Results 231 to 240 of about 26,524 (303)
Abstract Aims Acquired hypothalamic obesity (aHO) following craniopharyngioma (CP) is a challenging condition with limited therapeutic options. This study aimed to assess the real‐world effectiveness and safety of GLP‐1 RAs in this population. Materials and Methods CranioGLP1 is a retrospective multicentre study including 116 adults with aHO treated ...
Flora Lambert +28 more
wiley +1 more source
The analysis indicates differential associations of body roundness index and body mass index with obstructive sleep apnea and subsequent mortality, subtly pointing to the importance of adiposity distribution in shaping clinical trajectories. ABSTRACT Background Being obese considerably elevates the risk of both obstructive sleep apnea syndrome (OSAS ...
Xiaodong Chen +3 more
wiley +1 more source
A precision trial case study for heterogeneous treatment effects in obstructive sleep apnea
Abstract Precision medicine tailors treatments to individual patient characteristics, which is especially valuable for obstructive sleep apnea (OSA), where treatment responses vary widely. Traditional trials often overlook subgroup differences, leading to suboptimal recommendations.
Lara Maleyeff +3 more
wiley +1 more source
The CYP3A5 rs776746 CC genotype is a strong biomarker for ticagrelor‐induced dyspnea, conferring a 2.3‐fold higher risk. Genotype‐guided antiplatelet therapy may mitigate this adverse reaction, enabling personalized treatment for ACS patients. ABSTRACT Background Dual antiplatelet therapy with aspirin and a P2Y₁₂ inhibitor is standard for patients with
Yanming Zhang +5 more
wiley +1 more source
Body Mass Index and Hypoglossal Nerve Stimulation Outcomes: A Systematic Review and Meta‐Analysis
This systematic review and meta‐analysis evaluated the impact of elevated body mass index (BMI) on outcomes following hypoglossal nerve stimulation (HGNS) for obstructive sleep apnea. Across seven studies, higher BMI, particularly, above the 32 kg/m2 cutoff‐was associated with reduced treatment response rates, though many patients still achieved ...
Coleton Evans +4 more
wiley +1 more source
Parent Reports Versus Objective Behavioral Measures in Pediatric Sleep‐Disordered Breathing
Among children with SDB, we observed limited agreement between parent‐reported behavioral problems and objective assessments of response inhibition. Although parent‐reported inhibitory issues initially showed a weak, statistically significant correlation with performance‐based attention measures in unadjusted analyses, this relationship was mitigated ...
Daniel C. Fong +5 more
wiley +1 more source
Research Progress on External Treatment Methods of Traditional Chinese Medicine for Obstructive Sleep Apnea-Hypopnea Syndrome [PDF]
鹏飞 马
openalex +1 more source
Quality of Life in Chronic Heart Failure With Obstructive Sleep Apnea: A Systematic Review
ABSTRACT Aim To describe the quality of life in patients with chronic heart failure and coexisting obstructive sleep apnoea, and to examine the effect of common sleep‐disordered breathing treatments on quality of life, functional capacity and cardiac outcomes. Design Systematic review.
Francesco Limonti +7 more
wiley +1 more source

