Results 171 to 180 of about 3,936,245 (245)

Click'n ROPISA: One‐Pot Synthesis of Ultrabright Fluorescent Nanoparticles Made of Polypeptides

Angewandte Chemie, EarlyView.
Self‐assembly and fluorophore conjugation proceed rapidly in a one‐pot “Click'n ROPISA” process, yielding intensely fluorescent polypeptide nanoparticles with tunable visible emission. High dye loading enables efficient energy transfer and single‐particle visualization, while the straightforward synthesis provides versatile access to bright ...
Amin El Jarroudi Hammou, Juliette Lavainne, Rohit Mangalwedhekar, Jyothis Devasia, Laurent Cognet, Sébastien Lecommandoux, Colin Bonduelle, Chloé Grazon   +7 more
wiley   +2 more sources

Conservation Planning and Reporting Implications of qPCR-based Multi-species eDNA Detection Under EU Environmental Regulations. [PDF]

Environ Manage
Giovacchini S, Mirone E, Bruno A, Ramazzotti F, Caprotti L, Monaco P, Di Febbraro M, Manfrin C, Jamwal PS, Belluardo F, Galimberti A, Loy A.   +11 more
europepmc   +1 more source

The Role of Glutamatergic and Dopaminergic Genes in Resistant Schizophrenia: A Systematic Review

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT Psychosis is a heterogeneous disorder, with approximately one‐third of patients experiencing treatment resistance, predominantly among individuals diagnosed with Schizophrenia. Treatment‐resistant schizophrenia (TRS) may stem from a distinct biological signature, involving abnormalities in the dopaminergic and glutamatergic systems.
Maria Teresa Moreno‐Calle, Silvia Iñiguez‐Barrio, Maria Aurora Arrue, Leire Erkoreka   +3 more
wiley   +1 more source

Beyond Nature's Blueprint: Macrocyclic Peptides Containing Unnatural Amino Acids in Therapeutic Development

Angewandte Chemie, EarlyView.
Strategic incorporation of unnatural amino acids transforms macrocyclic peptides into drug‐like molecules capable of engaging challenging targets. These building blocks enhance stability, permeability, and bioavailability, accelerating the development of next‐generation peptide therapeutics.
Krishna K. Sharma, Komal Sharma, Anku Sharma, Kamya Rao, Rahul Jain, Brett VanVeller   +5 more
wiley   +2 more sources

SATB2 dysregulation generates a novel circular RNA and drives KRAS-like transcriptional reprogramming and transformation-associated phenotypes. [PDF]

Cell Commun Signal
Eleazer R, George S, Shoemaker LJ, Saintilnord WN, Cassidy RN, Pyman A, Lau K, Soper-Hopper MT, Lee H, Chandler DP, Fondufe-Mittendorf YN.   +10 more
europepmc   +1 more source

Modeling Catheter‐Associated Bladder Mucosal Adhesion and Microtrauma Using a Human Urothelial Microtissue Model

Advanced NanoBiomed Research, EarlyView.
Intermittent catheter use can damage the urinary tract and predispose to infection. We deployed a complex human urothelial model to investigate. Catheter contact induced compressive and shear stress causing umbrella cell disruption, reduced barrier function, inflammation and increased cell adhesion to the catheter surface.
Nazila V. Jafari, Jennifer L. Rohn
wiley   +1 more source

[O─I─O]+ Halogen‐Bonded Complexes of Pyridine N‐Oxides

Angewandte Chemie, EarlyView.
The missing puzzle of 3‐center‐4‐electron halogen‐bonded complexes viz. [O─I─O]+ of pyridine N‐oxides are structurally characterized by x‐ray diffraction. Monodentate N‐oxide O‐atom acts as the halogen bond acceptor. Their solution complexations are characterized by 15N NMR spectroscopy.
Rakesh Puttreddy, Sergi Burguera, Antonio Frontera, Kari Rissanen   +3 more
wiley   +2 more sources

Green Analytical Workflows: Recent Advances in Sample Preparation and Instrumental Analysis of Food Contact Materials. [PDF]

Molecules
Cortesi L, Riboni N, Facchini C, Bianchi F.   +3 more
europepmc   +1 more source

Short Sb···Sb Contacts in Polymorphic Tris(p‐Tolyl)Antimony: A Hallmark of Organoantimony(III) Solid‐State Chemistry?

Angewandte Chemie, EarlyView.
Discovery of polymorphism in solid tris(p‐tolyl)antimony(III) highlighted short, direct antimony‐antimony contacts, with interatomic separation shorter than the sum of the van der Waals radii, and calculated interaction energy of ca. 26 kJ mol−1 that includes a significant dispersion component.
Imogen Suh, Michael Ferguson, Filip Topić, Fu‐Qiang Gong, Mihails Arhangelskis, Hatem M. Titi, D. Scott Bohle, Vinko Nemec, Levente Kiss, Andrew J. Morris, Cristian Silvestru, Dominik Cinčić, Tomislav Friščić   +12 more
wiley   +2 more sources

Amaryllidaceae Alkaloids and Isoquinoline Alkaloids: A Perspective on Historical Approaches to Pathway Elucidation. [PDF]

Plants (Basel)
Peña-Morales M, Vega-Páez JD, Cortes N, Osorio E, Caicedo PA, Barrera-Ocampo A, Álvarez O, Gonzáles Barrios AF, Villegas-Torres MF.   +8 more
europepmc   +1 more source