Results 351 to 360 of about 1,114,410 (399)
Some of the next articles are maybe not open access.
Chemical Design and Synthesis of Functionalized Probes for Imaging and Treating Tumor Hypoxia
Chemical Reviews, 2017Hypoxia development in tumor is closely associated with its increased aggressiveness and strong resistance to therapy, leading to the poor prognosis in several cancer types.
Wenbo Bu, Jianlin Shi
exaly +2 more sources
Seminars in Nuclear Medicine, 2015
There is an important and strong, but complex influence of the tumor microenvironment on tumor cells' phenotype, aggressiveness, and treatment sensitivity. One of the most frequent and best-studied aspects of the tumor microenvironment is hypoxia. Low oxygen tension often occurs in tumor cells by several mechanisms, for example, poor angiogenesis and ...
Span, P.N., Span, P.N., Bussink, J.
openaire +4 more sources
There is an important and strong, but complex influence of the tumor microenvironment on tumor cells' phenotype, aggressiveness, and treatment sensitivity. One of the most frequent and best-studied aspects of the tumor microenvironment is hypoxia. Low oxygen tension often occurs in tumor cells by several mechanisms, for example, poor angiogenesis and ...
Span, P.N., Span, P.N., Bussink, J.
openaire +4 more sources
Anesthesiology, 1964
During the past three decades or so a vast amount of research has been done in an effort to discover a procedure, or find some agent, which would increase man's tolerance to hypoxia. For the most part, early studies were concerned with attempts to raise the ceiling of aircraft pilots, that is, enable them to withstand a more severe degree of hypoxia ...
openaire +4 more sources
During the past three decades or so a vast amount of research has been done in an effort to discover a procedure, or find some agent, which would increase man's tolerance to hypoxia. For the most part, early studies were concerned with attempts to raise the ceiling of aircraft pilots, that is, enable them to withstand a more severe degree of hypoxia ...
openaire +4 more sources
Journal of Applied Physiology, 2021
The word “hypoxia” has recently come to the attention of the general public on two occasions, the Nobel Prize in Medicine or Physiology in 2019 and the recent COVID-19 pandemic. In the academic environment, hypoxia is a current topic of research in biology, physiology, and medicine: in October 2020, there were more than 150,000 occurrences of “hypoxia”
openaire +3 more sources
The word “hypoxia” has recently come to the attention of the general public on two occasions, the Nobel Prize in Medicine or Physiology in 2019 and the recent COVID-19 pandemic. In the academic environment, hypoxia is a current topic of research in biology, physiology, and medicine: in October 2020, there were more than 150,000 occurrences of “hypoxia”
openaire +3 more sources
The British Journal of Radiology, 1970
The importance of hypoxia in radiobiology and radiotherapy continues to occupy much space in this journal (Littbrand and Revesz, 1969; Berry, Hall and Cavanagh, 1970). In spite of the excellent review by Boag (1969) we feel the pitfalls, namely: (a) variation in height of medium with its subsequent effect on oxygen diffusion and cell numbers; (b) the ...
J. L. Moore, C. W. Smith
openaire +3 more sources
The importance of hypoxia in radiobiology and radiotherapy continues to occupy much space in this journal (Littbrand and Revesz, 1969; Berry, Hall and Cavanagh, 1970). In spite of the excellent review by Boag (1969) we feel the pitfalls, namely: (a) variation in height of medium with its subsequent effect on oxygen diffusion and cell numbers; (b) the ...
J. L. Moore, C. W. Smith
openaire +3 more sources
Journal of Insect Physiology, 2001
Insects exhibit a remarkable array of adaptations that allow them to handle more or less severe hypoxia associated with numerous aquatic and terrestrial habitats. We consider these habitats and then discuss physiological, behavioral and morphological mechanisms that facilitate insect life under oxygen deprivation.
W. Wyatt Hoback, David Stanley
openaire +2 more sources
Insects exhibit a remarkable array of adaptations that allow them to handle more or less severe hypoxia associated with numerous aquatic and terrestrial habitats. We consider these habitats and then discuss physiological, behavioral and morphological mechanisms that facilitate insect life under oxygen deprivation.
W. Wyatt Hoback, David Stanley
openaire +2 more sources
, 2019 A hypoxic environment can be defined as a region of the body or the whole body that is deprived of oxygen. Hypoxia is a feature of many diseases, such as cardiovascular disease, tissue trauma, stroke, and solid cancers. A loss of oxygen supply usually results in cell death; however, when cells gradually become hypoxic, they may survive and continue to ...
Michael Ladomery, Elizabeth Bowler
openaire +2 more sources
Biogeochemical Controls on Coastal Hypoxia.
Annual Review of Marine Science, 2019Aquatic environments experiencing low-oxygen conditions have been described as hypoxic, suboxic, or anoxic zones; oxygen minimum zones; and, in the popular media, the misnomer "dead zones." This review aims to elucidate important aspects underlying ...
K. Fennel, J. Testa
semanticscholar +1 more source
Annals of the New York Academy of Sciences, 2009
Periods of chronic hypoxia, which can arise from numerous cardiorespiratory disorders, predispose individuals to the development of dementias, particularly Alzheimer's disease (AD). AD is characterized in part by the increased production of amyloid β peptide (Aβ), which forms the extracellular plaques by which the disease can be identified post mortem.
Chris Peers +5 more
openaire +3 more sources
Periods of chronic hypoxia, which can arise from numerous cardiorespiratory disorders, predispose individuals to the development of dementias, particularly Alzheimer's disease (AD). AD is characterized in part by the increased production of amyloid β peptide (Aβ), which forms the extracellular plaques by which the disease can be identified post mortem.
Chris Peers +5 more
openaire +3 more sources
International Urology and Nephrology, 2013
This review mainly focuses on our understanding of spermatogenesis in physiological and pathological hypoxic condition. Real hypoxia is closely related to vascular changes and an increase in testicular temperature. Both induce a reduction in sperm count and can be related to the increase in germ cell apoptosis.
Ljubinka Jankovic Velickovic +1 more
openaire +3 more sources
This review mainly focuses on our understanding of spermatogenesis in physiological and pathological hypoxic condition. Real hypoxia is closely related to vascular changes and an increase in testicular temperature. Both induce a reduction in sperm count and can be related to the increase in germ cell apoptosis.
Ljubinka Jankovic Velickovic +1 more
openaire +3 more sources