Results 101 to 110 of about 136,879 (260)

Pharmacokinetics and safety of eptinezumab in children and adolescents with migraine

Headache: The Journal of Head and Face Pain, EarlyView.
Abstract Objective The primary objective was to characterize the pharmacokinetics (PK) and safety of eptinezumab in children and adolescents with migraine. Background Migraine in children and adolescents is a prevalent and potentially debilitating disease, and few preventive therapies are approved for use in these populations. Eptinezumab, a calcitonin
Andrew D. Hershey, Johan Areberg, Line Pickering Boserup, Annika Lindsten, Monika Rosen   +4 more
wiley   +1 more source

Atherosclerosis of the carotid bulb is associated with the severity of orthostatic hypotension in non-diabetic adult patients: a cross-sectional study

Clinical and Experimental Hypertension, 2019
Background: The carotid bulb has a high density of baroreceptors that play an important role in maintaining blood pressure. We hypothesized that atherosclerosis of the carotid bulb would reflect the severity of orthostatic hypotension more accurately ...
Yusuke Kobayashi, Hiroaki Ishiguro, Tetsuya Fujikawa, Hideo Kobayashi, Koichiro Sumida, Minako Kagimoto, Yuki Okuyama, Yosuke Ehara, Mari Katsumata, Megumi Fujita, Akira Fujiwara, Sanae Saka, Keisuke Yatsu, Nobuhito Hirawa, Yoshiyuki Toya, Gen Yasuda, Satoshi Umemura, Kouichi Tamura   +17 more
doaj   +1 more source

Orthostatic Hypotension and Risk of Clinical and Subclinical Cardiovascular Disease in Middle‐Aged Adults

Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease, 2018
Background Although orthostatic hypotension (OH) is a well‐recognized manifestation of neuropathy and hypovolemia, its contribution to cardiovascular disease (CVD) risk is controversial.
S. Juraschek, N. Daya, L. Appel, E. Miller, J. McEvoy, K. Matsushita, C. Ballantyne, E. Selvin   +7 more
semanticscholar   +1 more source

Syncope: Advances in Diagnosis and Treatment 2024

Journal of Cardiovascular Electrophysiology, EarlyView.
Vasovagal syncope advances in therapy. ABSTRACT Aim In light of many recent advances in the field of vasovagal syncope, a selective review has been undertaken of these developments. Methods Recent publications on the following topics were reviewed; understanding of vasovagal syncope pathophysiology, tilt‐testing methodology and interpretation, drug ...
Richard Sutton, Rose Anne Kenny, David G. Benditt   +2 more
wiley   +1 more source

Disappearance of orthostatic hypotension after pacemaker implantation in a patient with a long PR interval

Indian Heart Journal, 2013
Orthostatic hypotension is the fall in blood pressure when upright and has a high prevalence in elderly population. Diagnostic and therapeutic work-up can be long and difficult.
Elia De Maria, Pier Luigi Fontana, Stefano Cappelli   +2 more
doaj   +1 more source

Orthostatic hypotension and cardiovascular risk

Kardiologia Polska, 2019
Orthostatic hypotension (OH) is a cardinal sign of cardiovascular (CV) autonomic dysfunction as a result of autonomic nervous system failure to control the postural hemodynamic homeostasis. The proportion of individuals with OH increases with aging and chronic conditions, such as neurodegenerative diseases, hypertension, heart failure, diabetes, renal ...
Fabrizio Ricci, Artur Fedorowski, Artur Fedorowski, Richard Sutton, Richard Sutton   +4 more
openaire   +6 more sources

Orthostatic hypotension and symptomatic subclinical orthostatic hypotension increase risk of cognitive impairment: an integrated evidence review and analysis of a large older adult hypertensive cohort

European Heart Journal, 2018
Aims Systematically reviewing the literature found orthostatic hypotension (OH) to be associated with an increased risk of incident dementia but limited data were available in those at highest risk, the hypertensive oldest-old. Our aim was to analyse the
R. Peters, K. Anstey, A. Booth, N. Beckett, J. Warwick, R. Antikainen, K. Rockwood, J. Peters, C. Bulpitt   +8 more
semanticscholar   +1 more source

Impact of Discontinuation of Fall‐Risk‐Increasing Drugs on Falls in Multimorbid Older Patients With Polypharmacy

Journal of the American Geriatrics Society, EarlyView.
ABSTRACT Background Falls are a major concern in the older population. An important cause of falls is fall‐risk‐increasing drugs (FRID). However, it is not known if the discontinuation of FRID leads to a reduction of falls. Therefore, the aim of this study was to assess the association between discontinuation of FRID and the occurrence of falls and ...
Namiko A. Goto, Dayna A. M. van Heel, Lauren Dautzenberg, François‐Xavier Sibille, Emma Jennings, Douglas C. Bauer, Carole E. Aubert, Anne Spinewine, Nicolas Rodondi, Huiberdina L. Koek, Mariëlle H. Emmelot‐Vonk, Wilma Knol   +11 more
wiley   +1 more source

Diabetic gastroenteropathy: Associations between gastrointestinal symptoms, motility, and extraintestinal autonomic measures

Neurogastroenterology &Motility, EarlyView.
We found no associations between gastrointestinal and extraintestinal measures of diabetic autonomic neuropathy. Nonetheless, gastrointestinal symptoms increased with the severity of cardiovascular autonomic neuropathy and were associated with gastrointestinal measures.
Ditte S. Kornum, Christina Brock, Tina Okdahl, Davide Bertoli, Huda Kufaishi, Anne‐Marie Wegeberg, Katrine L. Høyer, Esben B. Mark, Birgitte Brock, Christian S. Hansen, Filip K. Knop, Asbjørn M. Drewes, Klaus Krogh   +12 more
wiley   +1 more source

The efficacy of nonpharmacologic intervention for orthostatic hypotension associated with aging

Neurology, 2018
Objective To determine the efficacy and safety of nonpharmacologic interventions for orthostatic hypotension (OH) secondary to aging. Methods A total of 150 orthostatic challenges were performed in 25 older people (age 60–92 years) to determine ...
J. Newton, J. Frith
semanticscholar   +1 more source