Results 221 to 230 of about 267,142 (281)

Population pharmacokinetics and exposure–response analysis of durvalumab in patients with resectable stage II to IIIB (N2) NSCLC in the phase III AEGEAN study

British Journal of Clinical Pharmacology, EarlyView.
Aims In the AEGEAN study, perioperative durvalumab plus platinum‐based neoadjuvant chemotherapy for patients with resectable stage II to IIIB (N2) non‐small‐cell lung cancer (NSCLC) demonstrated a favourable benefit–risk profile. This study evaluated population pharmacokinetics (PopPK) and exposure–response (ER) relationships of durvalumab in patients ...
Xiaoying Zhao, Junjie Ding, Jiajia Zhao, Ling Zhang, Aburough Abegesah, Yu‐qian Zhang, Cathy O'Brien, Gary J. Doherty, Allen C. Chen, KyoungSoo Lim, Song Ren, Peiming Ma, Diansong Zhou   +12 more
wiley   +1 more source

[Subcutaneous defibrillator (S-ICD)]. [PDF]

Herz
Kuschyk J, Fastenrath F, Sattler K, Akin I, Duerschmied D, Rudic B.   +5 more
europepmc   +1 more source

A systematic review of facilitators and barriers to school staff development projects using the Consolidated Framework for Implementation Research

British Educational Research Journal, EarlyView.
Abstract This paper is a systematic literature review (SLR) of research published between 2009 and 2022 that aims to identify facilitators and barriers to implementing staff development projects (SDPs) in schools in England. Twelve research papers fulfilled all inclusion criteria and were each evaluated as being at least medium‐quality research.
David Preston, Pamela Qualter, Kevin Woods   +2 more
wiley   +1 more source

Macrophage migration inhibitory factor-CD74 axis drives vascular smooth muscle cell-induced M1 macrophage polarization to exacerbate intracranial aneurysm inflammation. [PDF]

Front Immunol
Chen Y, Huang JH, Wang QX, Song JH, Chen JN.   +4 more
europepmc   +1 more source

ANNEXES to the REPORT FROM THE COMMISSION TO THE EUROPEAN PARLIAMENT, THE COUNCIL AND THE EUROPEAN COURT OF AUDITORS 2015 Annual Management and Performance Report for the EU Budget. COM (2016) 446 final, ANNEXES 1 to 6, 5.7.2016 [PDF]

, 2016

core  

Impact of invasive weed Parthenium hysterophorus (Asteraceae) on mosquito abundance and plant-feeding behavior in an arboviral endemic region in Kenya. [PDF]

Parasit Vectors
Osman T, Chiuya T, Fèvre EM, Junglen S, Borgemeister C.   +4 more
europepmc   +1 more source

Improved Messenger RNA Stability and Biocompatibility Through Self‐Gelatinizable Nucleic Acids

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Recent advances in the chemical synthesis and modification of messenger RNA (mRNA) have generated growing interest in mRNA‐based therapeutics. However, the inherent instability of mRNA in vivo and during storage remains a major challenge, requiring the development of safe and effective delivery systems.
Takumi Tanifuji, Kosuke Kusamori, Chihiro Tanaka, Hideki Sakai, Shoko Itakura, Makiya Nishikawa   +5 more
wiley   +1 more source

Development and validation of a prediction model for in-hospital mortality in patients with intra-abdominal sepsis: a dual-database study using MIMIC-IV and eICU databases. [PDF]

BMJ Open
Zhang J, Chen Y, Zhao CC, Wang J, Hu ZJ.
europepmc   +1 more source

Radial capacity and hemodynamics evaluation in vitro and implantable feasibility validation in vivo of thinner bioresorbable polymer vascular stents

BMEMat, EarlyView.
A series of in vitro experiments, numerical simulations and in vivo experiments were conducted to jointly evaluate the effects of different thicknesses of bioabsorbable polymer vascular stents on their radial capacity, hemodynamics and in vivo outcomes.
Chong Chen, Tao Li, Zhongyou Li, Jingyuan Zhou, Zhuo Zhang, Yan Xiong, Rifang Luo, Yu Chen, Yunbing Wang, Ping Fu   +9 more
wiley   +1 more source

Robot-assisted frame screws placement for the surgical management of complex acetabular fractures: a single-center retrospective study. [PDF]

BMC Musculoskelet Disord
Chen J, Huang G, Yu K, Sun W, Tang L, Xue P, Guo X, Chen K.   +7 more
europepmc   +1 more source