Results 181 to 190 of about 16,679,614 (365)

Decision curve analysis: confidence intervals and hypothesis testing for net benefit. [PDF]

open access: yesDiagn Progn Res, 2023
Vickers AJ   +3 more
europepmc   +1 more source

Targeting of PTP4A3 overexpression sensitises HGSOC cells towards chemotherapeutic drugs

open access: yesMolecular Oncology, EarlyView.
In HGSOC with normal KRAS expression, high PTP4A3 expression regulates autophagy activation. Conversely, in HGSOC with high KRAS expression, KRAS dictates autophagy control, and PTP4A3 is not required. When high PTP4A3 expression is inhibited, HGSOC cells are preferentially sensitised towards DNA‐damaging agents.
Ana López‐Garza   +3 more
wiley   +1 more source

HiCognition: a visual exploration and hypothesis testing tool for 3D genomics. [PDF]

open access: yesGenome Biol, 2023
Langer CCH   +3 more
europepmc   +1 more source

What’s in a p? Reassessing best practices for conducting and reporting hypothesis-testing research

open access: yesJournal of International Business Studies, 2017
K. Meyer   +2 more
semanticscholar   +1 more source

Olaparib synergy screen reveals Exemestane induces replication stress in triple‐negative breast cancer

open access: yesMolecular Oncology, EarlyView.
Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh   +5 more
wiley   +1 more source

bootRanges: flexible generation of null sets of genomic ranges for hypothesis testing. [PDF]

open access: yesBioinformatics, 2023
Mu W   +5 more
europepmc   +1 more source

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