Results 1 to 10 of about 10,371 (187)

The Histone Deacetylase Inhibitor I13 Induces Differentiation of M2, M3 and M5 Subtypes of Acute Myeloid Leukemia Cells and Leukemic Stem-Like Cells

Frontiers in Oncology, 2022
Acute myeloid leukemia (AML) is a heterogeneous hematologic malignancy characterized by reduced differentiation of myeloid cells and uncontrolled cell proliferation.
Xiangyu Ma, Mengjie Zhao, Zhuoxun Wu, Jingfang Yao, Lei Zhang, Jinhong Wang, Zhenbo Hu, Liuya Wei, Zhe-Sheng Chen   +8 more
semanticscholar   +3 more sources

I13 overrides resistance mediated by the T315I mutation in chronic myeloid leukemia by direct BCR-ABL inhibition

Frontiers in Pharmacology, 2023
Chronic myeloid leukemia (CML) is a myeloproliferative neoplasm caused by a BCR-ABL fusion gene. Imatinib has significantly improved the treatment of CML as a first-generation tyrosine kinase inhibitor (TKIs). The T315I mutant form of BCR-ABL is the most
Congying Gao, Lei Zhang, Yun Xu, Xiangyu Ma, Peilei Chen, Zhe-Sheng Chen, Liuya Wei   +6 more
semanticscholar   +3 more sources

Optical autocollimator for vibration measurements at Diamond I13 beamline

Journal of Physics: Conference Series, 2022
Abstract I13 is a 250 m long hard X-ray beamline for imaging and coherence experiments at the Diamond Light Source [1]. The beamline comprises two independent experimental branches: one for imaging in direct space using X-ray microscopy and one for imaging in reciprocal space using coherent imaging techniques. The mechanical stability is
Kachkanov, V., Ziesche, R., Wagner, U.H., Batey, D., Li, P., Rau, C.   +5 more
openaire   +3 more sources

Complete genome sequence of <i>Azospira</i> sp. strain I13 harboring two distinct nitrous oxide reductase (<i>nosZ</i>) genes. [PDF]

Microbiol Resour Announc
We report on the complete genome sequence of Azospira sp. strain I13, a class of Betaproteobacteria. We identified two distinct nitrous oxide (N2O) reductase (nosZ) genes in the retrieved genome.
Ok Y, Yasuda S, Ogawa T, Hosaka A, Yohda M, Terada A.   +5 more
europepmc   +2 more sources

I13 Neutrophils and innate immunity in the pathogenesis of SLE [PDF]

Invited talks, 2020
Background Innate immunity cells, cytokines and inflammatory pathways have been recognised as inducers and amplifiers of autoimmune responses and tissue injury in SLE. Methods Published experimental data during the last five years on the contribution of innate immunity, particularly neutrophils and type I interferon, are summarized and their ...
G. Bertsias
openaire   +2 more sources

Multi-scale imaging at the diamond beamline I13 [PDF]

AIP Conference Proceedings, 2019
The I13 imaging and coherence beamline aims for multiscale imaging in the energy range of 6-30keV. The achievable resolution ranges from several microns to tens of nanometers. Several experimental methods are available on two independently operating branchlines.
Christoph Rau, Malte Storm, Shashidhara Marathe, Andrew J. Bodey, Silvia Cipiccia, Darren Batey, Xiaowen Shi, Marie-Christine Zdora, Irene Zanette   +8 more
openaire   +2 more sources

Coherence Branch at I13, DLS: The Multiscale, Multimodal, Ptycho-tomographic End Station [PDF]

Microscopy and Microanalysis, 2018
We present here a multiscale, multimodal, end station at the Coherence Branch, I13, at the Diamond Light Source (DLS). The core modality of the beamline is x-ray ptychography [1], which combines coherent diffraction imaging (CDI) with scanning ...
D. Batey, S. Cipiccia, X. Shi, S. Williams, K. Wanelik, A. Wilson, S. Pérez-Tamarit, P. Cimavilla, M. A. Ródriguez-Pérez, C. Rau   +9 more
openaire   +2 more sources

Ptychotomography at DLS Coherence Beamline I13

Journal of Physics: Conference Series, 2017
We describe the implementation and execution of ptychotomography at I13-1, the coherence branchline at Diamond Light Source. The data collection and image reconstruction protocol is demonstrated with the three dimensional reconstruction of a nanoporous gold sample.
V. S. C. Kuppili, S. Sala, S. Chalkidis, A. M. Wise, A. D. Parsons, I. Zanette, C. Rau, P. Thibault   +7 more
openaire   +3 more sources

Formation of the Most Iodine‐Rich Polyiodide [I13]− in Pore‐Partitioned Metal‐Organic Frameworks for Efficient Iodine Capture

Aggregate
Radioactive iodine produced from nuclear fission in power plants presents substantial environmental risks and requires effective remediation measures. Metal‐organic frameworks (MOFs) containing specifically designed pore geometries with stable skeletons ...
Feng-Yu Chen, Xin-Xin Lu, Yu-Hui Luo, Jie Li, Dongen Zhang, Yong Yan   +5 more
semanticscholar   +2 more sources

Multi-Scale Imaging at the Coherence and Imaging Beamline I13 at Diamond [PDF]

Microscopy and Microanalysis, 2018
The Diamond I13 imaging and coherence beamline performs multiscale imaging and tomography with phase sensitive imaging methods. Operating in the energy range of 6-30keV, the achievable resolution ranges from several microns to tens of nanometers [1,2].
Rau, Christoph, Storm, Malte, Marathe, Shashidhara, Bodey, Andrew J, Cipiccia, Silvia, Batey, Darren, Shi, Xiaowen, Zdora, Marie-Christine, Zanette, Irene, Perez-Tamarit, Saul, Cimavilla, Paula, Rodriguez-Perez, Miguel A., Doring, Florian, David, Christian   +13 more
openaire   +4 more sources