Results 291 to 300 of about 318,820 (346)

Magnetic resonance imaging features of hypophysitis in patients with cancer treated with immune checkpoint inhibitors

open access: yesJournal of Neuroendocrinology, EarlyView.
This study evaluated pituitary MRI results in cancer patients who experienced immune‐related hypophysitis while receiving immune checkpoint inhibitor treatment. MRI abnormalities were present in 63% of patients at follow‐up and 56% of patients at diagnosis, mostly in patients with multiple hormonal deficiencies.
Anna Angelousi   +10 more
wiley   +1 more source

Metabolic and appetitive regulation of adipocyte mass during treatment of obesity

open access: yesJournal of Internal Medicine, EarlyView.
Abstract Adipose mass is homeostatically maintained within a narrow range despite fluctuations in daily calorie intake and activity levels. Constituting an adipose mass “set point,” this homeostatic regulation includes sensing mechanisms in the form of hormones reflecting caloric intake that serve as mediators of appetitive behaviors and adipose mass ...
Jonathan Q. Purnell, Carel W. Le Roux
wiley   +1 more source

Case reports of oral appliance therapy on three young adults with Down syndrome and OSA

open access: yesJournal of Prosthodontics, EarlyView.
Abstract Patients with Down syndrome (DS) have a high incidence of obstructive sleep apnea (OSA) due to hypotonia, weight, underdeveloped midface, and relative macroglossia. This article presents three cases of young adults with DS, who were diagnosed with mild to severe OSA and unable to tolerate positive airway pressure therapy.
Jingjing Zhang   +3 more
wiley   +1 more source

Herpesvirus Simplex Virus‐1 Exploits Inflammation to Infect Periodontal Stem Cells and Disrupt Lineage Commitment

open access: yesJournal of Periodontal Research, EarlyView.
HSV‐1 infects oral mesenchymal stem cells both in vitro and in vivo to dysregulate their lineage commitment. An inflamed gingival environment increases susceptibility to HSV‐1 infection, which further elevates proinflammatory cytokine levels and exacerbates alveolar bone loss.
Araceli Valverde   +9 more
wiley   +1 more source

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