Results 101 to 110 of about 244,003 (397)

Accidental hypothermia–an update

Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine, 2016
BackgroundThis paper provides an up-to-date review of the management and outcome of accidental hypothermia patients with and without cardiac arrest.MethodsThe authors reviewed the relevant literature in their specialist field.
P. Paal, L. Gordon, G. Strapazzon, Monika Brodmann Maeder, G. Putzer, B. Walpoth, M. Wanscher, Doug Brown, M. Holzer, G. Broessner, H. Brugger   +10 more
semanticscholar   +1 more source

Generating golden Syrian hamsters with conditional alleles via zygote microinjection of CRISPR/Cas9

Animal Models and Experimental Medicine, EarlyView.
We established the first conditional knockout (cKO) model in the golden Syrian hamster by CRISPR/Cas9‐mediated genome editing. Cas9 protein, two sgRNAs, and a donor plasmid carrying loxP‐flanked exon 2 of the ApoF gene were microinjected into one‐cell embryos. The floxed allele was efficiently generated (up to 27%) and transmitted through the germline.
Wei Chen, Xu Zhang, Rui Fan, Xia Li, Feifei Guan, Gefan Wan, Weining Kong, Xiaolong Qi, Shuo Pan, Sijing Shi, Yuanlong Su, Shan Gao, Wei Huang, Xunde Xian, Jiangning Liu, Yuhui Wang, Yuanwu Ma   +16 more
wiley   +1 more source

Back Again to the Future: A New Era for Cerebroprotection

Annals of Neurology, EarlyView.
Cerebroprotection is a fresh framework for designing neurological therapy that targets glia and vascular cells, in addition to neurons. In the future, successful cerebroprotection will involve targeting all elements of the neurovascular unit. Preclinical trials must include functional outcomes, as well as lesion morphometry.
Patrick Lyden
wiley   +1 more source

Birthing practices of traditional birth attendants in South Asia in the context of training programmes [PDF]

, 2010
Traditional Birth Attendants (TBA) training has been an important component of public health policy interventions to improve maternal and child health in developing countries since the 1970s.
Adamson, P., Armstrong, P., Bajpai, S., Bajpai, S., Bajpai, S., Banerjee, A., Banerjee, A., Bhardwaj, N., Bhutta, Z.A., Brown, H., Carpenter, J.P., Chaudhury, N., Chirmulay, D., Dalmiya, V., Das, B.K., Fatmi, Z., Gavin Turrell, Guha, S., Helen Johnson, Hitesh, J., Hota, P.K., Isenalumbe, A.E., Jeffery, R., Jeffery, R., Jennifer Fraser, John, T.J., Kausar, F., Khan, M.E., Khandekar, J., Kitzinger, S., Kumar, R., Lak, D., Lettenmaier, C., Maitra, K., Mashelkar, R.A., Mathews, Z., Mathews, Z., Mesko, N., Misra, R., Nagadeve, D.A., Nandan, D., Nandan, D., Pfitzer, A., Pinto, S., Raina, N., Ram, K., Rodgers, K.A., Saeed Ali, T., Shariff, A., Sheela Saravanan, Smale, M., Smith, D., Smith, D., Smith, D., Sreeramareddy, C.T., Srivastava, S.P., Unnithan, M.K., Van Hollen, C.   +57 more
core   +2 more sources

Perioperative Neuroprotection with Systemic Hypothermia During Carotid Endarterectomy

Общая реаниматология
Prevention of brain injury during carotid endarterectomy (CEA) remains a significant challenge. Moderate controlled systemic hypothermia may serve as a potential neuroprotective measure during these procedures.Aim of the study.
Alexey A. Syrovatsky, Ionas S. Simutis, Alexey V. Svetlikov, Konstantin M. Lebedinsky, Alexey N. Shcheglov, Vyacheslav A. Ratnikov, Daria E. Reznichek, Evgenia V. Khaldina   +7 more
doaj   +1 more source

Akt1-mediated CPR cooling protection targets regulators of metabolism, inflammation and contractile function in mouse cardiac arrest.

PLoS ONE, 2019
Therapeutic hypothermia initiated during cardiopulmonary resuscitation (CPR) in pre-clinical studies appears to be highly protective against sudden cardiac arrest injury.
Jing Li, Xiangdong Zhu, Huashan Wang, Chunpei Lee, Sy-Jou Chen, Yuanyu Qian, Mei Han, Ryan Bunney, David G Beiser, Terry L Vanden Hoek   +9 more
doaj   +1 more source

Tri‐Modal Anticancer Strategies with Doxorubicin‐Loaded Iron Oxide Nanoparticles Integrating Chemo and Magneto‐Photothermal Therapeutic Effects

Advanced NanoBiomed Research, EarlyView.
Maghemite nanoparticles functionalized with doxorubicin enable synergistic chemo‐magneto‐photothermal therapy. Combining pH‐sensitive drug release with localized heating at clinically relevant low doses enhances tumor cell death while minimizing toxicity.
Rosalía López‐Méndez, Nuria Lafuente‐Gómez, Eva Céspedes, Mónica Dhanjani, Marina París‐Ogáyar, Francisco José Terán, Aida Serrano, Julio Camarero, Gorka Salas, Claire Wilhelm, Álvaro Somoza, Ana Espinosa   +11 more
wiley   +1 more source

Neonatal hypothermia and associated factors among neonates admitted to neonatal intensive care unit of public hospitals in Addis Ababa, Ethiopia

BMC Pediatrics, 2018
BackgroundNeonatal hypothermia is a worldwide problem and an important contributing factor for Neonatal morbidity and mortality especially in developing countries. High prevalence of hypothermia has been reported from countries with the highest burden of
B. Demissie, B. Abera, T. Chichiabellu, F. H. Astawesegn   +3 more
semanticscholar   +1 more source

Anatolian ground squirrel (Spermophilus xanthoprymnus) retina: Comparative expression of synaptophysin, NeuN, calbindin‐D28k, parvalbumin, glial fibrillary acidic protein, and Iba‐1 during pre‐hibernation and hibernation

The Anatomical Record, EarlyView.
Abstract Hibernation induces significant molecular and cellular adaptations in the retina to maintain function under reduced metabolic conditions. This study aimed to investigate the expression of neuronal, synaptic, and glial markers in the retina of Spermophilus xanthoprymnus during pre‐hibernation and hibernation periods using immunohistochemical ...
Mehmet Özbek, Feyzullah Beyaz, Mustafa Öztop, Harun Karaca, Ahmet Cabir, Begüm Fatma Kiryar   +5 more
wiley   +1 more source

Oklahoma Heart Hospital: Clinician Leaders Establish Culture of Quality [PDF]

, 2009
Describes strategies for a culture of quality, including a flat organizational structure, optimal nurse experience and ratios, standardization through care sets, technology-enabled feedback and assessment, and continuous improvement through new ...
Sharon Silow-Carroll
core