Results 41 to 50 of about 182,060 (336)

Depression Symptom Trajectories in Mothers With the FMR1 Premutation Vary by CGG Repeat Length: A Longitudinal Study of 73 Women Spanning 20–75 Years of Age

open access: yesAmerican Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT Women with the FMR1 premutation (FXpm) are at heightened genetic vulnerability for depression, with risk compounded by the stressors of parenting a disabled child. Although risk factors persist as FXpm women age, depression in FXpm mothers during midlife and old age is poorly characterized. This study used an accelerated longitudinal design to
Jessica Klusek   +8 more
wiley   +1 more source

Factors for a Successful Laparoscopic Hysterectomy in Very Large Uteri

open access: yesCase Reports in Medicine, 2017
Minimally invasive hysterectomy is a standard procedure. Different approaches, as laparoscopically assisted vaginal hysterectomy, vaginal hysterectomy, and subtotal and total laparoscopic hysterectomy, have been described and evaluated by various ...
Harald Krentel, Rudy Leon De Wilde
doaj   +1 more source

Drug–drug interaction profile of ritlecitinib as perpetrator and victim through cytochrome P450

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims To assess the effect of a potent cytochrome P450 (CYP) 3A inhibitor and CYP inducer on the pharmacokinetics of ritlecitinib, a JAK3/TEC family kinase inhibitor, and assess the effect of ritlecitinib on the pharmacokinetics of CYP substrates (midazolam, efavirenz, tolbutamide, caffeine and oral contraceptives [ethinyl oestradiol and levonorgestrel])
Vivek S. Purohit   +6 more
wiley   +1 more source

Trends in Hysterectomy Incidence Rates During 2000–2015 in Denmark: Shifting from Abdominal to Minimally Invasive Surgical Procedures

open access: yesClinical Epidemiology, 2021
Kathrine Dyhr Lycke,1,2 Johnny Kahlert,3 Rikke Damgaard,1,2 Ole Mogensen,2,4 Anne Hammer1,2,4 1Department of Obstetrics and Gynecology, NIDO | Denmark, Gødstrup Hospital, Herning, Denmark; 2Department of Clinical Medicine, Aarhus University ...
Lycke KD   +4 more
doaj  

Efficacy and safety of using mesh or grafts in surgery for anterior and/or posterior vaginal wall prolapse: systematic review and meta-analysis. [PDF]

open access: yes, 2008
Background The efficacy and safety of mesh/graft in surgery for anterior or posterior pelvic organ prolapse is uncertain. Objectives To systematically review the efficacy and safety of mesh/graft for anterior or posterior vaginal wall prolapse surgery.
Bain, Christine   +6 more
core   +2 more sources

A 5-year review of hysterectomy at the Delta State University Teaching Hospital, Oghara, south-south Nigeria

open access: yesIbom Medical Journal, 2023
Context: Hysterectomy is a major surgical procedure that is performed worldwide for several indications ranging from benign to malignant conditions. It may be life-saving especially in certain obstetric situations. Objective: The aim was to determine
Ukah CE   +3 more
doaj   +1 more source

p16INK4a and HPV E4 immunohistochemistry for the prediction of regression of cervical intraepithelial neoplasia grade 2—A historical cohort study

open access: yesInternational Journal of Cancer, EarlyView.
What's New? Immunohistochemical biomarkers are increasingly used for the grading of cervical intraepithelial neoplasia (CIN); however, their clinical utility in the prediction of CIN2 regression is largely unexplored. Here, the authors analyzed the risk of CIN2 regression in relation to p16INK4a and HPVE4 immunohistochemistry in a large cohort of women
Rikke Damgaard   +10 more
wiley   +1 more source

Randomised comparison of uterine artery embolisation (UAE) with surgical treatment in patients with symptomatic uterine fibroids (REST trial): 5-year results [PDF]

open access: yes, 2011
Objective: To compare the long-term results of uterine artery embolisation (UAE) with surgery for women with symptomatic uterine fibroids. Design Pragmatic, open, multicentre, randomised trial. Setting Twenty-seven participating UK secondary care centres.
Dutton   +15 more
core   +1 more source

Associations of sarcopenia, sarcopenia components and sarcopenic obesity with cancer incidence: A prospective cohort study of 414,094 participants in UK Biobank

open access: yesInternational Journal of Cancer, EarlyView.
What's New? Sarcopenia is highly prevalent and associated with adverse outcomes in cancer survivors. However, evidence regarding the role of sarcopenia in the general population as a potential risk factor for cancer development is scarce. This prospective cohort study investigated the association of sarcopenia with the incidence of 19 cancers in a ...
Panagiotis Filis   +8 more
wiley   +1 more source

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