Results 141 to 150 of about 120,832 (296)

Pelvic Exenteration for Cervical Cancer: Oncological, Morbidity and Quality of Life Outcomes

Journal of Surgical Oncology, EarlyView.
ABSTRACT Background and Objectives One third of patients who undergo definitive chemoradiotherapy for locally advanced cervical cancer develop disease recurrence. Salvage surgery in the form of pelvic exenteration (PE) may offer improved survival and possibly cure in carefully selected patients, however robust data is scarce.
Alexandra M. Peacock, Kilian G.M. Brown, Peter J. M. Lee, Kirk K. S. Austin, Christopher M. Byrne, Daniel Steffens, Michael J. Solomon   +6 more
wiley   +1 more source

The Choice Between Definitive Radiotherapy and Surgery for Cervical Cancer With Different Histology in Current Clinical Practice

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT For cervical cancer, the choice between definitive radiotherapy (RT) and surgery has long been a topic of debate. Clinical factors, including histology and tumor burden, have been examined in prior studies. Given recent advances in RT and the incorporation of concurrent chemotherapy, our study seeks to assess the optimal treatment modality for
Yu‐Lun Wu, Chen‐Wei Ho, Wen‐Shiung Liou, Chun‐Hao Yin, Jin‐Shuen Chen, Yao‐Shen Chen, Yu‐Wei Lin, Ju‐Chun Chien   +7 more
wiley   +1 more source

Evolving Sacrocolpopexy Technique Trends

Neurourology and Urodynamics, EarlyView.
ABSTRACT Introduction Sacrocolpopexy (SCP) is widely considered the gold standard procedure for repairing apical and multi‐compartment prolapse. Despite its long‐standing and widespread use, significant technical variations persist, yet these differences have not been well‐characterized or linked to surgical outcomes.
Christina Sze, Carolina Martinez Fernandez, Gabriel Andino, Maali LaFrance Frater, Stephanie Sansone, Sonia Bhandari Randhawa, Gary E. Lemack, Ramy Goueli, Maude Carmel   +8 more
wiley   +1 more source

Surgical Treatment of Pelvic Organ Prolapse and Overactive Bladder: A Systematic Review and Meta‐Analysis

Neurourology and Urodynamics, EarlyView.
ABSTRACT Background Pelvic organ prolapse (POP) frequently coexists with overactive bladder (OAB) symptoms, yet the impact of surgical correction on OAB outcomes remains incompletely characterized across different surgical approaches. Objectives To quantify OAB symptom resolution rates following POP surgery, compare outcomes across surgical techniques,
Lorenzo Vacca, Daniela Caramazza, Michele Pierro, Aniello Foresta, Andrea Lombisani, Anna Fagotti, Alfredo Ercoli, Giuseppe Campagna   +7 more
wiley   +1 more source

Population Pharmacokinetics and Transfer of Gabapentin When Used as a Pain Adjunct for Cesarean Deliveries

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 551-560, March 2025.
ABSTRACT Enhanced Recovery After Surgery (ERAS) protocols for cesarean deliveries (CDs) utilize multimodal pain management strategies that often include gabapentin. While gabapentin is excreted in breast milk, its pharmacokinetics in immediately postpartum lactating women are not known. This observational pharmacokinetic study (NCT05099484) enrolled 21
Rebecca Silvola, Aislinn O'Kane, Michael Heathman, Hannah Marotta, Hayley Trussel, Bobbie Ray, Shelley Dowden, Andrea R. Masters, David M. Haas, Sara K. Quinney   +9 more
wiley   +1 more source

Hormone Replacement Therapy Uptake and Discontinuation Trends From 1996‐2023: An Observational Study of the Welsh Population

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective To analyse prescribing trends for oral and transdermal hormone replacement therapy (HRT) in Wales from 1996 to 2023, including predictors of discontinuation within one year of initiation. Design Observational study using the Secure Anonymised Information Linkage (SAIL) databank.
Robin Andrews, Arron Lacey, Kate Bache, Emma J. Kidd   +3 more
wiley   +1 more source

The Role of Vaginal Oestrogen Therapy in Postmenopausal Women With Pelvic Organ Prolapse: Does It Have Any Impact on Perioperative Outcomes? A Systematic Review of Randomised Controlled Trials

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Background Pelvic organ prolapse (POP) affects up to 50% of postmenopausal women, negatively impacting sexual function and quality of life. While surgery remains the primary treatment, increasing attention has been given to perioperative vaginal oestrogen therapy and its potential impact on surgical outcomes.
Gilda Sicilia, Salvatore Giovanni Vitale, Maurizio Nicola D'Alterio, Stefania Saponara, Francesco Scicchitano, Anna Maria Fulghesu, Rossella E. Nappi, Stefano Angioni   +7 more
wiley   +1 more source

vNOTES hysterectomy with a homemade glove port: Initial experience in Singapore

Vaginal natural orifice transluminal endoscopic surgery (vNOTES) is an established surgical method of performing hysterectomy via the vaginal route and is one of the latest editions to the realm of minimally invasive surgery.
Nadarajah Ravichandran, Wei Jie Brandon Khaw, Wei Heng, Yu Chung Harold Chan, Wan Yu Yvonne Wong, Yafang Tang, Joella Xiaohong Ang   +6 more
core   +1 more source

DNA‐Methylation for Risk‐Stratification of Women Without a Fully Visible Transformation Zone at Colposcopy: A Cross‐Sectional Study

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective To evaluate the performance of DNA methylation markers for the detection of cervical precancer among screening‐positive older women without a fully visible transformation zone at colposcopy (TZ3). Design Cross‐sectional study. Setting Colposcopy clinics, Central Denmark Region, 2019–2021.
Karen Omann Binderup, Joachim Boers, Line Winther Gustafson, Berit Andersen, Lone Kjeld Petersen, Pinar Bor, Joost Gribnau, Wim G. V. Quint, Henk Van Den Munckhof, Mette Tranberg, Anne Hammer   +10 more
wiley   +1 more source

Chronic pain after hysterectomy

, 2008
BACKGROUND: Chronic pain is a well-known adverse effect of surgery, but the risk of chronic pain after gynaecological surgery is less established. METHOD: This review summarizes studies on chronic pain following hysterectomy.
Nikolajsen, L., Brandsborg, B., Jensen, T.S., Kehlet, H.   +3 more
core   +1 more source