Results 111 to 120 of about 116,837,064 (272)
Advanced Science, EarlyView.Single‐cell mechanomics demonstrates that pharmacological perturbation changes cytoskeletal and cortical structure, suppressing cancer cell invasiveness. By integrating atomic force microscopy (AFM)‐based cortical measurements with stimulated emission depletion (STED)‐resolved adhesion and cytoskeletal organization, this approach identifies nanoscale ...
Minhee Ku +4 more
wiley +1 more source
"Testing for the Null Hypothesis of Cointegration with Structural Breaks" [PDF]
In this paper we propose residual-based tests for the null hypothesis of cointegration with structural breaks against the alternative of no cointegration.
Eiji Kurozumi, Yoichi Arai
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Advanced Science, EarlyView.ZBTB11 is identified as an oncogenic transcription factor that activates FBXO28 in breast cancer. FBXO28 promotes K48‐linked ubiquitination and degradation of MST1, suppressing Hippo signaling and enhancing epithelial–mesenchymal transition and metastasis. This transcription‐to‐ubiquitination cascade defines a prognostic biomarker axis and highlights a
An Xu +10 more
wiley +1 more source
Advanced Science, EarlyView.Furrow tillage resolves the conventional‐vs.‐no‐tillage trade‐off by simultaneously cutting CO2 efflux to 2.0–3.0 g C m−2 d−1 and unlocking high nutrient availability for the rice rhizosphere. This scalable agronomic solution strengthens soil health, enhances plant physiology, reshapes microbial metabolism, and shifts paddy systems toward a net ...
Arnab Majumdar +10 more
wiley +1 more source
Theory testing (hypothesis testing) in agricultural economics [PDF]
According to Karl Popper, economics and agricultural economics should be deemed scientific if the theories (hypotheses) are subject to strict tests. The testing of agro-economic theories goes back 50 years in the USA, Canada, Europe, and Japan, and these
Meszaros, Sandor
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Advanced Science, EarlyView.Sterol engineering enables precise control of mRNA lipid nanoparticles by tuning membrane organization. Replacing cholesterol with bile acid‐derived sterols redirects protein expression from the liver to the spleen. Notably, CA‐20 LNP enhances antigen‐specific immune responses while exhibiting a favorable safety profile, highlighting sterols as a ...
Sanghyuk Jeon +27 more
wiley +1 more source
Multivariate Contemporaneous-Threshold Autoregressive Models [PDF]
This paper proposes a contemporaneous-threshold multivariate smooth transition autoregressive (C-MSTAR) model in which the regime weights depend on the ex ante probabilities that latent regime-specific variables exceed certain threshold values.
Michael J. Dueker +3 more
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Advanced Science, EarlyView.Liberation of ferulic acid by gut microbial feruloyl esterase mediates cognitive enhancement of germinated quinoa (GQF) on obese mice. Ferulic acid enriched in GQF is released by gut microbes Roseburia hominis and R. intestinalis and subsequently mediates the neuroprotective effects of GQF on obesity‐induced cognitive decline by activating hippocampal ...
Yongli Lan +11 more
wiley +1 more source
Applied Multivariate Research, v.12 no.3 (complete version)
, 2007 The third issue of Applied Multivariate Research edited by Dennis L. JacksonThe article "Cluster analysis and rankings of Canadian universities: Misadventures with rank-based data and implications for the welfare of students" by Kenneth M.
core +1 more source
A Panel of Circulating Exosomal sncRNAs Associated With Lung Cancer Risk up to 10 Years in Advance
Advanced Science, EarlyView.Lung cancer is often diagnosed too late, and current screening overlooks many people at risk. In a long‐term study of smokers, a panel of small non‐coding RNAs carried in blood exosomes signals elevated lung cancer risk up to ten years before diagnosis, pointing toward a blood‐based tool for earlier risk detection.
Zhuokun Feng +12 more
wiley +1 more source