Results 61 to 70 of about 308,666 (390)
Cell-penetrating pepducins targeting the neurotensin receptor type 1 relieve pain [PDF]
Pharmacological Research. 104750 (2020), 2020 Pepducins are cell-penetrating, membrane-tethered lipopeptides designed to target the intracellular region of a G protein-coupled receptor (GPCR) in order to allosterically modulate the receptor's signaling output. In this proof-of-concept study, we explored the pain-relief potential of a pepducin series derived from the first intracellular loop of ...
arxiv +1 more source
Supervised Machine-learning Predictive Analytics for Prediction of Postinduction Hypotension
Anesthesiology, 2018 What We Already Know about This Topic The ability to predict postinduction hypotension remains limited and challenging due to the multitude of data elements that may be considered Novel machine-learning algorithms may offer a systematic approach to ...
S. Kendale +3 more
semanticscholar +1 more source
American Journal of Neuroradiology, 2020 SUMMARY: Spontaneous intracranial hypotension is a condition characterized by low CSF volume secondary to leakage through a dural defect with no identifiable cause. Patients classically present with orthostatic headaches, but this symptom is not specific
K. Bond +5 more
semanticscholar +1 more source
Toxins, 2019 Russell’s viper (Daboia russelii) venom causes a range of clinical effects in humans. Hypotension is an uncommon but severe complication of Russell’s viper envenoming. The mechanism(s) responsible for this effect are unclear.
Rahini Kakumanu +5 more
doaj +1 more source
Systemic capillary leak syndrome under general anesthesia: a case report [PDF]
Korean Journal of Anesthesiology, 2014 Systemic capillary leak syndrome (SCLS) is very rare and lethal disease and only 150 cases have been reported after the first publication of its report in 1960 by Clarkson.
Eui-Kyun Jeong +4 more
doaj +1 more source
Adaptive Semi-Supervised Inference for Optimal Treatment Decisions with Electronic Medical Record Data [PDF]
arXiv, 2022 A treatment regime is a rule that assigns a treatment to patients based on their covariate information. Recently, estimation of the optimal treatment regime that yields the greatest overall expected clinical outcome of interest has attracted a lot of attention. In this work, we consider estimation of the optimal treatment regime with electronic medical
arxiv
Critical Care, 2020 Background The postoperative period is critical for a patient’s recovery, and postoperative hypotension, specifically, is associated with adverse clinical outcomes and significant harm to the patient.
N. Smischney +6 more
semanticscholar +1 more source
Clinical Phenotyping of Long COVID Patients Evaluated in a Specialized Neuro‐COVID Clinic
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To report Long COVID characteristics and longitudinal courses of patients evaluated between 4/14/21–4/14/22 at the University of Pennsylvania Neurological COVID Clinic (PNCC), including clinical symptoms, neurological examination findings, and neurocognitive screening tests from a standardized PNCC neurological evaluation approach ...
Luana D. Yamashita +7 more
wiley +1 more source
Marine Drugs, 2011 This study aimed to investigate the cardiovascular effects elicited by Dictyota pulchella, a brown alga, using in vivo and in vitro approaches. In normotensive conscious rats, CH2Cl2/MeOH Extract (CME, 5, 10, 20 and 40 mg/kg) from Dictyota pulchella ...
Isac A. Medeiros +9 more
doaj +1 more source
Heart Vessels and Transplantation, 2022 On the stage of left atrial percutaneous procedures a number of acute complications and their management have been described. In the current brief report, coronary air embolism, its acute manifestations, differential diagnosis and outcomes were presented
Luis Antonio Arabia +1 more
doaj +1 more source