Results 31 to 40 of about 16,783 (261)

Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky, Cara Joyce, H. Jeremy Bockholt, Paul A. Rudnick, William H. Adams, Fiona McAllister, Justin W. Smock, Michael A. Newton, Jane S. Paulsen   +8 more
wiley   +1 more source

Exploring Patients’ Profiles Associated With the Resolution of Acute Calcium Pyrophosphate Arthritis Treated With Colchicine and Prednisone: Post Hoc Analysis of a Randomized Controlled Trial

Arthritis Care &Research, EarlyView.
Objective The objective was to identify factors determining acute arthritis resolution and safety with colchicine and prednisone in acute calcium pyrophosphate (CPP) crystal arthritis. Methods We conducted a post hoc analysis of the COLCHICORT trial, which compared colchicine and prednisone for the treatment of acute CPP crystal arthritis, using a ...
Tristan Pascart, Laurène Norberciak, Pascal Richette, Pierre Robinet, Aurore Pacaud, Gauthier Marchasson, Thibault Rabin, Hélène Luraschi, Pierre Maciejasz, Anne‐France Georgel, Augustin Latourte, Hang‐Korng Ea, Sébastien Ottaviani, Charlotte Jauffret, Vincent Ducoulombier   +14 more
wiley   +1 more source

Esiste ancora l’isteria? Prospettive diagnostiche in Gestalt Therapy

Phenomena Journal, 2019
The article analyzes some motivations of the disappearance of hysteria, retracing the novelties of the Freudian theory of hysteria (and the rereading of feminist theories), comes to a phenomenological-relational reinterpretation of hysterical ...
Rosaria Lisi
doaj   +1 more source

Engineering Free Volume within Frontal Ring‐Opening Metathesis Polymerization via Pendant Plasticization

Advanced Materials, EarlyView.
Norbornene‐based copolymers with tunable n‐alkyl pendant length provide control over matrix free volume, enabling elastomeric materials via frontal ring‐opening metathesis polymerization (FROMP). ABSTRACT Frontal ring‐opening metathesis polymerization (FROMP) enables rapid, energy‐efficient access to high‐performance thermosets and thermoplastics, but ...
Kevin A. Stewart, Francesca J. Lombardi, Sky D. Cao, Claire M. Massouh, Jacob J. Lessard   +4 more
wiley   +1 more source

Neuronal Cholesterol Deficiency Mediated by Astrocytic SREBP2 Downregulation Leads to Postoperative Cognitive Dysfunction Through Impairment of Hippocampal Synaptic Plasticity and Excitatory Synaptic Transmission

Advanced Science, EarlyView.
The results showed that the reduction of plasma 24‐hydroxycholesterol (24‐OHC) was related to the cognitive decline in elderly surgical patients. Neuroinflammation induced by anesthesia and surgery significantly downregulated SREBP2 in hippocampal reactive astrocytes, resulting in reduced cholesterol synthesis.
He Huang, Chenrui Zhou, Chen Chen, Huimei Tang, Wei Dong, Jie Wan, Weiye Kang, Ao Sun, Yiqi Liu, Chunhui Jin, Xiaobin Lyu, Yankun Zhu, Chenghua Zhou, Yuqing Wu   +13 more
wiley   +1 more source

Battered and sexually abused children: connections with the Freudian theory of seduction and its rejection

Ricerca Psicoanalitica, 2020
It refers to what Masson says about Freud's abandonment of the theory of seduction. Then two different versions of Freud's dream about "closing one's eyes" are analyzed, as well as recent criticism of Freud by Miller, Krüll and Bowlby, and past criticism
Pierangela Piccinini
doaj   +1 more source

Hysteria: history of a conceptual and clinical pathomorphosis

European Psychiatry, 2022
Introduction Transhistorical psychiatry defends that a psychic alteration can be interpreted as a cultural, historical and personal construction, subject to incessant variations.
A. Sanz Giancola, C. Alvarez Garcia
doaj   +1 more source

Electro‐Chemo‐Mechanical Coupling in Composite Cathodes of Sulfide‐Based All‐Solid‐State Batteries: Pathways, Degradation, and Design Rules

Advanced Science, EarlyView.
This review provides an integrated framework for achieving superior electrochemical performance in sulfide‐based all‐solid‐state batteries. It first delineates mechano‐electrochemical failure modes of cathode active materials and solid electrolytes, then outlines engineering principles for particle morphology, electronic and ionic conduction, and ...
Gawon Song, Seonghyun Lee, Minseon Lee, Junsung Park, Kyu Tae Lee   +4 more
wiley   +1 more source

Hitler's hysterical blindness: fact or fiction? A cegueira histérica de Hitler: fato ou ficção?

Arquivos de Neuro-Psiquiatria, 2010
This article deals with a little known episode that occurred near the end of the Great War in a military reserve hospital located in the small town of Pasewalk, part of the distant region of Pomerania in northern Poland.
Péricles Maranhão-Filho, Carlos Eduardo da Rocha e Silva   +1 more
doaj   +1 more source

Combination of Ethoxybenzyl‐Diethylenetriamine Pentaacetic Acid‐Enhanced Magnetic Resonance Imaging and a Serum Biomarker Is Useful in the Diagnosis of Hepatic Sinusoidal Disorder After Chemotherapy Treatment

Annals of Gastroenterological Surgery, EarlyView.
ROC analyses of APRI score, EOB‐MRI, and a combination of EOB‐MRI and APRI score for blue liver. ABSTRACT Aim Sinusoidal obstruction syndrome (SOS), also known as “blue liver (BL),” is a common hepatic injury following oxaliplatin‐based chemotherapy in patients with colorectal liver metastases (CRLM).
Tomonari Shimagaki, Keishi Sugimachi, Takahiro Tomino, Takeshi Kurihara, Emi Onishi, Yutaro Shimomura, Kenji Shinozaki, Masaru Morita   +7 more
wiley   +1 more source