Results 171 to 180 of about 10,417 (244)

The β integrin modulates serotonin sensitivity via NPxY motifs to regulate egg laying and mechanosensation behaviors in Caenorhabditis elegans

Developmental Dynamics, EarlyView.
Abstract Background Integrin is an αβ heterodimeric receptor to the extracellular matrix; its binding to the matrix recruits focal adhesions to two NPxY motifs, the tyrosine phosphorylation sites in the cytoplasmic domain. Studies found that replacing tyrosines (Y) with phenylalanines (F) in the motif of β1 integrin displayed little developmental or ...
Josh Haram Bumm, Daniel Dogeon Lee, Zhongqiang Qiu, Angela Haeun Choi, Meghana Kolluri, Michael J. Olsen, Lianzijun Wang, Myeongwoo Lee   +7 more
wiley   +1 more source

Evaluation of Knowledge and Anxiety Levels in Caregivers of Children With Heart Disease Before and After Basic Life Support Training: A Preliminary Study. [PDF]

Cureus
Dabrowska A, Palczynski P, Meyer-Szary J, Jakitowicz K, Siemiński M, Kusmierz Z, Kwiatkowska J.   +6 more
europepmc   +1 more source

Fhod3 in zebrafish supports myofibril stability during growth of embryonic skeletal muscle

Developmental Dynamics, EarlyView.
Abstract Background Actin filament organization in cardiomyocytes critically depends on the formin Fhod3, but a role for Fhod3 in skeletal muscle development has not yet been described. Results We demonstrate here that in zebrafish mutated for one of two fhod3 paralog genes, fhod3a, skeletal muscle of the trunk appears normal through 2 days post ...
Aubrie Russell, Tracy Eng, Jeffrey D. Amack, David Pruyne   +3 more
wiley   +1 more source

Compartmental immunity in intra-abdominal infection: from peritoneal defense to systemic sepsis. [PDF]

Front Immunol
Wang X, Yu X, Chen Z, Chang Y, Ma T.
europepmc   +1 more source

Differential sensitivity to SHH signaling and neural crest‐mediated Gas1 expression regulate jaw size during development and evolution

Developmental Dynamics, EarlyView.
Abstract Background Developmental control of jaw size is crucial to prevent birth defects and facilitate evolutionary adaptation. We have shown that jaw size is established by neural crest mesenchyme (NCM), which are progenitor cells that migrate into the mandibular primordia and produce the jaws.
Zuzana Vavrušová, Daniel B. Chu, An Nguyen, Yeniko Ta, Jennifer L. Fish, Richard A. Schneider   +5 more
wiley   +1 more source

The influence of self-supporting personality on social anxiety in college students: the serial-mediating roles of attention bias and social problem-solving orientation. [PDF]

BMC Psychol
Weiyi W, Peibo W, Jing S.
europepmc   +1 more source

Implementation of guideline‐recommended medical therapy for patients with heart failure in Europe

ESC Heart Failure, Volume 12, Issue 2, Page 790-798, April 2025.
Abstract Physicians' adherence to guideline‐recommended heart failure (HF) treatment remains suboptimal, especially regarding the target doses. In particular, there is evidence that non‐cardiologists are less compliant with HF guideline recommendations. This is likely to have a detrimental impact on patients' survival, readmissions and quality of life.
Maurizio Volterrani, Petar Seferovic, Gianluigi Savarese, Ilaria Spoletini, Egidio Imbalzano, Antoni Bayes‐Genis, Ewa Jankowska, Michele Senni, Marco Metra, Ovidiu Chioncel, Andrew J. S. Coats, Giuseppe M. C. Rosano   +11 more
wiley   +1 more source

Change in faecal incontinence pattern after gastric bypass surgery: related to change in anal sphincter thickness? [PDF]

Int J Colorectal Dis
Wennerlund J, Thalén D, Östevind A, Gunnarsson U, Strigård K.   +4 more
europepmc   +1 more source

Influence of 6‐Trifluoromethyluracil Versus Chloride Counterions in the Properties of Bis‐(1,10‐Phenanthroline)chloridecopper(II) Motif: Spectroscopic and In Vitro Biological Activity Assays

European Journal of Inorganic Chemistry, EarlyView.
This work explores the influence of 6‐trifluoromethyluracil versus chloride counterions on the antibacterial and antitumoral activities of bis‐(1,10‐phenanthroline)chloridecopper(II) motif. The counterion modulates antibacterial potency and the identity of the dominant reactive species, while leaving DNA recognition by the shared cation essentially ...
Francisco Mastrobuono‐Cordeiro, Gabriele de M. Pereira, Douglas H. Nakahata, Stefano Scoditti, Fernanda V. P. de V. Azevedo, Letícia P. de Oliveira, Silmara C. L. Frajácomo, Javier Ellena, Pedro H. de O. Santiago, Daniel Reta, Gilberto C. Franchi, Wilton R. Lustri, Carmen S. P. Lima, Pedro P. Corbi, Raphael E. F. de Paiva   +14 more
wiley   +1 more source