Results 171 to 180 of about 997,357 (330)
FEBS Open Bio, EarlyView.Osimertinib reduces angiogenesis and PDL1 expression in in ovo tumors, transforming them into ‘cold tumors’ with lower immune activity. Anatomopathological and transcriptomic analyses highlight its therapeutic impact on tumor biology. This study underscores osimertinib's potential to reshape the tumor microenvironment and provides insights into its ...
David Barthélémy +14 more
wiley +1 more source
The anterior nucleus of the thalamus plays a role in the epileptic network
Annals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 2010-2024, December 2022., 2022 Abstract Objectives We investigated both the metabolic differences and interictal/ictal discharges of the anterior nucleus of the thalamus (ANT) in patients with epilepsy to clarify the relationship between the ANT and the epileptic network. Methods Nineteen patients with drug‐resistant epilepsy who underwent stereoelectroencephalography were studied ...
Hao Yan +9 more
wiley +1 more source
bootRanges: flexible generation of null sets of genomic ranges for hypothesis testing. [PDF]
Bioinformatics, 2023 Mu W +5 more
europepmc +1 more source
The Impact of International Factors on U. S. Inflation: An Empirical Test of the Currency Substitution Hypothesis [PDF]
, 1986 Dallas S. Batten, R. W. Hafer
openalex +1 more source
Red blood cells could protect miRNAs from degradation or loss thanks to Argonaute 2 binding
FEBS Open Bio, EarlyView.The present work investigates the presence and the stability of miRNAs into RBCs, both native and engineered. The observed stability is due to the Ago2 bound resulting in minimal RISC. Indeed, if the miRNA‐Ago2 complex is present, miRNAs are protected from release or degradation and they are biologically active. Thus, RBCs can act as miRNA carriers for
Elena Perla +4 more
wiley +1 more source
Iterative hypothesis testing in HIV vaccine research: moving towards success. [PDF]
J Int AIDS Soc, 2023 Anklesaria P, Russell ND.
europepmc +1 more source
FEBS Open Bio, EarlyView.This study reports the upregulation of ELMO1 and GPR141 in human Fuchs' endothelial corneal dystrophy (FECD) corneal endothelium and ultraviolet A‐induced FECD mice model. A genetic association of an intergenic single nucleotide polymorphism rs918980 present between both genes is observed with FECD in the Indian population.
Susmita Sharma +3 more
wiley +1 more source
Aberrant Responding in Hypothesis Testing: A Threat to Validity or Source of Insight? [PDF]
Behav Sci (Basel)Sideridis G, Alghamdi MH.
europepmc +1 more source
Simultaneous hypothesis testing for multiple competing risks in comparative clinical trials. [PDF]
Stat Med, 2023 Wen J, Wang MC, Hu C.
europepmc +1 more source