Results 61 to 70 of about 1,010,534 (310)
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Replication of null results: Absence of evidence or evidence of absence?
eLifeIn several large-scale replication projects, statistically non-significant results in both the original and the replication study have been interpreted as a ‘replication success.’ Here, we discuss the logical problems with this approach: Non-significance
Samuel Pawel +3 more
doaj +1 more source
The assessment centre: testing the fairness hypothesis
SA Journal of Industrial Psychology, 1994 Accumulated international research reveals that assessment centre technology appears to be reasonably 'fair' based on race, sex, and age. Similar research on the assessment centre in South Africa is mostly unknown and/or un-documented. The sample of this
D. N. Hurst, J. A. E. Charoux
doaj +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Statistical group comparison of diffusion tensors via multivariate hypothesis testing
, 2007 Diffusion tensor imaging (DTI) provides a powerful tool for identifying white matter (WM) alterations in clinical populations. The prevalent method for group-level analysis of DTI is statistical comparison of the diffusion tensor fractional anisotropy ...
Wisco, J.J. +3 more
core +1 more source
Hypothesis Testing the Circuit Hypothesis in LLMs
Advances in Neural Information Processing Systems 37Code available here: https://github.com/blei-lab ...
Claudia Shi +7 more
openaire +3 more sources
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Hypothesis Testing in Weighted Distributions
Journal of Mathematical Extension, 2008 There are many situations in which experiments are not available or data are recorded from the population proportion to a nonnegative function called weight function. In a such situations the classical methods for inferencing about unknown parameters
S. M. R. Alavi, R. Chinipardaz and A. R. Rasekh
doaj
Probability, clinical decision making and hypothesis testing
Industrial Psychiatry Journal, 2009 Few clinicians grasp the true concept of probability expressed in the ′P value.′ For most, a statistically significant P value is the end of the search for truth. In fact, the opposite is the case.
A Banerjee, S L Jadhav, J S Bhawalkar
doaj +1 more source
Hypothesis testing in biogeography
Trends in Ecology & Evolution, 2011 Often, biogeography is applied only as a narrative addition to phylogenetic studies and lacks scientific rigour. However, if research questions are framed as hypotheses, biogeographical scenarios become testable. In this review, we explain some problems with narrative biogeography and show how the use of explicit hypotheses is changing understanding of
Crisp, MD, Trewick, SA, Cook, LG
openaire +5 more sources