Results 81 to 90 of about 159,287 (258)

Penyidikan Efek Samping Haloperidol Dan Chlorpromazine : Studi Kasus Pada Pasien Rawat Inap Rumah Sakit Jiwa Daerah Dr. Amino Gondohutomo Semarang Periode 2005 [PDF]

, 2007
Haloperidol and chlorpromazine antipsycotic were used for broad and so long time. That drugs used could shown undesire side effect. Objective of this study was to investigate haloperidol and chlorpromazine side effect, especially was to know relative ...
susilowati, S. (sri)
core  

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Multiple Ascending Doses and Dose Titration of Bexicaserin in Healthy Participants in a Randomized, Double‐Blind, Placebo‐Controlled Study

Clinical Pharmacology in Drug Development, EarlyView.
Abstract Bexicaserin (LP352) is a selective superagonist of the 5‐hydroxytryptamine 2C (5‐HT2C) receptor currently in development for the treatment of seizures that arise from developmental and epileptic encephalopathies. This phase 1, double‐blind, placebo‐controlled multiple ascending dose (MAD) study assessed the safety, tolerability, and ...
Jonathan Williams, Rosa Chan, Chad Orevillo, Gale O'Connell, Dewey McLin, Shikha Polega, Nuggehally R. Srinivas, Randall Kaye   +7 more
wiley   +1 more source

Orthostatic Hypotension and its Relationship with HbA1c Levels in Patients with Diabetes Mellitus

National Journal of Medical Research, 2022
Introduction: For the diagnosis of diabetes mellitus, various tests are available such as FBS (Fasting blood sugar), PPBS ( Post Prandial Blood Sugar), Oral Glucose Tolerance Test, Random Plasma Glucose Test, HBA1c, etc, of which HBA1c is considered to ...
Deep Bavaria, Asmita Rathod, Ankur Patel, Jigisha Chaudhari   +3 more
doaj   +1 more source

Rapidly Progressive Multiple System Atrophy-Cerebellar Type in a 52-Year-Old Woman: Diagnostic Challenges in a Resource-Limited Setting. [PDF]

Clin Case Rep
ABSTRACT Multiple system atrophy (MSA) is a progressive adult‐onset neurodegenerative disorder that manifests as a variable combination of cerebellar, parkinsonian, and autonomic dysfunctions. We report a case of a 52‐year‐old woman who presented with rapidly progressive gait ataxia, dysarthria, orthostatic hypotension, and urinary urgency.
Singh KV, Nimmagadda SP, Panda A, Rohith R, Patel TJ, Gopathoti S, Patel PV, Parmar MP, Mohammed S.   +8 more
europepmc   +2 more sources

A phenomap of TTR amyloidosis to aid diagnostic screening

ESC Heart Failure, Volume 12, Issue 2, Page 1113-1118, April 2025.
Abstract Cardiac amyloidosis due to transthyretin (ATTR) remains an underdiagnosed cause of cardiomyopathy. As awareness of the disease grows and referrals for ATTR increase, clinicians are likely to encounter more atypical forms of the condition in clinical practice.
Alexios S. Antonopoulos, Theodoros Tsampras, George Lazaros, Konstantinos Tsioufis, Charalambos Vlachopoulos   +4 more
wiley   +1 more source

Impairments in hemodynamic responses to orthostasis associated with frailty : results from The Irish Longitudinal Study on Ageing (TILDA) [PDF]

, 2018
Objectives To characterize the relationships between orthostatic blood pressure (BP) and heart rate recovery and frailty in an older population. Design Cross‐sectional study. Setting Two health centers in the Republic of Ireland.
Fan, Chie Wei, Finucane, Ciarán, Kenny, Rose Anne, O’Connell, Matthew, Romero-Ortuno, Roman, Savva, George M.   +5 more
core   +4 more sources

Phenotype characterization of heart failure with preserved ejection fraction in medical device and surgical trials

ESC Heart Failure, EarlyView.
This systematic review identified 24 clinical trials of medical device and surgical interventions for HFpEF, with 16 demonstrating at least safety and feasibility, but little evidence of long‐term benefit. Phenotype‐based responses suggest that certain interventions may benefit specific HFpEF subgroups, yet most trials suffered from heterogeneous ...
Kurdo Araz, Francesco Fioretti, Sara Ladak, Mohammed Obaidan, Javed Butler, Aamir Hameed   +5 more
wiley   +1 more source

Frequency Distribution of Orthostatic Hypotension, Nocturnal Hypertension, and Postprandial Hypotension in Patients with Parkinson's Disease: A Case- Control Study

مجله دانشکده پزشکی اصفهان, 2012
Background: Orthostatic hypotension is a common autonomic dysfunction in Parkinson's disease. Major hypotheses proposed in the etiology of orthostatic hypotension include sympathetic denervation and treatment with dopaminergic drugs.
Ahmad Chitsaz, Mohammad Saadatnia, Maliheh Khalili Bandali   +2 more
doaj  

Nondipping in Parkinson's Disease

Parkinson's Disease, 2011
Objective. The aim of this study was to identify patients with Parkinson's disease who showed loss or decrease of nocturnal blood pressure fall (nondipper patients) as a marker of autonomic dysfunction.
Sita Sommer, Billur Aral-Becher, Wolfgang Jost   +2 more
doaj   +1 more source

Orthostatic Cerebral Hypoperfusion Syndrome (OCHOS)

Frontiers in Aging Neuroscience, 2016
Objective: Orthostatic dizziness without orthostatic hypotension is common but underlying pathophysiology is poorly understood. This study describes orthostatic cerebral hypoperfusion syndrome (OCHOS). OCHOS is defined by: 1) Abnormal orthostatic drop of
Peter eNovak
doaj   +1 more source