Results 121 to 130 of about 3,629 (264)

Economic Power of Political Leaders: Evidence From Central Leaders' Local Tours in China

open access: yesThe Developing Economies, EarlyView.
ABSTRACT Do political leaders play a role in shaping economic outcomes? Can we quantify and compare the economic influence of contemporary political leaders? This paper examines the economic impact of autocratic leadership through the lens of firm visits in China, offering a unique empirical strategy to assess their influence.
Asei Ito, Jaehwan Lim, Hongyong Zhang
wiley   +1 more source

Understanding parents' perspectives of repeated blinded continuous glucose monitoring in children with early‐stage type 1 diabetes and an affected first‐degree relative

open access: yesDiabetic Medicine, EarlyView.
Abstract Aim To explore the lived experiences of parents of children at risk of type 1 diabetes (T1D) undergoing repeated blinded continuous glucose monitoring (CGM). Method Since 2021, children with persistent islet autoimmunity in the Environmental Determinants of Islet Autoimmunity (ENDIA) study have been invited to participate in a sub‐study ...
Alexandra S. Tully   +15 more
wiley   +1 more source

Diagnosis and Management of Adult Type 1 Diabetes Mellitus: Systematic Reviews of Biomarkers, Insulin Regimens and Insulin Delivery Devices Highlighting Evidence Gaps in Emergency and Humanitarian Settings

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims Supporting the World Health Organization's (WHO) 2021 Global Diabetes Compact's goals, we conducted three systematic reviews on type 1 diabetes (T1D) in adults concerning (1) diagnostic biomarkers, (2) insulin regimens and (3) insulin delivery devices, focusing on emergency and humanitarian settings.
Niyati Patwa   +10 more
wiley   +1 more source

Unraveling in vitro phase separation and aggregation properties of the structured region of FMRP and the impact of Fragile X syndrome‐linked mutations

open access: yesThe FEBS Journal, EarlyView.
Fragile X messenger ribonucleoprotein 1 (FMRP) is a multidomain RNA‐binding protein associated with Fragile X Syndrome (FXS). We found that its N‐terminal structured region has an intrinsic propensity to undergo liquid–liquid phase separation and fibril formation. FXS‐associated mutations perturb protein stability and aggregation propensity, suggesting
Flavia Catalano   +10 more
wiley   +1 more source

Physiological media and oxygen levels modulate cancer hallmarks in cultured breast cancer cells

open access: yesThe FEBS Journal, EarlyView.
MCF7 breast cancer cells were cultured in standard conditions (18% O2 and DMEM) and physiological conditions (5% O2 and Plasmax, a medium modeled after the human plasma metabolome). A combined transcriptomic and proteomic approach was used to identify gene expression signatures at the mRNA and protein levels upstream of functional enrichment analyses ...
Jacob E. Wiebe   +5 more
wiley   +1 more source

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