Results 121 to 130 of about 35,093 (269)

BIEN: A biodiversity informatics ecosystem advancing open and reproducible workflows for plant observation, plot and trait data

open access: yesMethods in Ecology and Evolution, EarlyView.
Abstract The rapid expansion of biodiversity data presents new opportunities to understand and forecast biosphere dynamics. However, disparate and dispersed data, taxonomic and geographic inconsistencies, pervasive quality issues, and a lack of reproducable workflows hinder synthesis, introduce biases and limit accurate assessment of biodiversity ...
Brian J. Enquist   +38 more
wiley   +1 more source

Sodium butyrate ameliorates renal tubular lipid accumulation through a protein phosphatase 2A/transcription factor EB axis in diabetic nephropathy

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Extensive evidence indicates that lipid accumulation causes renal tubular injury, which further contributes to diabetic nephropathy (DN) progression. Short‐chain fatty acids (SCFAs) play an important role in the maintenance of cellular metabolic health.
Jiayin Tao   +12 more
wiley   +1 more source

Weekly, monthly and seasonal rainfall at Bengaluru in Karnataka

open access: yesJournal of Agrometeorology, 2010
B.T. RAVINDRABABU   +3 more
doaj   +1 more source

A Critical Review of the 2025 RSHE Guidance and Alternative Approach Framed in Safe Uncertainty

open access: yesChildren &Society, EarlyView.
ABSTRACT This policy review critically examines the English government's 2025 statutory guidance on Relationships Education, Relationship and Sex Education and Health Education (RSHE), analysing its educational assumptions, strengths and limitations through the lens of safe uncertainty.
Emily Setty, Jonny Hunt
wiley   +1 more source

Heat Stress Triggers Nuclear Invagination and Spatial Compartmentalization of Protein Metabolism

open access: yesCell Proliferation, EarlyView.
Cells adapt heat stress to shape a nuclear invagination region function as “protein metabolism hotspots”, where both protein production and degradation are enhanced. ABSTRACT Heat stress is a common challenge for cells, causing multiple types of cellular damage while triggering complex stress responses, including the highly conserved mechanism known as
Zhi‐Hao Zhang   +11 more
wiley   +1 more source

Impact of screening programmes for type 1 diabetes in youth: A systematic review and meta‐analysis

open access: yesDiabetic Medicine, EarlyView.
Abstract Aim To evaluate the impact of anti‐islet antibody (IAb) screening on the general population and first‐degree relatives (FDRs)/high‐risk individuals and evidence‐based follow‐up modalities. Methods We performed this review through systematic searches of PubMed, EMBASE, Cochrane Library, Web of Science, ClinicalTrials.gov and International ...
Roberto Franceschi   +24 more
wiley   +1 more source

Teplizumab in Stage 2 Type 1 Diabetes: Clinical Practice Experience on Feasibility in 3 Adult Patients

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aim To describe the first Italian experience with teplizumab administered under a compassionate use programme for adults with Stage 2 type 1 diabetes (T1D), and to evaluate its feasibility, safety and early metabolic outcomes in a real‐life clinical setting outside formal clinical trials.
V. Guarnotta   +6 more
wiley   +1 more source

Renewable energy provisioning for ICT services in a future internet [PDF]

open access: yes, 2011
Cheriet, Mohamed   +8 more
core   +1 more source

The Risk of Disease Progression of Type 1 Diabetes in First‐Degree Relatives of People With Type 1 Diabetes: Design and Rationale of a Prospective, Longitudinal Study in China

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims In China, information on individuals who test positive for islet autoantibodies (IAb), including single IAb‐positive individuals and those with early‐stage Type 1 diabetes (T1D), and their risk of progression to Stage 3 T1D is limited. The goal of this study is to assess the risk of progression to T1D in first‐degree relatives (FDRs) of ...
Lixin Guo   +14 more
wiley   +1 more source

Toward Personalized Medicine in Type 1 Diabetes: Understanding How Patient Heterogeneity Influences Therapeutic Efficacy

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Pharmacologic interventions for type 1 diabetes (T1D) have advanced significantly in recent years with the advent of the first FDA approved therapy teplizumab for delaying symptomatic disease onset in 2022. Despite this progress, major hurdles remain in moving toward personalized medicine approaches for T1D.
Jasmine Pipella, Peter J. Thompson
wiley   +1 more source

Home - About - Disclaimer - Privacy