Results 111 to 120 of about 6,405,584 (270)

Mechanisms underlying hypothermia-induced cardiac contractile dysfunction.

open access: yesAmerican Journal of Physiology. Heart and Circulatory Physiology, 2010
Rewarming patients after profound hypothermia may result in acute heart failure and high mortality (50-80%). However, the underlying pathophysiological mechanisms are largely unknown. We characterized cardiac contractile function in the temperature range
Young‐Soo Han   +7 more
semanticscholar   +1 more source

The effects and mechanisms of stem cells and exosomes on neurological function protection and recovery after ischemic stroke

open access: yesNeuroprotection, EarlyView.
Effect and mechanism of stem cells and exosomes therapy in ischemic stroke. The effect and mechanism include protection of neuron and glial cells, repairment of nerve vascular unit, reduction of inflammation response, restoration of white matter integrity, reconstruction of neural circuit, replacement of neurons and glial cells, and anti‐ferroptosis ...
Weihong Du   +4 more
wiley   +1 more source

Molecular Mechanisms Underlying Hypothermia-Induced Neuroprotection

open access: yesStroke Research and Treatment, 2010
Stroke is a dynamic event in the brain involving heterogeneous cells. There is now compelling clinical evidence that prolonged, moderate cerebral hypothermia initiated within a few hours after severe ischemia can reduce subsequent neuronal death and ...
Y. Shintani, Yasuko Terao, H. Ohta
semanticscholar   +1 more source

Ligand Recognition and Function of TAARs

open access: yesSensory Neuroscience, EarlyView.
The trace amine‐associated receptor (TAAR) family represents a highly conserved group of G protein‐coupled receptors (GPCRs) in vertebrates. TAARs specifically bind to different amine ligands and mediate a variety of physiological and behavioral processes.
Kang‐Ying Qian   +3 more
wiley   +1 more source

Hypothermia Induced Impairment of Platelets: Assessment With Multiplate vs. ROTEM-An In Vitro Study. [PDF]

open access: yesFront Physiol, 2022
Wallner B   +7 more
europepmc   +1 more source

Comprehensive Osteosarcoma Treatment with Multifunctional Composite Hydrogels Enabling Combined Photothermal Cancer Ablation and Osteoinductive Tissue Regeneration

open access: yesSmall Methods, EarlyView.
This study presents a comprehensive strategy for treating osteosarcoma and promoting bone tissue regeneration using a multifunctional composite hydrogel composed of mineralized fibers with polyphenols. Furthermore, the biomaterial effectively mitigates the degenerative microenvironment including oxidative stress that develops after tumor ablation. This
Hayeon Byun   +8 more
wiley   +1 more source

Induced hypothermia for trauma-related ARDS

open access: yesIndian Journal of Critical Care Medicine, 2015
We report a case of 27-year-old male with lung contusions related acute respiratory distress syndrome (ARDS) managed by ARDSNet guidelines and additional hypothermia. On 4(th) day, post trauma partial pressure of oxygen dropped to 38 mm of mercury (Hg), not improving even on high positive end-expiratory pressure of 18 cm water (H2O), inverse ratio ...
Gagandeep Dhillon   +3 more
openaire   +3 more sources

Neural mechanisms and clinical features of anti‐influenza drug‐related psychiatric adverse events

open access: yesVIEW, EarlyView.
Anti–influenza drugs, while essential, have been increasingly associated with psychiatric adverse events (pAEs). Our study systematically investigated these pAEs by utilizing large pharmacovigilance databases and animal models, thereby revealing key clinical features and underlying neural mechanisms.
Anqi Lin   +9 more
wiley   +1 more source

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