Results 61 to 70 of about 2,698,578 (273)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

STATISTICAL HYPOTHESIS TESTING USING FUZZY LINGUISTIC VARIABLES [PDF]

open access: yesFiabilitate şi Durabilitate, 2012
This work proposes a fuzzy statistical test of fuzzy hypotheses usinglinguistic variables. The method is based on Zadeh’s principle: the fuzzy population mean in the null hypothesis is converted to fuzzy numbers using conversion scales proposed by Chen ...
Iuliana Carmen BĂRBĂCIORU
doaj  

Recent developments towards optimality in multiple hypothesis testing

open access: yes, 2006
There are many different notions of optimality even in testing a single hypothesis. In the multiple testing area, the number of possibilities is very much greater.
Shaffer, Juliet Popper
core   +2 more sources

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Testing Happiness Hypothesis among the Elderly

open access: yesCuadernos de Economía, 2008
We use a rich data set that allows us to test different happiness hypotheses employing four methodological approaches. We find that older people in Uruguay have a tendency to report themselves happy when they are married, when they have higher standards ...
Rossi Máximo   +2 more
doaj  

Bayesian alternatives to null hypothesis significance testing in biomedical research: a non-technical introduction to Bayesian inference with JASP

open access: yesBMC Medical Research Methodology, 2020
Background Although null hypothesis significance testing (NHST) is the agreed gold standard in medical decision making and the most widespread inferential framework used in medical research, it has several drawbacks.
Riko Kelter
doaj   +1 more source

Hypothesis testing for Gaussian states on bosonic lattices

open access: yes, 2008
The asymptotic state discrimination problem with simple hypotheses is considered for a cubic lattice of bosons. A complete solution is provided for the problems of the Chernoff and the Hoeffding bounds and Stein's lemma in the case when both hypotheses ...
Davies E. B.   +5 more
core   +3 more sources

Multiple Hypothesis Testing

open access: yesJournal of the Royal Statistical Society Series B: Statistical Methodology, 1984
SUMMARY The concept of multiple comparisons between a set of competing hypotheses is examined. A statistic is developed for testing a maintained hypothesis against a series of separate alternatives. This statistic is an extension of the binary Cox test.
openaire   +2 more sources

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

HYPOTHESIS TESTING ON STRUCTURAL COMPARATIVE CALIBRATION MODEL

open access: yesPesquimat, 2014
.- In this work study statistic inference on comparative calibration model introduced for Barnett [1]. Consider hypothesis testing in structural comparative calibration model presented in Theobald and Mallison [4].
Oiga Lidia Solano Dávíla
doaj   +1 more source

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