Results 41 to 50 of about 2,926 (153)
Periodontal Disease and Salivary Gland Dysfunction in Neurofibromatosis Type 1: A Case–Control Study
Oral Diseases, EarlyView.ABSTRACT Objectives Neurofibromatosis type 1 (NF1) presents with diverse systemic and oral manifestations. The aim of this study was to investigate the periodontal status and salivary alterations in NF1 individuals. Methods A total of 38 individuals with NF1 diagnostic criteria were compared with a control group paired by age and sex.
Eloá Borges Luna +6 more
wiley +1 more source
Oral Diseases, EarlyView.ABSTRACT Objective To synthesize evidence on spirituality in patients with head and neck cancer (HNC), focusing on its dimensions, assessment strategies, and impact on health outcomes. Methods A comprehensive search of PubMed, Embase, LILACS, Web of Science, Scopus, and gray literature identified qualitative and quantitative studies explicitly ...
Liliana Wolf Braun +8 more
wiley +1 more source
Oral Health Screening Prior to Oncological Treatment—The Helsinki Protocol
Oral Diseases, EarlyView.ABSTRACT Objectives Oncological treatments can have adverse effects on oral health and cause long‐term complications such as osteonecrosis. This retrospective study investigated the oral health of head and neck cancer patients before radiotherapy and patients with multiple myeloma, breast, prostate, lung, and kidney cancers before antiresorptive ...
Jemina Järvinen +4 more
wiley +1 more source
Drug‐Induced Sialolithiasis—A Big‐Data Retrospective Study
Oral Diseases, EarlyView.ABSTRACT Background Sialolithiasis pathophysiology is multifactorial, with systemic medications often hypothesised as a key contributor, particularly in older adults (Drug‐Induced Sialolithiasis). However, robust evidence supporting this theory is limited.
Gal Avishai +5 more
wiley +1 more source
Antipsychotics‐Induced Hyposalivation Mediated by Impaired Salivary Ca2+ Signaling
Oral Diseases, EarlyView.ABSTRACT Objectives Antipsychotic‐induced salivary dysfunction such as hyposalivation is a prevalent clinical challenge that severely compromises oral health and quality of life. Although typical and atypical antipsychotics have their therapeutic target in the central nervous system, their direct molecular mechanisms within the salivary glands remain ...
Chaelin Chung +4 more
wiley +1 more source
Ion Channel Dysfunction and Therapeutic Targeting in Salivary Gland Disorders
Oral Diseases, EarlyView.ABSTRACT Objective Salivary gland hypofunction and xerostomia represent major clinical complications of radiation therapy, autoimmune disorders such as Sjögren's disease, and inherited epithelial ion transport defects. This review integrates current knowledge on ion channel dysfunction as a central mechanistic driver of salivary gland pathology and ...
Tarek Mohamed Abd El‐Aziz +6 more
wiley +1 more source
Restoring Mouth Opening in Systemic Sclerosis: A Scoping Review of Interventions
Oral Diseases, EarlyView.ABSTRACT Objectives To map and characterize the therapeutic strategies described in the literature for the management of microstomia in patients with systemic sclerosis. Methods This scoping review was conducted in accordance with the PRISMA‐ScR guidelines. Searches were performed in Medline/PubMed, Embase, Scopus, Web of Science, Cochrane Library, and
Beatriz Borba Barros Bernardo +5 more
wiley +1 more source
Psychophysical Assessment of Gustatory Function in Burning Mouth Syndrome: A Systematic Review
Oral Diseases, EarlyView.ABSTRACT Objective To evaluate whether psychophysically assessed gustatory function differs between adults with burning mouth syndrome and age‐ and sex‐matched healthy controls, and to explore related sensory and physiological factors. Methods This systematic review followed the Preferred Reporting Items for Systematic Reviews and Meta‐Analyses ...
Abas Jafari +2 more
wiley +1 more source
Periodontology 2000, EarlyView.Abstract Background Population aging is reshaping prosthodontic care for both partially and completely edentulous individuals. In older adults, conditions such as frailty, comorbidities, polypharmacy, and cognitive decline can have a direct impact on the biological and biomechanical demands of implant therapy, thereby influencing the success of implant
Yu‐Ting Yeh +10 more
wiley +1 more source
Clinical and Experimental Dental Research, Volume 12, Issue 4, August 2026.ABSTRACT Aims To investigate longitudinal alterations in oral hygiene, gingival inflammation, and salivary secretion during a 60‐day head‐down tilt bed rest (HDTBR) protocol as a validated ground‐based analog of microgravity. Materials and Methods Twenty‐four healthy volunteers participated in a 60‐day, 6° HDTBR study conducted under strictly ...
Sonja Henny Maria Derman +6 more
wiley +1 more source