Results 31 to 40 of about 466,566 (229)

Prolonged Corrected QT Interval as an Early Electrocardiographic Marker of Cyclophosphamide‐Induced Cardiotoxicity in Pediatric Hematology and Oncology Patients

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Cyclophosphamide (CY) is associated with potentially fatal cardiotoxicity, yet no electrocardiographic indices have been established for early detection of CY‐induced cardiomyopathy. This study aimed to determine whether corrected QT interval (QTc) prolongation can predict early onset of CY‐related cardiac dysfunction in pediatric ...
Junpei Kawamura, Kentaro Ueno, Takuro Nishikawa, Yoshihiro Takahashi, Koji Nakae, Yasuhiro Okamoto   +5 more
wiley   +1 more source

ECFS-DEA: an ensemble classifier-based feature selection for differential expression analysis on expression profiles

BMC Bioinformatics, 2020
Background Various methods for differential expression analysis have been widely used to identify features which best distinguish between different categories of samples.
Xudong Zhao, Qing Jiao, Hangyu Li, Yiming Wu, Hanxu Wang, Shan Huang, Guohua Wang   +6 more
doaj   +1 more source

Repeated and time-correlated morphological convergence in cave-dwelling harvestmen (Opiliones, Laniatores) from Montane Western North America. [PDF]

PLoS ONE, 2010
BACKGROUND: Many cave-dwelling animal species display similar morphologies (troglomorphism) that have evolved convergent within and among lineages under the similar selective pressures imposed by cave habitats.
Shahan Derkarabetian, David B Steinmann, Marshal Hedin   +2 more
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Epidemiological and virological investigation of a Norovirus outbreak in a resort in Puglia, Italy

BMC Infectious Diseases, 2007
Background This paper describes the third large outbreak of Norovirus (NoV) gastroenteritis reported in the Southern Italy region of Puglia. Methods A matched case control study was conducted, on 19 July 2005, for investigating risk factors, using a ...
Coscia Maria, Santantonio Marilina, Di Bartolo Ilaria, Rizzo Caterina, Monno Rosa, De Vito Danila, Ruggeri Franco, Rizzo Giovanni   +7 more
doaj   +1 more source

Effect of REACT learning strategy on creative thinking and mathematical communication skills

Jurnal Math Educator Nusantara: Wahana Publikasi Karya Tulis Ilmiah di Bidang Pendidikan Matematika, 2022
This study aims to examine the effect of the REACT learning strategy on the creative thinking and mathematical communication skills of MTs/SMP students. The population of this research is class VIII MTs Ma'arif NU 5 academic year 2021/2022, totaling 122
Komarudin Komarudin, Mutia Mutia, Dini Palupi Putri, Ruhban Masykur, Suherman Suherman, Amelia Dwi Astuti   +5 more
doaj   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

EFEKTIVITAS PENDEKATAN REALISTIC MATHEMATICS EDUCATION TERHADAP KECERDASAN LOGIS MATEMATIS DAN KEMAMPUAN BERPIKIR KRITIS MATEMATIK

Aksioma: Jurnal Program Studi Pendidikan Matematika, 2022
Tujuan penelitian ini ingin mengetahui 1)Pengaruh pendekatan realistic mathematics education terhadap kecerdasan logis matematis dan kemampuan berpikir kritis matematik secara multivariat, 2) Pengaruh pendekatan realistic mathematics education terhadap ...
Anggun Pastika Sandi, Asna Lutfa, Amaira Utami   +2 more
doaj   +1 more source

Multiple Comparisons using Composite Likelihood in Clustered Data [PDF]

, 2015
We study the problem of multiple hypothesis testing for multidimensional data when inter-correlations are present. The problem of multiple comparisons is common in many applications.
Azadbakhsh, Mahdis, Gao, Xin, Jankowski, Hanna   +2 more
core  

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source