitary gland.
Shohei Kishimoto +11 more
doaj +1 more source
ABSTRACT Objective and Background Early identification of adrenal insufficiency (AI) during immune‐checkpoint inhibitors (ICIs) is crucial to prevent life‐threatening consequences; however, the diagnosis is challenging. Design, Patients and Measurement In this prospective observational study, ICI‐treated cancer patients with morning serum cortisol (SC)
Alice Nervo +6 more
wiley +1 more source
A Case of Ipilimumab Induced Hypophysitis [PDF]
Introduction Ipilimumab (Yervoy®) is a human monoclonal antibody that has been shown to significantly improve survival in cases of metastatic melanoma.1 Ipilimumab blocks cytotoxic T-lymphocyte antigen 4 (CTLA-4), a protein receptor on the surface of T ...
Shiffrin, MD, Eric +1 more
core +2 more sources

