Results 101 to 110 of about 135,663 (215)

Self‐Reported Motor and Nonmotor Symptoms, Prodromal Parkinson's Disease Probability, and Incident Parkinson's Disease in US Farmers

open access: yesMovement Disorders, EarlyView.
Abstract Background Few studies have assessed motor and nonmotor symptoms and the prodromal probability of Parkinson's disease (PD) among farming populations. Objective The aim was to assess self‐reported nonmotor and motor symptoms and the prodromal PD probability in relation to incident PD among US farmers.
Shengfang Song   +10 more
wiley   +1 more source

The Proportion of Orthostatic Hypotension and Its Relationship with HbA1c Levels in Elderly Patients with Diabetes

open access: yesActa Medica Indonesiana, 2016
Aim: to obtain information on the proportion of orthostatic hypotension in elderly patients with diabetes and its relationship with HbA1c levels. Methods: this is a cross-sectional study on 350 patients with diabetes mellitus (DM) aged ≥60 years old who ...
Catarina Budyono   +3 more
doaj  

Multivariate Time-series Similarity Assessment via Unsupervised Representation Learning and Stratified Locality Sensitive Hashing: Application to Early Acute Hypotensive Episode Detection [PDF]

open access: yesarXiv, 2018
Timely prediction of clinically critical events in Intensive Care Unit (ICU) is important for improving care and survival rate. Most of the existing approaches are based on the application of various classification methods on explicitly extracted statistical features from vital signals. In this work, we propose to eliminate the high cost of engineering
arxiv  

Orthostatic hypotension as a risk factor for longitudinal deterioration of cognitive function in the elderly

open access: yesEuropean Journal of Neurology, 2019
Orthostatic hypotension is frequent with aging with a prevalence of 20%–30% in people aged 65 or older and is considered to increase the risk for coronary events, strokes and dementia.
M. Zimmermann   +11 more
semanticscholar   +1 more source

NLX‐112 Randomized Phase 2A Trial: Safety, Tolerability, Anti‐Dyskinetic, and Anti‐Parkinsonian Efficacy

open access: yesMovement Disorders, EarlyView.
Abstract Background Levodopa‐induced dyskinesia (LID) in Parkinson's disease (PD) is associated with ‘false neurotransmitter’ release of dopamine from serotonin (5‐HT) neurons. NLX‐112 is a first‐in‐class, highly selective 5‐HT1A receptor agonist which counteracts LIDs in experimental PD models.
Per Svenningsson   +13 more
wiley   +1 more source

Neurogenic Orthostatic Hypotension in Parkinson Disease: A Primer

open access: yesNeurological Therapeutics, 2019
Parkinson disease (PD) is associated with a variety of motor and non-motor clinical manifestations, including cardiovascular autonomic dysfunction.
J. Cutsforth-Gregory, P. Low
semanticscholar   +1 more source

Transcutaneous Tibial Nerve Stimulation for Overactive Bladder Symptoms in Parkinson's Disease: Results from a Phase II Randomized Control Trial (STRIPE)

open access: yesMovement Disorders, EarlyView.
Abstract Background Lower urinary tract symptoms (LUTS) are common Parkinson's disease (PD), causing great impact. Objective The goal was to undertake a phase II randomized control trial of transcutaneous tibial nerve stimulation (TTNS) delivered by Geko device for LUTS related to overactive bladder (OAB) in PD, an easy to use of the shelf solution ...
Matthew D. Smith   +6 more
wiley   +1 more source

Treatment Selection and Prioritization for the EJS ACT‐PD MAMS Trial Platform

open access: yesMovement Disorders, EarlyView.
Abstract Background There are currently no disease‐modifying therapies (DMTs) registered for Parkinson's disease (PD). The Edmond J. Safra Accelerating Clinical Trials in Parkinson Disease (EJS ACT‐PD) initiative will expedite clinical assessment of putative DMTs through a multi‐arm multistage (MAMS) trial, testing several treatments against a common ...
Cristina Gonzalez‐Robles   +29 more
wiley   +1 more source

An Unusual Case of Neurogenic Orthostatic Hypotension Without Parkinsonian Features

open access: yesAnnals of Internal Medicine: Clinical Cases
Orthostatic hypotension is a common cause of syncope, especially in the older adult population. While it is a commonly encountered issue as a cause of syncope, neurogenic orthostatic hypotension (nOH) is less common.
Betul Gok Yavuz, Darian Fard, Asma Malik
doaj   +1 more source

Partial central diabetes insipidus after simultaneous pancreas-kidney transplantation exacerbated orthostatic hypotension in type 1 diabetes mellitus

open access: yesFujita Medical Journal, 2017
A 34-year-old woman with type 1 diabetes on hemodialysis was admitted to our hospital for simultaneous pancreas kidney transplantation received from her father.
Megumi Shibata   +7 more
doaj   +1 more source

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