Results 101 to 110 of about 52,839 (293)
Mesenchymal Stromal Cell‐Based Cell–Drug Conjugates for the Treatment of Acute Liver Failure
Advanced Science, EarlyView.Mesenchymal stromal cell (MSC)‐based cell‐drug conjugates are constructed by anchoring rosiglitazone‐loaded nanoparticles onto the MSC surface. Sustained rosiglitazone release enhances MSC proliferation and paracrine activity while promoting anti‐inflammatory macrophage polarization.
Tenghui Ye +6 more
wiley +1 more source
The congenital muscular dystrophies
Annals of the Child Neurology SocietyBackground Congenital muscular dystrophies (CMDs) are genetically and clinically heterogeneous inherited conditions. Onset is typically within the first year of life.
Haluk Topaloğlu, Bita Poorshiri
doaj +1 more source
Sedation in a Patient with Prader-Willi Syndrome: A Case Report
Haseki Tıp Bülteni, 2014 Prader-Willi syndrome (PWS) is a rare disorder characterized by hypotonia, growth retardation, characteristic face shape, hypogonadism, hyperphagia and related morbid obesity.
Hayrettin Daşkaya +3 more
doaj +1 more source
Prevalence of Prader-Willi Syndrome among Infants with Hypotonia
, 2014 Objective To investigate the prevalence of Prader-Willi syndrome (PWS) in infants with hypotonia between the ages of 0 and 2 ...
Kartal, Nuray +7 more
core +1 more source
Advanced Science, EarlyView.Macrophage RSAD2 dually regulates CMPK2—the rate‐limiting enzyme for mitochondrial DNA synthesis—by suppressing its ubiquitination and promoting its phosphorylation via Csnk2a2 recruitment. This amplifies mtDNA production, which simultaneously activates a cGAS‐STING‐IRF3‐RSAD2 feedforward loop and the NLRP3 inflammasome, driving a self‐sustaining ...
Haomiao Yuan +16 more
wiley +1 more source
Acquired progressive hypotonia in infancy: consider compressive cervical myelopathy.
, 2011 Item does not contain fulltextThis case report presents a rare cause of progressive hypotonia due to a congenital bony defect of the atlas in a 2-month-old girl.
Vollebregt, A +14 more
core +1 more source
Advanced Science, EarlyView.A novel geometry‐resolved membrane platform provides a seamlessly integrated pipeline for studying curvature‐sensing proteins. By linking shotgun proteomics with quantitative imaging, this approach enables both the unbiased discovery and rigorous validation of novel sensors across the entire curvature range—positive, negative, and zero.
Takumi Komikawa +6 more
wiley +1 more source
Coincidence of Nemaline Myopathy and Agenesis of Corpus Callosum in a Newborn Infant: Case Report
Journal of Behçet Uz Children's Hospital, 2019 The diagnosis of the hypotonia at the neonatal period is difficult. In the neonatal period, the differential must include acute illnesses and systemic diseases such as sepsis, congestive heart failure and inborn errors of metabolism. Congenital disorders
Sinem Akbay +7 more
doaj +1 more source
An Injectable, Self‐Expanding Hemostatic Foam for Field‐Compatible Postpartum Hemorrhage Management
Advanced Science, EarlyView.Postpartum hemorrhage is the leading cause of maternal death worldwide, yet many treatments are hard to use outside well‐equipped hospitals. This work introduces an easy‐to‐use device that rapidly delivers a degradable foam into the uterus. The foam stops bleeding through pressure and clotting support, offering a practical option for low‐resource ...
Charlotte Meyer +12 more
wiley +1 more source
Unusual case of Marchiafava-Bignami disease presenting as axial hypotonia
, 2019 © 2019 Inst. Sci. inf., Univ. Defence in Belgrade. All rights reserved. Introduction: Marchiafava-Bignami disease is a rare disorder mostly associated with chronic heavy alcohol consumption that results in progressive demyelination and necrosis of the ...
Jevdjic, Jasna +3 more
core +2 more sources