Results 111 to 120 of about 136,879 (260)
Women in space: A review of known physiological adaptations and health perspectives
Experimental Physiology, EarlyView.Abstract Exposure to the spaceflight environment causes adaptations in most human physiological systems, many of which are thought to affect women differently from men. Since only 11.5% of astronauts worldwide have been female, these issues are largely understudied.
Millie Hughes‐Fulford +4 more
wiley +1 more source
Treatment of Orthostatic Hypotension with Erythropoietin
New England Journal of Medicine, 1993 Patients with orthostatic hypotension caused by autonomic neuropathy frequently have a decreased red-cell mass. This would be expected to compromise their effective circulating blood volume and aggravate the orthostatic hypotension. We studied the effect of increasing the red-cell mass with erythropoietin, given subcutaneously in a dose of 50 U per ...
Hoeldtke, Robert D. +1 more
openaire +4 more sources
Orthostatic Hypotension in the Hypertensive Patient.
American Journal of Hypertension, 2018 Orthostatic hypotension (OH) is an important and common medical problem, particularly in the frail elderly with multiple comorbidities and polypharmacy. OH is an independent risk factor for falls and overall mortality.
I. Biaggioni
semanticscholar +1 more source
Experimental Physiology, EarlyView.Abstract Blood flow restriction (BFR) has been identified as a potential countermeasure to mitigate physiological deconditioning during spaceflight. Guidelines recommend that tourniquet pressure be prescribed relative to limb occlusion pressure (LOP); however, it is unclear whether body tilting or reduced gravity analogues influence LOP.
Patrick Swain, Nick Caplan, Luke Hughes
wiley +1 more source
Skin Nerve Phosphorylated &agr;-Synuclein Deposits in Parkinson Disease With Orthostatic Hypotension
Journal of Neuropathology and Experimental Neurology, 2018 This study aimed to investigate phosphorylated α-synuclein (p-syn) in autonomic skin nerves of Parkinson disease (PD) patients with and without orthostatic hypotension (OH).
V. Donadio +10 more
semanticscholar +1 more source
Experimental Physiology, EarlyView.Abstract This narrative review highlights the impact of exercise on vascular health in females over the lifespan with an emphasis on puberty, pregnancy and menopause. These events encompass substantial changes in sex hormone levels, particularly oestrogens and progesterone.
Kathleen B. Miller +2 more
wiley +1 more source
Experimental Physiology, EarlyView.Abstract Central artery stiffening increases the haemodynamic pulsations transmitted downstream towards target organs, including the brain. While recent evidence suggests that long duration spaceflight is associated with reduced common carotid artery (CCA) distensibility, cerebrovascular pulsatility has not been extensively characterized in astronauts.
Roxanne Fournier +5 more
wiley +1 more source
Spontaneous Intracranial Hypotension: Brain and Spinal MRI Findings
Ankara Üniversitesi Tıp Fakültesi Mecmuas, 2017 Aim: Spontaneous intracranial hypotension is a rare syndrome, characterized by orthostatic headache associated with a low cerebrospinal fluid pressure. The aim of this study is to examine the brain and spinal magnetic resonance imaging (MRI) findings of ...
Mehtap Çavușoğlu +5 more
doaj +1 more source
Plasticity of the heart in response to changes in physical activity
The Journal of Physiology, EarlyView.Abstract figure legend The heart adapts to changes in physical activity, with inactivity (e.g. bed rest or spaceflight) causing cardiac atrophy and ventricular stiffening, and endurance exercise training leading to eccentric hypertrophy and improved ventricular compliance.
Eric T. Hedge +3 more
wiley +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend Schematic illustration of the bidirectional causative link between cerebral amyloid‐beta (Aβ) angiopathy and cardiovascular disease in Alzheimer's disease (AD). Common cardiovascular risk factors like microvascular thrombosis, diabetes, atrial fibrillation, hypertension and atherosclerosis lead to cerebral hypoperfusion and ...
Samuel Parker +2 more
wiley +1 more source