Results 51 to 60 of about 20,020 (230)
Pathophysiology of Perinatal Asphyxia in Humans and Animal Models
Biomedicines, 2022 Perinatal asphyxia is caused by lack of oxygen delivery (hypoxia) to end organs due to an hypoxemic or ischemic insult occurring in temporal proximity to labor (peripartum) or delivery (intrapartum).
Daniel Mota-Rojas +5 more
doaj +1 more source
Neonatal seizures: Advances in diagnosis and management
Epilepsia Open, EarlyView.Abstract The International League Against Epilepsy (ILAE) created the ILAE Neonatal Task Force that classified neonatal seizures, defined neonatal epilepsy syndromes, and specified treatment guidelines. These frameworks, in addition to improved access to genetic testing and other recent advances, have revolutionized the diagnosis and management of ...
Elissa G. Yozawitz +2 more
wiley +1 more source
Epilepsia Open, EarlyView.Abstract Objective The presence or absence of sleep spindles in patients with infantile epileptic spasms syndrome (IESS) has been proposed as a potential predictor of cognitive outcome; however, the validity of this predictor remains uncertain.
Kento Ohta +6 more
wiley +1 more source
Epilepsia Open, EarlyView.Abstract Objective Lennox–Gastaut syndrome (LGS) is a severe developmental and epileptic encephalopathy (DEE) characterized by multiple seizure types and high resistance to antiseizure medication (ASM), often necessitating nonpharmacologic therapies, including neuromodulation.
Shanna M. Swartwood +11 more
wiley +1 more source
Indian Journal of Radiology and Imaging, 2016 Background: Restricted diffusion within the splenium of the corpus callosum has been described by other authors in various conditions, however, restricted diffusion in the entire corpus callosum or isolated involvement of the splenium, genu, or body has ...
Alok Kale, Priscilla Joshi, A Kelkar
doaj +1 more source
Inflammatory responses in hypoxic ischemic encephalopathy [PDF]
Acta Pharmacologica Sinica, 2013 Inflammation plays a critical role in mediating brain injury induced by neonatal hypoxic ischemic encephalopathy (HIE). The mechanisms underlying inflammatory responses to ischemia may be shared by neonatal and adult brains; however, HIE exhibits a unique inflammation phenotype that results from the immaturity of the neonatal immune system. This review
Liu, Fudong, Mccullough, Louise D
openaire +2 more sources
Epilepsia Open, EarlyView.Abstract Objective Focal cortical dysplasia type 1 (FCD1) is a rare and heterogeneous cause of drug‐resistant epilepsy (DRE) in children. Its clinical characteristics remain poorly understood, and surgical outcomes may be less favorable than in FCD2. We conducted a population‐based study to characterize the clinical presentation and long‐term seizure ...
Vincent Zheng +9 more
wiley +1 more source
Postasphyxial Hypoxic-Ischemic Encephalopathy
Pediatric Neurology Briefs, 1997 Models of association between risk factors and severe adverse outcome within 4 hours of birth were determined in 178 infants with postasphyxiai hypoxic-ischemic encephalopathy (PA-HIE) admitted consecutively between 1985 and 1992 to the regional referral
J Gordon Millichap
doaj +1 more source
Potential biomarkers for hypoxic–ischemic encephalopathy [PDF]
Seminars in Fetal and Neonatal Medicine, 2010 Cerebral hypothermia reduces brain injury and improves behavioral recovery after hypoxia-ischemia (HI) at birth. However, using current enrolment criteria many infants are not helped, and conversely, a significant proportion of control infants survive without disability. In order to further improve treatment we need better biomarkers of injury. A 'true'
L, Bennet, L, Booth, A J, Gunn
openaire +2 more sources
International Journal of Gynecology &Obstetrics, Volume 169, Issue 1, Page 408-420, April 2025.Abstract Objective Birth asphyxia is one of the leading causes of death for neonates worldwide. Lack of an objective cost effective test to predict poor newborn outcomes at birth affects the ability to respond appropriately. This study determined predictive values of umbilical cord arterial lactate in relation to adverse neonatal outcomes. Methods This
Elizabeth Ayebare +7 more
wiley +1 more source