Results 101 to 110 of about 26,178 (244)

Testosterone Exposure During Fetal Masculinization Programming Window Determines the Kidney Size in Adult Mice

The FASEB Journal, Volume 40, Issue 7, 15 April 2026.
Kidney size is sex‐dimorphic and regulated by androgens in adult humans and mice. Male mice lacking the main testosterone‐producing enzyme HSD17B3 had reduced testosterone during a short fetal time window, leading to reduced size of kidneys in adults, which were not responsive to high adult testosterone.
Arttu Junnila, Kalle T. Rytkönen, Guillermo Martinez‐Nieto, Mats Perk, Otto Mäkelä, Hao Li, Jenni Airaksinen, Ida Hyötyläinen, Oliver Mehtovuori, Asta Laiho, Claes Ohlsson, Laura L. Elo, Satu Kuure, Matti Poutanen, Petra Sipilä   +14 more
wiley   +1 more source

Penile Curvature Incidence in Hypospadias: Can It Be Determined?

Advances in Urology, 2011
The aim was to retrospectively determine the real incidence of congenital penile curvature in various forms of hypospadias, in order to indicate intraoperative assessment and correction of curvature.
Borko Stojanovic, Marta Bizic, Marko Majstorovic, Vladimir Kojovic, Miroslav Djordjevic   +4 more
doaj   +1 more source

Severe 180° Penile Torsion With False Meatus and Intact Prepuce Resembling Normal Anatomy in a 1.5‐Year‐Old Afghan Child: A Rare Case With Literature Review

Clinical Case Reports, Volume 14, Issue 4, April 2026.
ABSTRACT Congenital penile torsion is a rare rotational anomaly of the penis, usually directed counterclockwise, and may occur in isolation or with other penile malformations. It is usually asymptomatic but may lead to cosmetic or functional concerns in severe cases.
Turyalai Hakimi, Mohammad Anwar Jawed
wiley   +1 more source

Comparative Study of Urethral Plate and Glans Characteristics in Experimentally Created Hypospadias and Clinical Cases Undergoing Snodgrass Repair

Journal of Indian Association of Pediatric Surgeons
Aim: The aim of this study was to study the urethral plate and glans configuration in experimentally created hypospadias in male human cadavers and its comparison with hypospadias patients planned for tubularized incised plate (TIP) urethroplasty ...
Manish Rajput, Archika Gupta, Gurmeet Singh, Rahul Kumar Rai, Shiv Narain Kureel, Punita Manik, Navneet Chauhan, Jiledar Rawat   +7 more
doaj   +1 more source

Electro‐clinical features of Mowat–Wilson syndrome: A retrospective study of 31 children in mainland China

Epileptic Disorders, Volume 28, Issue 2, Page 344-358, April 2026.
Abstract Objective To summarize the electro‐clinical and genetic characteristics of children with Mowat–Wilson syndrome (MWS). Methods This study is a hospital‐based case series analyzing clinical data from 31 pediatric patients with MWS and epilepsy treated at Peking University First Hospital between June 2020 and December 2024.
Yi Ju, Tao‐yun Ji
wiley   +1 more source

Novel Variants in KMT2C Further Support a Neurodevelopmental Disorder Distinct From Kleefstra and Kabuki Syndromes

Molecular Genetics &Genomic Medicine, Volume 14, Issue 4, April 2026.
Sedlackova et al. describe detailed phenotypes of three patients with novel variants in the KMT2C gene. After detailed phenotypic analysis, we found that our patients have phenotypes very similar to those previously described as KMT2C‐related Kleefstra syndrome 2, and thus further extend the list of KMT2C causal variants.
Lucie Sedláčková, Dana Šafka Brožková, Markéta Havlovicová, Petra Laššuthová   +3 more
wiley   +1 more source

Low Risk for Urinary Tract Infection After Voiding Cystography in Children Without Dilated Vesikoureteral Reflux

Acta Paediatrica, Volume 115, Issue 4, Page 972-977, April 2026.
ABSTRACT Aim Urinary tract infection (UTI) is the most common and significant complication after voiding cystourethrography (VCUG) but the reported incidence in children varies highly. Therefore, the aim of this study was to evaluate the rate and possible risk factors for UTIs after VCUG. Method A multicentre retrospective cohort study of children < 15 
Emelie Widhe, Mette Hambraeus, Erik Hedström, Anna Börjesson, Martin Salö   +4 more
wiley   +1 more source

Complaints of Men with Uncorrected Distal Hypospadias

Research and Reports in Urology, 2023
Nicol Corbin Bush, Warren Snodgrass The Hypospadias Specialty Center, The Colony, TX, USACorrespondence: Nicol Corbin Bush, Email bush@hypospadias.comPurpose: The few available reports regarding adults living with distal hypospadias give disparate views ...
Bush NC, Snodgrass W
doaj  

Detection of the Heterozygous Recurrent MAX p.(Arg60Gln) Variant in Two Females Confirms and Expands the Phenotypic Spectrum of Polydactyly–Macrocephaly Syndrome

Clinical Genetics, Volume 109, Issue 4, Page 788-795, April 2026.
We identified a recurrent heterozygous MAX c.179G>A:p.Arg60Gln variant in two unrelated females affected with the emerging phenotypes of MAX‐associated polydactyly‐macrocephaly syndrome. We propose that genitourinary abnormalities, including Mayer–Rokitanski–Kuster–Hauser syndrome in one individual, are an expansion of the known phenotypes associated ...
Iftekhar A. Showpnil, Neta Feinstein‐Goren, Lior Greenbaum, Ortal Barel, Daniel C. Koboldt, Samantha A. Brugmann, Kathryn Nicole Weaver, Anne Slavotinek, Ben Pode‐Shakked, Rolf W. Stottmann   +9 more
wiley   +1 more source

Prevalence and Factors Associated with Urologic Abnormalities in Hypospadias Patients

Siriraj Medical Journal
Objective: To estimate the prevalence of urinary tract abnormalities in boys with hypospadias and identify clinical factors that warrant screening. Materials and Methods: A retrospective review was conducted of patients with hypospadias treated at ...
Donlaporn Rungwilaicharoen, Ravit Ruangtrakool   +1 more
doaj