Results 61 to 70 of about 52,839 (293)

Neonatal peripheral hypotonia: clinical and electromyographic characteristics

open access: yes, 1993
Hypotonia is a common occurrence in pediatrics, especially in the neonatal period. The hypotonic neonate represents a diagnostic challenge for the general pediatrician because hypotonia may be caused by a lesion at any level in the neuraxis: (1) central ...
Parano E, Lovelace RE
core   +1 more source

‘Toning’ up hypotonia assessment: A proposal and critique [PDF]

open access: yes, 2016
Background: Clinical assessment of hypotonia is challenging due to the subjective nature of the initial clinical evaluation. This poses dilemmas for practitioners in gaining accuracy, given that the presentation of hypotonia can be either a non ...
Robin W.E. Joubert   +1 more
core   +1 more source

Whole Gene Deletion of EBF3 Supporting Haploinsufficiency of This Gene as a Mechanism of Neurodevelopmental Disease

open access: yesFrontiers in Genetics, 2017
Mutations in early B cell factor 3 (EBF3) were recently described in patients with a neurodevelopmental disorder (NDD) that includes developmental delay/intellectual disability, ataxia, hypotonia, speech impairment, strabismus, genitourinary ...
Fátima Lopes   +6 more
doaj   +1 more source

Differential diagnosis of hypotonia in infancy [PDF]

open access: yes
Hipotonija ili smanjeni mišićni tonus je klinički simptom koji može upućivati na brojne sistemne bolesti i poremećaje živčanog sustava. S obzirom na velik broj potencijalnih uzroka hipotonije, u postavljanju diferencijalne dijagnoze važno je obradi ...
Matijević, Valentina   +3 more
core   +1 more source

Anorectal Dysfunction in Systemic Sclerosis: Clinical Phenotypes and Functional Patterns

open access: yesArthritis Care &Research, EarlyView.
Objective The aim of this study was to characterize specific physiologic defects in anorectal dysfunction in systemic sclerosis (SSc) using anorectal manometry (ARM), evaluate associations with gastrointestinal (GI) and extraintestinal clinical phenotypes, and explore potential serologic markers for risk stratification.
Timothy Kaniecki   +6 more
wiley   +1 more source

Applicability of the Instrumented Pendulum Test for Assessing Limb Viscoelastic Properties in Neurological and Internal Diseases: A Narrative Review

open access: yesLife
Background: The pendulum test was first introduced by Wartenberg as a clinical tool for neurological examination in patients with hypertonia. It was later instrumented to measure the kinematic parameters of gravity-imposed knee movements in patients with
Maria Stella Valle   +4 more
doaj   +1 more source

A Magneto‐Mechanically Activated Nerve Guidance Conduit Promotes Peripheral Nerve Regeneration via TIMP1‐Mediated Membrane Tension Transfer

open access: yesAdvanced Functional Materials, EarlyView.
This study presents a magneto‐mechanical strategy that incorporates FP@MSCs into an aligned PCL/GelMA nerve guidance conduit. Magnetic stimulation increases membrane tension in FP@MSCs, triggering cytoskeletal remodeling, Schwann cell‐like differentiation, and TIMP1 secretion. TIMP1 activates ITGB1/CD63–FAK signaling in NE‐4C cells, increasing membrane
Xinyu Zhu   +14 more
wiley   +1 more source

Hypotonia and Trophic Changes [PDF]

open access: yesThe Journal of Nervous and Mental Disease, 1918
n ...
openaire   +1 more source

Pelizaeus-Merzbacher Disease and Hypotonia

open access: yes, 1995
Two brothers with Pelizaeus-Merzbacher disease presenting with neonatal hypotonia and hyporeflexia are reported from the Tuft’s University School of Medicine, and Massachusetts General Hospital, Boston, and the EKS Center for Mental Retardation, Waltham,
J Gordon Millichap
core   +1 more source

Microfluidic Nano‐Assembly of Red‐Blood‐Cell (RBC) Lipids and Components for Engineering Extracellular Vesicles

open access: yesAdvanced Healthcare Materials, EarlyView.
Engineered red blood cell‐derived extracellular vesicles (eRBCEVs) are synthesized via controlled microfluidic assembly from native RBC lipids, enabling tunable encapsulation of proteins, nucleic acids, nanoparticles, and viral vectors. The platform demonstrates reproducible nanoscale architecture, preserved membrane composition, and functional cargo ...
Chiranth K. Nagaraj   +23 more
wiley   +1 more source

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