Results 161 to 170 of about 202,089 (261)

Inhibitory neurotransmission in frontostriatal circuitry: implications for psychomotor and vegetative symptoms in depressive episodes. [PDF]

BMC Psychiatry
Steinholtz L, Persson J, Thörnblom E, Wall A, Lubberink M, Fällmar D, Bodén R.   +6 more
europepmc   +1 more source

Neonatal seizures and GABAergic drugs: Scylla and Charybdis?

Epilepsia Open, EarlyView.
Abstract Neonates have a high incidence of seizures that are frequently difficult to control with conventional first‐line anti‐seizure medications, which are gamma‐aminobutyric acid (GABA) agonists. The reasons for this clinical problem are multifold but are likely related to the unique physiology of the immature nervous system. Specifically, the early
Kerry W. Thompson, Lucie Suchomelova, Claude G. Wasterlain   +2 more
wiley   +1 more source

Regionalization of the Developing Hypothalamus: The Prosomeric and Tripartite Models. [PDF]

Cells
Kapsimali M.
europepmc   +1 more source

Epilepsy surgery through a reproductive lifespan lens

Epilepsia, EarlyView.
Aisha A. Abdulrazaq, Dorothee Kasteleijn‐Nolst Trenite, Torbjörn Tomson   +2 more
wiley   +1 more source

The gut microbiome and drug‐resistant epilepsy: Microbiome–antiseizure medication interactions and implications for pharmacoresistance

Epilepsia Open, EarlyView.
Abstract Drug‐resistant epilepsy (DRE) affects approximately one‐third of patients with epilepsy and represents a major unmet clinical need. While traditional hypotheses of pharmacoresistance have focused on alterations in drug targets, efflux transporter overexpression, and intrinsic disease severity, the gut microbiome has recently emerged as a ...
Khaled Zammar, Majd A. AbuAlrob, Musab Ali, Simona Lattanzi, Boulenouar Mesraoua   +4 more
wiley   +1 more source

Short-term environmental enrichment modulates brain region-specific redox responses in adolescent female mice. [PDF]

Front Aging Neurosci
de Sousa Fernandes MS, Kanashiro A, Ramos TL, Pereira DD, de Souza VL, Lagranha CJ, Tüfekci S, Yagin B, Alkhamees NH, Souto FO.   +9 more
europepmc   +1 more source

Shared molecular pathways in pediatric genetic epilepsies: Insights from a single‐center cohort of 80 patients

Epilepsia Open, EarlyView.
Abstract Objective Genetic epilepsies in childhood are highly heterogeneous, and approaches to identify shared biological mechanisms across distinct genetic etiologies remain limited. We aimed to investigate whether genes associated with pediatric genetic epilepsies in our heterogeneous cohort converge on common functional pathways.
Laura Hecher, Mathias Woidy, Franziska Plein, Tatjana Bierhals, Leonie von Elsner, Theresia Herget, Maja Hempel, Fanny Kortüm, Lev Grinstein, Julia V. Cramer, Jessika Johannsen, Jonas Denecke   +11 more
wiley   +1 more source

Hypothalamic Inflammaging: A Central Driver of Type 2 Diabetes Mellitus and Metabolic Disease in Aging. [PDF]

Diabetes Metab J
Lyoo SH, Kim KH, Kim KW.
europepmc   +1 more source