Results 171 to 180 of about 267,460 (304)

Multimodal Image Guidance in Subthalamic Deep Brain Stimulation for Parkinson's Disease

open access: yesAnnals of Neurology, EarlyView.
Objective Accurate electrode placement and individual stimulation parameters influence the outcomes of subthalamic deep brain stimulation in Parkinson's disease. Neuroimaging‐based models can help evaluate how electrode placement impacts improvement, aiming to reduce the burden of programming.
Patricia Zvarova   +27 more
wiley   +1 more source

Nonviral Gold Nanoparticle‐Mediated Delivery of CRISPR‐Cas9 Ribonucleoprotein and Long DNA Transgenes Into Primary Blood Cells

open access: yesAdvanced NanoBiomed Research, EarlyView.
CRISPR/Cas9 has revolutionized the field of gene therapy, but delivery remains an outstanding issue. We propose a nonviral gold‐nanoparticle platform for co‐delivery of CRISPR/Cas9 ribonucleoprotein and long 2.1 kilobase dsDNA transgene constructs. This CRISPR‐AuNP is inexpensive to produce and mediate gene editing and DNA delivery in T cells and CD34+
Rachel A. Cunningham   +8 more
wiley   +1 more source

Low Toe-Brachial Indices are Associated with Saccular Intracranial Aneurysms. [PDF]

open access: yesVasc Health Risk Manag
Kangas E   +12 more
europepmc   +1 more source

Финансовая аренда в финансовой отчетности арендаторов в соответствии с IAS 17 «Аренда»

open access: yesМеждународный бухгалтерский учет, 2011
В статье приводится понятие финансовой аренды, порядок признания финансовой аренды у арендатора и ее раскрытия в финансовой отчетности арендатора в соответствии с международным стандартом, а также расчет распределения процентных платежей по финансовой аренде и амортизационных отчислений по арендуемым активам.
openaire   +1 more source

Multi‐Responsive Bowl‐Shaped Janus Nanomotors Based on Polyitaconic acid/Polypyrrole on the Surface of Iron Oxide Nanoparticles with Chemical, Electrical, and Magnetic Field Actuation for Targeted Drug Delivery Applications

open access: yesAdvanced NanoBiomed Research, EarlyView.
Bowl‐shaped Janus nanomotors with platinum, iron oxide, and polypyrrole integrate catalytic, magnetic, and electric propulsion for targeted drug delivery. They demonstrate controlled, directional motion under varying pH and hydrogen peroxide conditions, with optimal performance in neutral media.
Kimia Tavakoli Dehaghi   +3 more
wiley   +1 more source

A cost‐effective DNA extraction protocol for long‐read sequencing in non‐model plants

open access: yesApplications in Plant Sciences, EarlyView.
Abstract Premise Third‐generation sequencing has revolutionized genomics, enabling in‐depth analysis of genome sequence, structure, and epigenetic features. Yet, extracting high‐quality DNA for long‐read sequencing remains a bottleneck—particularly in non‐model plants, such as mature trees growing in natural environments, which often contain abundant ...
Sofia Gaischuk   +6 more
wiley   +1 more source

IAS 17 -standardin käyttöönoton vaikutukset toimintaedellytysten arviointiin pienissä ja keskisuurissa yrityksissä

open access: yes, 2009
Tutkielma käsittelee IAS 17 -standardin käyttöönoton vaikutuksia pienten ja keskisuurten yritysten toimintaedellytyksiin. Tutkielma toteutetaan Suomen kirjanpitolain ja IAS 17 -standardin kirjaustapaerojen vaikutuksien tutkimisella yrityksen tilinpäätöksestä laskettaviin tunnuslukuihin.
openaire   +1 more source

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