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Improving Prognostication in Hypoxic-Ischemic Encephalopathy
Daniel G, Calame, Kristen S, Fisher
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Hypoxic–Ischemic Encephalopathy
Seminars in Neurology, 2017Hypoxic-ischemic encephalopathy (HIE) is one of the most common reasons for hospital neurology consultation. The reasons for neurologic consultations are usually medical management, evaluation and management of myoclonus and seizure activity, and prognosis.
Hans, Friberg, Tobias, Cronberg
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Hypoxic-ischemic encephalopathy
Current Treatment Options in Neurology, 2000Hypoxic-ischemic encephalopathy (HIE) in neonates is often difficult to diagnose in "real time" at the bedside because of the variety of disorders that can cause neonatal seizures and other nonspecific signs of encephalopathy. Standard interventions to support respiratory and cardiovascular disorders associated with HIE are appropriate, but none has ...
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Neonatal Encephalopathy: Beyond Hypoxic-Ischemic Encephalopathy
NeoReviews, 2021Neonatal encephalopathy is a clinical syndrome of neurologic dysfunction that encompasses a broad spectrum of symptoms and severity, from mild irritability and feeding difficulties to coma and seizures. It is vital for providers to understand that the term “neonatal encephalopathy” is simply a description of the neonate’s neurologic status that is ...
Jeffrey B, Russ +2 more
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Hypothermia for Hypoxic-Ischemic Encephalopathy
Clinics in Perinatology, 2008We are entering an era in which hypothermia will be used in combination with other novel neuroprotective interventions. The targeting of multiple sites in the cascade leading to brain injury may prove to be a more effective treatment strategy after hypoxic-ischemic encephalopathy in newborn infants than hypothermia alone.
Rakesh, Sahni, Ulana M, Sanocka
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Hypoxic-Ischemic Encephalopathy
JAMA Pediatrics, 2015Hypoxic-ischemic encephalopathy (HIE) occurs in 1 to 8 per 1000 live births in developed countries. Historically, the clinician has had little to offer neonates with HIE other than systemic supportive care. Recently, the neuroprotective therapy of hypothermia has emerged as the standard of care, and other complementary therapies are rapidly ...
Martha, Douglas-Escobar +1 more
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Management of Hypoxic-ischemic Encephalopathy
The Indian Journal of Pediatrics, 2014Hypoxic-ischemic encephalopathy (HIE), also termed as ‘perinatal asphyxia’ is a medical condition characterized by clinical and laboratory evidence of acute or sub-acute brain injury related to perinatal hypoxic-ischemic event in the neonate. HIE is a major cause of perinatal mortality and cerebral palsy worldwide and affects 2 in 1000 neonates [1].
Siba Prosad, Paul +2 more
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Neonatal encephalopathy and hypoxic–ischemic encephalopathy
2019Acute hypoxic-ischemic encephalopathy around the time of birth remains a major cause of death and life-long disability. The key insight that led to the modern revival of studies of neuroprotection was that, after profound asphyxia, many brain cells show initial recovery from the insult during a short "latent" phase, typically lasting approximately 6h ...
Gunn, A, Thoresen, Marianne
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Hypoxic Ischemic Encephalopathy (Asphyxia)
Pediatric Clinics of North America, 1986This article concerns itself with the effects of HIE on the brain of the full-term infant. Several treatment options are available, with phenobarbital being the drug of choice, but the course remains observation and careful monitoring of the at-risk infant.
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Mimickers of Hypoxic Ischemic Encephalopathy
Clinics in PerinatologyAlthough neonatal encephalopathy is most often caused by hypoxic-ischemic injury, there are many other causes. A careful history and clinical examination allow clinicians to identify neonates with these mimickers, so prompt intervention and support ensue to allow the best developmental outcome.
Gabrielle Russo, Barsh +2 more
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