Results 51 to 60 of about 267,460 (304)

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Reanalysis and reclassification of rare genetic variants associated with inherited arrhythmogenic syndromes [PDF]

open access: yes, 2020
Background: Accurate interpretation of rare genetic variants is a challenge for clinical translation. Updates in recommendations for rare variant classification require the reanalysis and reclassification.
Abou Tayoun   +27 more
core   +1 more source

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

open access: yesFEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart   +7 more
wiley   +1 more source

Information adequacy of medicine package inserts in India: A critical evaluation

open access: yesPerspectives in Clinical Research, 2021
Objectives: Package inserts (PIs) are used by physicians and other health-care providers as ready source of approved prescribing information. In India, they are subject to statutory regulations that specify the information to be provided under various ...
Bikramjit Barkondaj   +5 more
doaj   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

open access: yesFEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake   +4 more
wiley   +1 more source

INFOFI CAC 40 [PDF]

open access: yes, 2014
La Profession Comptable présente la première édition de Infofi CAC 40. Cette étude présente sur 5 thématiques IFRS la norme dans sa plus récente actualité et les pratiques les plus pertinentes des groupes du CAC 40 sous la forme d’extraits de leurs ...
L. Escaffre
core   +1 more source

Even Dimensional Improper Affine Spheres [PDF]

open access: yes, 2014
There are exactly two different types of bi-dimensional improper affine spheres: the non-convex ones can be modeled by the center-chord transform of a pair of planar curves while the convex ones can be modeled by a holomorphic map. In this paper, we show
Craizer, Marcos   +2 more
core   +2 more sources

Abstract Number ‐ 126: Use of Woven EndoBridge device for Aneurysms in Off‐Labeled Locations: Systematic Review and Meta‐Analysis

open access: yesStroke: Vascular and Interventional Neurology, 2023
Introduction The Woven EndoBridge (WEB) device was originally approved to treat intracranial wide‐necked saccular bifurcation aneurysms. Recent studies have suggested its use for the treatment of intracranial aneurysms (IA) in alternative locations with ...
Aaron Rodriguez‐Calienes   +12 more
doaj   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

open access: yesAging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel   +4 more
wiley   +1 more source

Unisel tumpuan tokoh akademik sains Islam sedunia [PDF]

open access: yes, 2009
SHAH ALAM : Universiti Selangor (Unisel) yang meraikan ulang tahun ke-10 hari ini melangkah gagah ke arena akademik antarabangsa apabila terpilih sebagai penganjur dan tuan rumah Persidangan Perhimpunan Agong Sains Akademi Sains Dunia Islam (IAS) tahunan
Berita Harian,
core  

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