Results 241 to 250 of about 390,111 (338)

Cardiovascular Exercise Drives Neuroprotection in a Mouse Model of Spinocerebellar Ataxia 1 Via Rescue of Aberrant Splicing

open access: yesAnnals of Neurology, EarlyView.
Objective Spinocerebellar ataxia 1 (SCA1) is a fatal hereditary neurodegenerative disorder with no approved therapies, and gene‐targeting strategies have thus far failed in clinical trials. Exercise remains the only intervention shown to provide clinical benefit in patients with spinocerebellar ataxias (SCAs), yet the underlying mechanisms remain ...
Isabel Soto   +12 more
wiley   +1 more source

Multi-session CBM-I for social anxiety: examining psychopathology, cognitive, neural, and psychophysiological effects in a randomized controlled trial. [PDF]

open access: yesTransl Psychiatry
Abado E   +11 more
europepmc   +1 more source

Outcomes of Revision UCL Repair With Internal Brace for Failure of Primary UCL Reconstruction in Professional and Collegiate Baseball Pitchers: A First Look. [PDF]

open access: yesOrthop J Sports Med
Richard GJ   +11 more
europepmc   +1 more source

Toward the Synthesis of Pestalustaine A: Structural Revision and Formation of Original Strained Tricyclic Architectures

open access: yesAngewandte Chemie, EarlyView.
Our synthetic endeavor toward the total synthesis of the reported unprecedented tricyclic skeleton of the sesquiterpene pestalustaine A allowed us to perform divergent cyclizations of a bicyclo[4.4.1]undec‐3‐ene into complex tricyclic architectures and to revise the structure of the natural product.
Wei Cao   +12 more
wiley   +1 more source

Phase Ib/II trial to evaluate the safety and efficacy of atezolizumab and bevacizumab as adjuvant therapy following carbon-ion radiotherapy in hepatocellular carcinoma (VANGUARD): study protocol. [PDF]

open access: yesBMJ Open
Koroki K   +33 more
europepmc   +1 more source

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