Most autophagic cell death studies lack evidence of causality
Of 104 studies claiming autophagic cell death (ACD), only 13 demonstrated both causality and exclusion of apoptosis to confirm true ACD. Most studies relied on correlation‐level data or measured autophagy in isolation, revealing pervasive methodological shortcomings.
Ali Burak Özkaya, Yasmin Ghaseminejad
wiley +1 more source
Statistical inference on nonparametric regression model with approximation of Fourier series function: Estimation and hypothesis testing. [PDF]
Ramli M, Budiantara IN, Ratnasari V.
europepmc +1 more source
Combined Tests of The Fisher and Expectation Hypothesis
Raul Eduardo Garcia
openalex +2 more sources
The reliability of a hypothesis generation and testing task [PDF]
Michael B. Donnelly+2 more
openalex +1 more source
Statins, identified via the Comparative Toxicogenomics Database, promote monocytic differentiation and apoptosis in non‐APL AML cells by upregulating DPYSL2A through a KLF4‐dependent pathway. Mevalonate supplementation reversed these effects, indicating involvement of the mevalonate pathway.
Mina Noura+7 more
wiley +1 more source
RegionScan: a comprehensive R package for region-level genome-wide association testing with integration and visualization of multiple-variant and single-variant hypothesis testing. [PDF]
Brossard M+6 more
europepmc +1 more source
Spinal Cord Abnormalities in Early Pediatric Multiple Sclerosis
ABSTRACT Spinal cord lesions and atrophy in the cervical region are common in adult multiple sclerosis (MS) and correlate with disability. Whether similar abnormalities occur in pediatric MS patients is largely unknown. Clinical and MRI evaluations were performed in 38 pediatric MS patients and 13 healthy controls (HC).
Monica Margoni+7 more
wiley +1 more source
Stochastic resonance noise modified decision solution for binary hypothesis-testing under minimax criterion. [PDF]
Yang T, Liu L, Xiang Y, Liu S, Zhang W.
europepmc +1 more source
Towards testing the Dutch hypothesis from childhood [PDF]
I. Annesi, F. Kauffmann
openalex +1 more source
Detecting rs‐fMRI Networks in Disorders of Consciousness: Improving Clinical Interpretability
ABSTRACT Background Preserved resting‐state functional MRI (rs‐fMRI) networks are typically observed in Disorders of Consciousness (DOC). Despite the widespread use of rs‐fMRI in DOC, a systematic assessment of networks is needed to improve the interpretability of data in clinical practice.
Jean Paul Medina Carrion+15 more
wiley +1 more source