Results 51 to 60 of about 464,452 (200)

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Gene expression of functionally-related genes coevolves across fungal species: detecting coevolution of gene expression using phylogenetic comparative methods

BMC Genomics, 2020
Background Researchers often measure changes in gene expression across conditions to better understand the shared functional roles and regulatory mechanisms of different genes.
Alexander L. Cope, Brian C. O’Meara, Michael A. Gilchrist   +2 more
doaj   +1 more source

The t-Distribution Approach to the Second-Order Multiresponse Surface Model of Paracetamol Tablets Quality Characteristics

Applied Sciences, 2023
The normal distribution approach is often used in regression analysis at the Response Surface Methodology (RSM) modeling stage. Several studies have shown that the normal distribution approach has drawbacks compared to the more robust t-distribution ...
Pismia Sylvi, Purhadi Purhadi, Kartika Fithriasari, Sutikno Sutikno   +3 more
doaj   +1 more source

Conservative Hypothesis Test of Multivariate Data from an Uncertain Population with Symmetry Analysis in Music Statistics

Symmetry
Music data exhibits numerous distinct symmetric and asymmetric patterns—ranging from symmetric pitch sequences and rhythmic cycles to asymmetric phrase structures and dynamic shifts. These varied and often subjective patterns present notable challenges for data analysis, such as distinguishing meaningful structural features from noise and adapting ...
Anshui Li, Jiajia Wang, Shiqi Yao, Wenxing Zeng   +3 more
openaire   +1 more source

Antibiofilm activity of a chionodracine‐derived peptide by NMR‐based metabolomics of cell‐free supernatant of Acinetobacter baumannii clinical strains

FEBS Open Bio, EarlyView.
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli, Enrico Landi, Francesco Maiurano, Irene Paris, Rosanna Papa, Marco Artini, Laura Selan, Stefano Borocci, Francesco Buonocore, Esther Imperlini   +9 more
wiley   +1 more source

Mathematical problem-solving abilities and reflective thinking abilities: The impact of the influence of eliciting activities models

Al-Jabar, 2020
This study aims to determine the effect of the Model Eliciting Activities (MEAs) learning model to the mathematical problem-solving abilities and the mathematical reflective thinking skills.
Suci Hartati, Ratu Ayu Bilqis, Achi Rinaldi   +2 more
doaj   +1 more source

Estimating Information Processing in a Memory System: The Utility of Meta-analytic Methods for Genetics. [PDF]

PLoS Genetics, 2015
Genetic studies in Drosophila reveal that olfactory memory relies on a brain structure called the mushroom body. The mainstream view is that each of the three lobes of the mushroom body play specialized roles in short-term aversive olfactory memory, but ...
Tugce Yildizoglu, Jan-Marek Weislogel, Farhan Mohammad, Edwin S-Y Chan, Pryseley N Assam, Adam Claridge-Chang   +5 more
doaj   +1 more source

On testing the equality of high dimensional mean vectors with unequal covariance matrices [PDF]

, 2015
In this article, we focus on the problem of testing the equality of several high dimensional mean vectors with unequal covariance matrices. This is one of the most important problem in multivariate statistical analysis and there have been various tests ...
Bai, Zhidong, Hu, Jiang, Wang, Chen, Wang, Wei   +3 more
core  

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

FEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti, Nicolò Gualandi, Gianluca Tell, Giulia Antoniali   +3 more
wiley   +1 more source

The Influence of Book-Tax Differences on Earnings Persistence: A Stakeholder Theory Perspective

Jurnal Akuntansi
This research seeks to explore the influence of AI adoption on ESG performance and further assess the mediation effect of ESG performance in the relation between AI adoption and firm value.
Agustin Palupi
doaj   +1 more source