Results 91 to 100 of about 10,248,752 (301)
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
An Adaptive Fault-Tolerant Federated Kalman Filter for a Multi-Sensor Integrated Navigation System
SensorsTo achieve autonomous and reliable all-weather cross-domain aerospace navigation, this study proposes an adaptive fault-tolerant federated Kalman filter (AFTFKF) for an INS/SRNS/CNS integrated navigation system to enhance system robustness against ...
Guangle Gao +3 more
doaj +1 more source
Investigation of Shrinkage of Concrete Mixtures Used for Bridge Construction in Lithuania
The Baltic Journal of Road and Bridge Engineering, 2011 The present paper reports results of the investigation on shrinking of the concrete mixture which is often used for casting the new bridges. The study is based on the experimental results obtained in three research projects which were performed under ...
Viktor Gribniak +5 more
doaj +1 more source
Are Experts Well-Calibrated? An Equivalence-Based Hypothesis Test. [PDF]
Entropy (Basel), 2022 Dharmarathne G, Hanea AM, Robinson A.
europepmc +1 more source
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
A Hypothesis Test for the Long-Term Calibration in Rating Systems with Overlapping Time Windows
RisksWe present a statistical test for the long-term calibration in rating systems that can deal with overlapping time windows as required by the guidelines of the European Banking Authority (EBA), which apply to major financial institutions in the European ...
Patrick Kurth, Max Nendel, Jan Streicher
doaj +1 more source
Determining sample size for progression criteria for pragmatic pilot RCTs: the hypothesis test strikes back! [PDF]
Pilot Feasibility Stud, 2021 Lewis M +5 more
europepmc +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Journal of the Royal Statistical Society Series B: Statistical Methodology, 1984 SUMMARY The concept of multiple comparisons between a set of competing hypotheses is examined. A statistic is developed for testing a maintained hypothesis against a series of separate alternatives. This statistic is an extension of the binary Cox test.
openaire +2 more sources
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source