Results 181 to 190 of about 2,690,705 (301)

Surrogate data for hypothesis testing of physical systems

, 2018
Gemma Lancaster, Dmytro Iatsenko, Aleksandra Pidde, Valentina Ticcinelli, Aneta Stefanovska   +4 more
openalex   +1 more source

The photoswitchable cannabinoid azo‐HU308 enables optical control of Ca2+ dynamics in INS‐1 β‐cells via off‐target effects on TRPC channels

FEBS Open Bio, EarlyView.
Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley   +1 more source

Detecting implicit biases of large language models with Bayesian hypothesis testing. [PDF]

Sci Rep
Si S, Jiang X, Su Q, Carin L.
europepmc   +1 more source

Hypothesis testing by convex optimization

, 2013
Alexander Goldenshluger, A. Juditski, Arkadi Nemirovski   +2 more
openalex   +1 more source

SmallTalk: a novel small‐sized fusion tag for peptide expression and purification

FEBS Open Bio, EarlyView.
The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq, Nestor G. Casillas‐Vega, Alma Gomez‐Loredo, Xristo Zarate   +3 more
wiley   +1 more source

Thinking in opposites improves hypothesis testing performance in Wason's rule-discovery task. [PDF]

Mem Cognit
Branchini E, Bianchi I, Burro R.
europepmc   +1 more source

Peer Review #1 of "Probabilistic biomechanical finite element simulations: whole-model classical hypothesis testing based on upcrossing geometry (v0.1)"

, 2016
A Erdemir
openalex   +1 more source

Naked cuticle is essential for Drosophila wing development beyond Wingless signaling

FEBS Open Bio, EarlyView.
Naked cuticle (Nkd), a Wnt signaling inhibitor, assumes extensive roles in Drosophila wing development. Overexpressing Nkd causes smaller, crumpled wings, while also perturbing multiple signaling pathways and developmental genes. A specific region (R1S) is critical for Nkd's function as a signaling integrator, offering new insights for studying its ...
Rui Wang, Ping Wang
wiley   +1 more source

The <i>Carpiodes</i> Conundrum: Molecular Hypothesis Testing Informs Conservation Applications for Carpsuckers (Catostomidae: <i>Carpiodes</i>) in Texas and Beyond. [PDF]

Ecol Evol
Roberts HC, Bean PT, Keith KD, Conway KW, Perkin JS.   +4 more
europepmc   +1 more source

Decision curve analysis: confidence intervals and hypothesis testing for net benefit. [PDF]

Diagn Progn Res, 2023
Vickers AJ, Van Claster B, Wynants L, Steyerberg EW.   +3 more
europepmc   +1 more source