Results 51 to 60 of about 2,130 (186)

Mitochondrial dynamics in Parkinson's disease: a role for α-synuclein?

open access: yesDisease Models & Mechanisms, 2017
The distinctive pathological hallmarks of Parkinson's disease are the progressive death of dopaminergic neurons and the intracellular accumulation of Lewy bodies enriched in α-synuclein protein.
Victorio M. Pozo Devoto   +1 more
doaj   +1 more source

MET Gene Amplification and MET Receptor Activation Are Not Sufficient to Predict Efficacy of Combined MET and EGFR Inhibitors in EGFR TKI-Resistant NSCLC Cells [PDF]

open access: yes, 2015
Epidermal growth factor receptor (EGFR), member of the human epidermal growth factor receptor (HER) family, plays a critical role in regulating multiple cellular processes including proliferation, differentiation, cell migration and cell survival ...
Cardinali, Beatrice   +8 more
core   +3 more sources

EPSILON: an eQTL prioritization framework using similarity measures derived from local networks [PDF]

open access: yes, 2013
Motivation: When genomic data are associated with gene expression data, the resulting expression quantitative trait loci (eQTL) will likely span multiple genes.
Cloots, Lore   +4 more
core   +2 more sources

A behavioral tagging account of kinase contribution to memory formation after spaced aversive training

open access: yesiScience, 2023
Summary: Long-term memory (LTM) can be induced by repeated spaced training trials. Using the weak inhibitory avoidance (wIA) task, we showed that one wIA session does not lead to a 24-h LTM, whereas two identical wIA sessions spaced by 15 min to 6 h ...
Pablo Budriesi   +6 more
doaj   +1 more source

The history of WiMAX: a complete survey of the evolution in certification and standarization for IEEE 802.16 and WiMAX [PDF]

open access: yes, 2012
Most researchers are familiar with the technical features of WiMAX technology but the evolution that WiMAX went through, in terms of standardization and certification, is missing and unknown to most people.
Demeester, Piet   +3 more
core   +1 more source

GDNF/GFRα1 Complex Abrogates Self-Renewing Activity of Cortical Neural Precursors Inducing Their Differentiation

open access: yesStem Cell Reports, 2018
Summary: The balance between factors leading to proliferation and differentiation of cortical neural precursors (CNPs) determines the correct cortical development.
Antonela Bonafina   +3 more
doaj   +1 more source

Skyrmion crystals in the pseudo-spin-1/2 Bose-Einstein condensates

open access: yes, 2013
Exact two-dimensional solutions are constructed for the pseudo-spin-1/2 Bose-Einstein condensates which are described by the coupled nonlinear Gross-Pitaevskii equations where the intraspecies and interspecies coupling constants are assumed to be equal ...
Feng, Shiping   +3 more
core   +1 more source

Analysis of Population‐Level Avirulence and Virulence Genetic Frequencies Provides Insight Into Resistance Gene Rotation and Plant Disease Epidemiology

open access: yesPlant Pathology, Volume 74, Issue 4, Page 1055-1067, May 2025.
Our study uses high‐throughput sequencing to monitor avirulence gene frequencies within pathogen populations to show that rotation of plant resistance genes can impact pathogen populations. ABSTRACT Blackleg disease, caused by Leptosphaeria maculans, leads to significant yield losses to canola (Brassica napus) production worldwide. Whilst the impact of
Alec J. McCallum   +3 more
wiley   +1 more source

αSynuclein control of mitochondrial homeostasis in human-derived neurons is disrupted by mutations associated with Parkinson’s disease

open access: yesScientific Reports, 2017
The etiology of Parkinson’s disease (PD) converges on a common pathogenic pathway of mitochondrial defects in which α-Synuclein (αSyn) is thought to play a role.
Victorio Martin Pozo Devoto   +12 more
doaj   +1 more source

Constructing a no-reference H.264/AVC bitstream-based video quality metric using genetic programming-based symbolic regression [PDF]

open access: yes, 2013
In order to ensure optimal quality of experience toward end users during video streaming, automatic video quality assessment becomes an important field-of-interest to video service providers.
Demeester, Piet   +5 more
core   +1 more source

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