Results 61 to 70 of about 2,680,981 (273)

Bayesian Hypothesis Testing for Block Sparse Signal Recovery

, 2015
This letter presents a novel Block Bayesian Hypothesis Testing Algorithm (Block-BHTA) for reconstructing block sparse signals with unknown block structures.
Korki, Mehdi, Zayyani, Hadi, Zhang, Jingxin   +2 more
core   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

STATISTICAL HYPOTHESIS TESTING USING FUZZY LINGUISTIC VARIABLES [PDF]

Fiabilitate şi Durabilitate, 2012
This work proposes a fuzzy statistical test of fuzzy hypotheses usinglinguistic variables. The method is based on Zadeh’s principle: the fuzzy population mean in the null hypothesis is converted to fuzzy numbers using conversion scales proposed by Chen ...
Iuliana Carmen BĂRBĂCIORU
doaj  

Hypothesis Testing based Intrinsic Evaluation of Word Embeddings

, 2017
We introduce the cross-match test - an exact, distribution free, high-dimensional hypothesis test as an intrinsic evaluation metric for word embeddings.
Gurnani, Nishant
core   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Testing Happiness Hypothesis among the Elderly

Cuadernos de Economía, 2008
We use a rich data set that allows us to test different happiness hypotheses employing four methodological approaches. We find that older people in Uruguay have a tendency to report themselves happy when they are married, when they have higher standards ...
Rossi Máximo, Ferrés Daniel, Cid Alejandro   +2 more
doaj  

Bayesian alternatives to null hypothesis significance testing in biomedical research: a non-technical introduction to Bayesian inference with JASP

BMC Medical Research Methodology, 2020
Background Although null hypothesis significance testing (NHST) is the agreed gold standard in medical decision making and the most widespread inferential framework used in medical research, it has several drawbacks.
Riko Kelter
doaj   +1 more source

Multiple Hypothesis Testing

Journal of the Royal Statistical Society Series B: Statistical Methodology, 1984
SUMMARY The concept of multiple comparisons between a set of competing hypotheses is examined. A statistic is developed for testing a maintained hypothesis against a series of separate alternatives. This statistic is an extension of the binary Cox test.
openaire   +2 more sources

A Linear Programming Approach to Sequential Hypothesis Testing

, 2015
Under some mild Markov assumptions it is shown that the problem of designing optimal sequential tests for two simple hypotheses can be formulated as a linear program.
Fauss, Michael, Zoubir, Abdelhak M.
core   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source