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Neurology, 1997 To determine the frequency and significance of the EEG features of hypsarrhythmia, we analyzed the pre-ACTH records of 53 consecutive patients with infantile spasms for the severity of the following abnormalities: disorganization of background, slowing, high amplitude, spike activity, and for the presence or absence of each of the following patterns ...
Mohamad A. Mikati, W. C. Sue, Uri Kramer
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Scoring Systems for the Evaluation of Hypsarrhythmia
Journal of Clinical Neurophysiology, 2022Summary: Hypsarrhythmia is a well-recognized EEG pattern and it has been long known as a feature of one of the more severe forms of epilepsy early in life with adverse consequences if not recognized and treated promptly. Yet, it has been difficult to objectively quantify its varied manifestations and link them to the clinical severity of ...
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Hypsarrhythmia: Variations on the Theme
Epilepsia, 1984Summary: Prolonged monitoring studies of patients with infantile spasms have shown that hypsarrhythmia is a highly variable and dynamic electroencephalographic pattern. Variations of the prototypic pattern (modified hypsarrhythmia) include hypsarrhythmia with increased in‐terhemispheric synchronization, asymmetrical hypsarrhythmia, hypsarrhythmia with
Peter Kellaway +2 more
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Quantitative Characteristics of Hypsarrhythmia in Infantile Spasms
2018 40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), 2018Infantile spasms is a type of epilepsy characterized by clinical seizures termed "spasms" and often an electroencephalographic (EEG) pattern known as hypsarrhythmia. Multiple studies have shown that the interrater reliability for human visual recognition of hypsarrhythmia is poor.
Daniel W. Shrey +3 more
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Hypsarrhythmia and infantile autism: A clinical report
Journal of Autism and Childhood Schizophrenia, 1971The case histories of five children, four boys and one girl (1 to 9 years of age), who developed autistic behavior after the onset of infantile spasms, are presented in detail. The patients' initial EEGs disclosed hypsarrhythmia. First onsets of seizures occurred during the second 6 months of life in four and on the third day of life in the youngest ...
Lawrence T. Taft, Herbert J. Cohen
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Successful zonisamide treatment for infants with hypsarrhythmia
Pediatric Neurology, 2000We determined that zonisamide was effective in three epileptic infants with hypsarrhythmia. Two patients had the electroencephalographic pattern of hypsarrhythmia associated with developmental delay but lacked the characteristic tonic spasms. A third patient exhibited the typical triad of infantile spasms but had a poor general condition requiring ...
Yoshihisa Nejihashi +3 more
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Asymmetric Hypsarrhythmia and Infantile Spasms in West Syndrome
Journal of Child Neurology, 1994The video encephalograms (EEGS) of 77 consecutive infantile spasms patients were evaluated for the presence of focal or asymmetric hypsarrhythmia and infantile spasms, to determine whether these findings were useful in predicting the presence of focal structural brain disease and were of any additional diagnostic or prognostic significance.
Jane F. Donat, Warren D. Lo
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Epileptic spasms in clusters without hypsarrhythmia in infancy
Epileptic Disorders, 2003Spasms are defined as epileptic seizures characterized by brief axial contraction, in flexion, extension or mixed, symmetric or asymmetric, lasting from a fraction of a second to 1‐2s, and are associated with a slow‐wave transient or sharp and slow‐wave complex, followed or not by voltage attenuation. Epileptic spasms usually appear in clusters and are
CARABALLO R. H. +6 more
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Epileptic spasms in clusters without hypsarrhythmia
Journal of Pediatric Epilepsy, 2015Here we present an update of the electroclinical features and evolution of patients with epileptic spasms (ES) in clusters without hypsarrhythmia, with or without focal or generalized paroxysmal discharges on the interictal electroencephalography (EEG).
Fortini Sebastian +3 more
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Magnetoencephalographic analysis of hypsarrhythmia in West Syndrome
Journal of Epilepsy, 1997Abstract Magnetoencephalography (MEG) was performed in 7 patients with West syndrome (WS). In patients who had localized lesions such as tuberous sclerosis and porencephaly in the cerebral cortex, MEG showed clusters of sources of epileptiform discharges (EDs) of hypsarrhythmia at these lesions.
Taketsugu Minami +6 more
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