Results 91 to 100 of about 12,758 (223)

Pannexin 1: a novel regulator of acute hypoxic pulmonary vasoconstriction. [PDF]

Cardiovasc Res, 2022
Grimmer B, Krauszman A, Hu X, Kabir G, Connelly KA, Li M, Grune J, Madry C, Isakson BE, Kuebler WM.   +9 more
europepmc   +1 more source

Role of reactive oxygen species in mediating peripheral hypoxic vasodilation and sympathoexcitation at high altitude

The Journal of Physiology, EarlyView.
Abstract figure legend High‐altitude acclimatisation increases muscle sympathetic nerve activity (MSNA) via activation of the arterial chemoreflex, pulmonary arterial baroreceptors and resetting of the sympathetic vascular baroreflex. However attempting to silence these mechanisms only partially normalises MSNA, implicating other contributory ...
Liam D. Corr, Andrew J. M. Douglas, Elliott J. Jenkins, Lauren E. Maier, Jodie L. Koep, Travis D. Gibbons, Adam Field, James D. Anholm, Katharine Foster, Zoe H. Adams, Lydia L. Simpson, Jonathan P. Moore, Tinna Traustadottir, Christoph Siebenmann, Joshua C. Tremblay, Mike Stembridge   +15 more
wiley   +1 more source

A song of iron and oxygen: Hypoxic pulmonary vasoconstriction and gas exchange in chronic obstructive pulmonary disease. [PDF]

Exp Physiol, 2023
Hartmann JP, Bailey DM, Berg RMG.
europepmc   +1 more source

Severe intraoperative hypercarbia undetected by continuous end-tidal CO2 monitoring in a chronic smoker undergoing one-lung ventilation

The Indian Anaesthetists' Forum, 2016
One-lung ventilation is known to alter the physiology and result in a discrepancy between end-tidal CO2 (ETCO2) and arterial blood CO2partial pressure despite protective mechanisms like hypoxic pulmonary vasoconstriction.
Shagun Bhatia Shah, Binod Kumar Naithani, Vani Bhageria, Ajay Kumar Bhargava   +3 more
doaj   +1 more source

Differential Effects of Phosphodiesterase-5 Inhibitors on Hypoxic Pulmonary Vasoconstriction and Pulmonary Artery Cytokine Expression [PDF]

, 2005
Ben M. Tsai, Mark W. Turrentine, Brett C. Sheridan, Meijing Wang, Andrew C. Fiore, John W. Brown, Daniel R. Meldrum   +6 more
openalex   +1 more source

ROC‐325 Attenuates Hypoxia‐Induced Pulmonary Hypertension Through Dual Inhibition of Autophagy and Hypoxia‐Inducible Factor 2α Signaling

MedComm – Future Medicine, Volume 5, Issue 1, March 2026.
In hypoxia‐induced pulmonary hypertension, endothelial HIF‐2α accumulation and autophagic activation drive vascular remodeling. We demonstrate that the novel lysosomal inhibitor ROC‐325 simultaneously attenuates this pathogenic autophagy and promotes HIF‐2α degradation.
Changlei Bao, Shuxin Liang, Dingyuan Liu, Xingting Wang, Dan Bai, Chuangjia Huang, Hanliang Sun, Zi Yang, Bitao Wu, Zixuan Chen, Jieyi Feng, Zinan Luo, Jintao Long, Jinsheng Zhu, June Bai, Li Zhang, Aiai Chu, Caojin Zhang, Haiyang Tang   +18 more
wiley   +1 more source

Activation of neutral sphingomyelinase is involved in acute hypoxic pulmonary vasoconstriction [PDF]

, 2008
Ángel Cogolludo, Laura Moreno, Giovanna Frazziano, Javier Moral‐Sanz, C. Menéndez, Javier Castañeda, C. González, Eduardo Villamor, Francisco Pérez‐Vizcaíno   +8 more
openalex   +1 more source

The Impact of High‐Intensity Exercise in Normobaric Hypoxia on Right Ventricular Function in Trained and Untrained Men—An Echocardiographic Study

Comprehensive Physiology, Volume 16, Issue 1, February 2026.
A single bout of high‐intensity exercise to volitional exhaustion under acute normobaric hypoxia (~3000 m a.s.l.; FiO2 = 14.4%) does not induce greater alterations in right ventricular systolic function compared to normoxia in either trained or untrained healthy men.
Gajda Robert, Czuba Miłosz, Płoszczyca Kamila, Kowalik Ewa, Niemaszyk Adam, Starczewski Michał, Grzebisz‐Zatońska Natalia, Kaczmarczyk Katarzyna, Langfort Józef   +8 more
wiley   +1 more source

Intraoperative hypoxemia during one-lung ventilation: Is it still an anesthesiologists' nightmare? (hypoxemia during one-lung ventilation) [PDF]

Serbian Journal of Anesthesia and Intensive Therapy, 2019
Lung isolation is used for various surgical and non-surgi-cal reasons. This type of ventilation carries the risk for va-rious degrees of ventilation/perfusion mismatch associa-ted with lateral decubitus position, one-lung ventilation (OLV) and opened ...
Janković Radmilo J., Stojanović Milena, Vuković Anita, Dinić Vesna, Cvetanović Vladan, Marković Danica   +5 more
doaj  

Effect of moderate altitude and nocturnal oxygen therapy on cerebrovascular function in patients with COPD: A randomized, crossover trial at 2048 m

Experimental Physiology, Volume 111, Issue 2, Page 527-538, 1 February 2026.
Abstract We investigated whether nocturnal oxygen therapy improves next‐day cerebrovascular function in lowlanders with chronic obstructive pulmonary disease (COPD) staying at moderate altitude. This randomized, placebo‐controlled single‐blind crossover trial was performed in moderate‐to‐severe COPD patients [forced expiratory volume in 1 s (FEV1 ...
Dominic Gilliand, Tsogyal D. Latshang, Sayaka S. Aeschbacher, Fabienne Huber, Deborah Flueck, Mona Lichtblau, Stefanie Ulrich, Elisabeth D. Hasler, Philipp M. Scheiwiller, Julian Müller, Silvia Ulrich, Konrad E. Bloch, Michael Furian   +12 more
wiley   +1 more source