Objective The purpose of this study was to determine the benefit of a behaviorally designed incentive program and glucocorticoid injections in reducing symptoms and promoting physical activity in patients with knee osteoarthritis (KOA). Methods This was a pragmatic, multisite, factorially designed, blinded, randomized clinical trial.
Joshua F. Baker +17 more
wiley +1 more source
Objective Disease activity plays a central role in rheumatoid arthritis (RA) clinical studies. The inconsistent availability of data on disease activity in real‐world electronic health records (EHR) data has limited the ability to generate real‐world evidence (RWE). This study aimed to develop and validate scalable machine learning (ML) models to infer
David Cheng +34 more
wiley +1 more source
Essential and toxic elements intake from botanical extracts: a probabilistic risk-benefit evaluation within the Italian dietary context. [PDF]
Lanza GT +5 more
europepmc +1 more source
Clock genes regulate Ca2+ signaling and mitochondrial bioenergetics to inhibit Sjogren's disease
Objective Although Ca2+ signaling and metabolism have been identified as key determinants for the development of Sjogren's disease (SjD), the intricate connection between them and salivary gland physiology remains poorly understood. Methods Fluorescence‐based Ca2+ imaging, RNA seq, and mitochondrial activity were used to investigate the effects of ...
Viktor R. Drel +12 more
wiley +1 more source
Surgical approach to intraabdominal sepsis: a damage control approach can reduce stoma rates. [PDF]
Smet H, Hirt J, Hahnloser D, Grass F.
europepmc +1 more source
Abstract This paper is a systematic literature review (SLR) of research published between 2009 and 2022 that aims to identify facilitators and barriers to implementing staff development projects (SDPs) in schools in England. Twelve research papers fulfilled all inclusion criteria and were each evaluated as being at least medium‐quality research.
David Preston +2 more
wiley +1 more source
Antibodies and distortion of insulin and C-peptide results in patients with hypoglycaemia of unknown origin. [PDF]
Ismail AAA.
europepmc +1 more source
Arsenic Species and Nitrogen Stable Isotope Ratios in the Japanese Diet-Dietary Markers of Seafood. [PDF]
Yoshinaga J, Narukawa T.
europepmc +1 more source
Transseptal Puncture for Left Atrial Appendage Closure: A Consensus Document From the Second European Left Atrial Appendage Club. [PDF]
Rosseel L +11 more
europepmc +1 more source
Overcoming barriers, driving progress: Clinical science at IAS 2025. [PDF]
Cordova E +3 more
europepmc +1 more source

