Evaluating the Effects of Nusinersen Treatment in Adults With Spinal Muscular Atrophy Using Axonal Excitability and MscanFit MUNE. [PDF]
ABSTRACT Introduction/Aims The biological changes in motor neurons and motor axons that correlate with the clinical benefits of nusinersen, an antisense oligonucleotide, in spinal muscular atrophy (SMA) remain poorly understood. This study aimed to investigate changes in axonal excitability and motor unit number estimation (MUNE) parameters following a
Alaamel A +4 more
europepmc +2 more sources
The Relationship Between the Index of Cardio-Electrophysiological Balance and the Non-Dipper Hypertensive Pattern in Patients With Newly Diagnosed Hypertension. [PDF]
ABSTRACT The connection between different electrocardiography (ECG) parameters and circadian blood pressure (BP) variations in patients with hypertension (HT) has been investigated. The index of cardio‐electrophysiological balance (iCEB), determined as the quotient of the QT interval and the QRS duration, offers an assessment of the comprehensive ...
Karakurt ST +3 more
europepmc +2 more sources
Electrical stimulation of stem cell-derived human neural networks for evaluating anti-seizure medications. [PDF]
Abstract Objective Current preclinical epilepsy drug screening relies on animal models that poorly reflect human neurophysiology, leading to high failure rates in clinical translation. We aimed to establish a human in vitro model using human‐induced pluripotent stem cell (hiPSC)–derived cortical neurons cultured on multielectrode arrays (MEAs), capable
Nicholls J +14 more
europepmc +2 more sources
Time-Dependent Effects of Low-Intensity Pulsed Ultrasound on Apoptosis and Autophagy in Malignant Melanoma Stem Cells. [PDF]
ABSTRACT Cancer stem cells (CSCs) in malignant melanoma contribute to therapeutic resistance and tumour recurrence. While low‐intensity pulsed ultrasound (LIPUS) has been proposed as a non‐invasive strategy to induce cell death, its effects on CSC‐specific apoptotic and autophagic responses remain unclear. This study aimed to explore the time‐dependent
Dikici O +5 more
europepmc +2 more sources
Time-Frequency Warped Waveforms [PDF]
The forthcoming communication systems are advancing towards improved flexibility in various aspects. Improved flexibility is crucial to cater diverse service requirements.
Arslan, Huseyin +2 more
core +2 more sources
Erkânname Geleneğinde Siyer ve Tarih Referansları: Arnavutluk Arşivinde Bir Yazma Örneği
Erkânnameler, Bektaşîliğin inanç ve ibadet sistemini ortaya koyan metinlerdir. Hacı Bektaş Veli’nin ölümünden sonra kaleme alınan ve onun öğretilerini yansıtan manzum ve nesirlerden oluşan yapıtlardır.
Mehmet Çakırtaş
doaj +1 more source
Transcutaneous Vagus Nerve Stimulation Effects on Flavor-Evoked Electroencephalogram and Eye-Blink Rate. [PDF]
ABSTRACT Introduction Chemosensory food signals are carried by the vagus nerve (VN) from the gut to the brain and these signals contribute to communicating fullness and caloric value of the consumed food in regulatory and reward‐related contexts. Here, we aimed to explore whether neural responses to flavor can be modulated through noninvasive VN ...
Albayrak S +7 more
europepmc +2 more sources
Multimodal person recognition for human-vehicle interaction [PDF]
Next-generation vehicles will undoubtedly feature biometric person recognition as part of an effort to improve the driving experience. Today's technology prevents such systems from operating satisfactorily under adverse conditions.
Abut, Huseyin +9 more
core +1 more source
Ahmediler’de Şii Söylem: “Muharrem Ayı ve Hz. Hüseyin’in Yüce Konumu” İsimli Cuma Hutbesi Örneği
Hint coğrafyasında, İslâm çeşitli değişim ve dönüşümler geçirerek tarih sahnesindeki varlığını devam ettirmiş; farklı din söylemlerini sentezleyen pek çok yeni dini yapılanma ortaya çıkmıştır.
Halide Rumeysa Küçüköner
doaj +1 more source
Hil’at-Nâme-i Hasan-Hüseyin: Peygamber Torunlarının Katline Dair Bir Kehanet Anlatısı
Hz. Muhammed’in torunları Hz. Hasan ve Hüseyin’in değişik zamanlarda ve değişik biçimlerde öldürülmelerinin temelinde siyasi erk mücadelesi yatmaktadır. Özellikle Hz.
Özkan DAŞDEMİR
doaj

