Results 91 to 100 of about 136,879 (260)

Synergistic Pressor Effect of Atomoxetine and Pyridostigmine in Patients With Neurogenic Orthostatic Hypotension

HYPERTENSION, 2019
Patients with autonomic failure are characterized by disabling orthostatic hypotension because of impaired sympathetic activity, but even severely affected patients have residual sympathetic tone which can be harnessed for their treatment.
L. Okamoto, C. Shibao, A. Gamboa, A. Diedrich, S. Raj, Bonnie K. Black, D. Robertson, I. Biaggioni   +7 more
semanticscholar   +1 more source

Human hypoxia models in aerospace medicine: Potential applications for human pharmacological research

British Journal of Clinical Pharmacology, EarlyView.
Aerospace medicine required controlled terrestrial models to investigate influences of altered atmosphere conditions, such as hypoxia, on human health and performance. These models could potentially be expanded to encompass disease conditions or treatment targets regulated through hypoxia or hypercapnia.
Titiaan E. Post, Cayla Denney, Adam Cohen, Jens Jordan, Ulrich Limper   +4 more
wiley   +1 more source

Orthostatic hypotension secondary to a suspected thymoma in a dog: a case report

BMC Veterinary Research, 2020
Background This is the first case report description, to our knowledge, of a cranial mediastinal mass (suspected thymoma) causing orthostatic hypotension in a dog.
Jeremy Hansford, Natalia Henao-Guerrero
doaj   +1 more source

Real‐life experience of luspatercept in transfusion‐dependent lower risk myelodysplastic syndrome patients

British Journal of Haematology, EarlyView.
This retrospective multicentre study included 98 TD LR‐MDS patients who had failed prior erythropoietin treatment and were subsequently treated with luspatercept. Red blood cell (RBC) transfusion requirements were recorded in the last 16 weeks before luspatercept initiation and response rates consecutively declined in patient groups receiving 1–2 ...
Anthi Bouchla, Sotirios G. Papageorgiou, Ioannis Kotsianidis, Panagiotis Diamantopoulos, Eleni Gavriilaki, Eleni Bouronikou, Argiris Symeonidis, Panagiotis Zikos, Mustafa Cetiner, Efthymia Vlachaki, Akrivi Kostourou, Athanasios Galanopoulos, Eleftheria Hatzimichael, Elisavet‐Christina Vervesou, Sinem Civriz Bozdağ, Nora‐Athina Viniou, Dimitrios Christoulas, Maria Dellatola, Maria Papaioannou, Menelaos Papoutselis, Dimitra Vlachopoulou, Antonia Syrigou, Maria Mainou, Sofia Chatzileontiadou, Vasiliki Pappa   +24 more
wiley   +1 more source

Clinical Assessment of Fluid Status in Adults With Acute Kidney Injury: A Scoping Review. [PDF]

J Ren Care
ABSTRACT Background Acute kidney injury refers to sudden, potentially reversible, reduction in kidney function. Hypovolaemia is commonly the major risk factor. When acute kidney injury is established, fluid can accumulate leading to fluid overload. Undertaking a rigorous fluid assessment is vital in the management of a patient in hospital with acute ...
Nagalingam K, Whiting L, Farrington K, Migliozzi J, Pattison N.   +4 more
europepmc   +2 more sources

Late‐onset multiple system atrophy: Neuropathological features associated with slow disease progression

Brain Pathology, EarlyView.
Late‐onset multiple system atrophy (LO‐MSA; onset ≥75 years) shows milder degeneration of the striatonigral and olivopontocerebellar systems and serotonergic neurons in the ventrolateral medulla than usual‐age‐onset MSA with a similar disease duration. LO‐MSA may therefore exhibit slower pathological progression.
Misato Ozawa, Rie Saito, Takuya Konno, Yasuko Kuroha, Tetsuhiko Ikeda, Akio Yokoseki, Takashi Tani, Tomoe Sato, Jiro Idezuka, Reiji Koide, Shigeru Fujimoto, Osamu Onodera, Mari Tada, Akiyoshi Kakita   +13 more
wiley   +1 more source

Diagnosis and treatment of orthostatic hypotension

Lancet Neurology, 2022
W. Wieling, H. Kaufmann, V. Claydon, V. K. Wijnen, M. Harms, Stephen P. Juraschek, R. Thijs   +6 more
semanticscholar   +1 more source

Association of orthostatic hypotension with incident dementia, stroke, and cognitive decline

Neurology, 2018
Objective To examine associations of orthostatic hypotension (OH) with dementia and long-term cognitive decline and to update previously published results in the same cohort for stroke with an additional 16 years of follow-up.
Andreea M. Rawlings, Andreea M. Rawlings, Stephen P. Juraschek, Stephen P. Juraschek, G. Heiss, T. Hughes, M. Meyer, E. Selvin, A. Sharrett, B. Windham, R. Gottesman   +10 more
semanticscholar   +1 more source

Self‐reported autonomic dysfunction could be a predictive marker for sarcopenia in Parkinson's disease

Geriatrics &Gerontology International, EarlyView.
Autonomic dysfunction, assessed by the Scales for Outcomes in Parkinson's Disease‐Autonomic Questionnaire, was significantly associated with sarcopenia in patients with Parkinson's disease. Among all autonomic domains, the gastrointestinal score had the strongest predictive ability for sarcopenia.
Motohiro Okumura, Yohei Mukai, Reiko Saika, Yuji Takahashi   +3 more
wiley   +1 more source

The recommendations of a consensus panel for the screening, diagnosis, and treatment of neurogenic orthostatic hypotension and associated supine hypertension

Journal of Neurology, 2017
Neurogenic orthostatic hypotension (nOH) is common in patients with neurodegenerative disorders such as Parkinson’s disease, multiple system atrophy, pure autonomic failure, dementia with Lewy bodies, and peripheral neuropathies including amyloid or ...
C. Gibbons, P. Schmidt, I. Biaggioni, Camille G. Frazier-Mills, R. Freeman, S. Isaacson, B. Karabin, L. Kuritzky, M. Lew, P. Low, A. Mehdirad, S. Raj, S. Vernino, H. Kaufmann   +13 more
semanticscholar   +1 more source