ANZ Journal of Surgery, EarlyView.Across 11 observational studies comprising 6 471 577 patients, the pooled incidence of ischaemic optic neuropathy after cardiac surgery was approximately 1.5 cases per 10 000 procedures. Coronary artery disease, peripheral vascular disease and anaemia were associated with increased odds of ION, although these findings should be interpreted in the ...
Daud Mutahar +11 more
wiley +1 more source
Dual acellular subnormothermic machine perfusion for enhanced uterus preservation in a swine model
Acta Obstetricia et Gynecologica Scandinavica, EarlyView.In a porcine uterus transplantation model, subnormothermic machine perfusion reduced graft edema and better‐preserved post‐reperfusion contractility than static cold storage, highlighting its potential for uterus preservation, assessment, and future graft‐conditioning applications.
Lucile Cabanel +13 more
wiley +1 more source
The Osmium Isotope Signature of Phanerozoic Large Igneous Provinces
Geophysical Monograph Series, Page 229-246., 2021 Exploring the links between Large Igneous Provinces and dramatic environmental impact
An emerging consensus suggests that Large Igneous Provinces (LIPs) and Silicic LIPs (SLIPs) are a significant driver of dramatic global environmental and biological changes, including mass extinctions.
Alexander J. Dickson +2 more
wiley +3 more sources
Artificial Organs, EarlyView.A novel quantitative method using Indocyanine Green (ICG) fluorescence image for assessing organ viability during hypothermic oxygenated machine perfusion (HOPE), specifically focusing on homogeneous flow distribution analyzed with the gray‐scale level co‐occurrence matrix (GLCM) method, can predict portal vein resistance induced by ischemic ...
Yuga Okazawa +10 more
wiley +1 more source
Monitoring Mitochondrial Function With High‐Resolution Respirometry During Ex‐Situ Heart Perfusion
Artificial Organs, EarlyView.Normothermic ESHP preserves mitochondrial respiratory function over 6 h in a porcine model (n = 6): OXPHOS capacities across NADH‐, fatty‐acid‐, and succinate‐linked pathways remain stable, with reduced cytochrome‐c control efficiency indicating improved outer‐membrane integrity. HRR provides a rapid, actionable readout for organ assessment.
Lukas Stastny +12 more
wiley +1 more source
Experimental Extracorporeal Circulation System: A Pilot Study in Rats
Artificial Organs, EarlyView.A miniature extracorporeal circulation (ECC) system was developed for reproducible rodent studies. This system incorporates an integrated heat exchanger and a silicone membrane oxygenator within a double‐lumen circuit, resulting in an ultralow priming volume of < 1.5 mL.
Akira T. Kawaguchi +7 more
wiley +1 more source
Prevalence of hypothermia prior to trauma center arrival and associated mortality in pediatric traumatic brain injury patients. [PDF]
Pediatr Surg IntBell TM +4 more
europepmc +1 more source
Progress Toward a Portable Artificial Lung: A Systematic Review
Artificial Organs, EarlyView.Eight portable respiratory assist devices were identified. The CE‐marked MobyBox and the FDA‐approved Breethe OXY‐1 system are in clinical use. Each device is substantially minimized to allow ambulation, but further work is required to address challenges related to anticoagulant management and safe mobilization. Created in BioRender. Svendsen, A. (2026)
Maja Munk Svendsen +5 more
wiley +1 more source
The ICECAP Study Did Not Find Evidence for Better Outcomes With Prolonged Cooling After Out-Of-Hospital Cardiac Arrest. [PDF]
Acta Anaesthesiol ScandAneman A, Nielsen N, Skrifvars MB.
europepmc +1 more source
Artificial Organs, EarlyView.The immunogenicity of donor kidneys on NMP can be studied using monocyte‐derived dendritic cells. Incubation with perfusate showed an anti‐inflammatory dendritic cell phenotype and function that suggests the release of an anti‐inflammatory factor or factors during NMP. ABSTRACT Background The immunomodulatory activity of normothermic machine perfusion (
Laura W. D. Knijff +8 more
wiley +1 more source