Results 211 to 220 of about 199,904 (291)

Bailout Guiding Catheter Exchange Using Medilizer: A Case Report. [PDF]

open access: yesJ Neuroendovasc Ther
Yamaguchi Y   +4 more
europepmc   +1 more source

Mechanisms underlying local Ca2+ signalling differences between right and left atrial myocytes at normal and increased frequencies

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Left atrial myocytes have TAT‐associated faster Ca2+ release but are more prone to maladaptation at higher frequencies due to weaker peripheral SR Ca2+ uptake and smaller trigger Ca2+ current. Abstract Changes in heart rate affect Ca2+ signalling and contractility in ventricular muscle, but the effects on atrial Ca2+ signalling ...
Joon‐Chul Kim   +6 more
wiley   +1 more source

Deciphering pro‐arrhythmogenic mechanisms of EPAC in human atrial cardiomyocytes

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend This study aimed to investigate the effect of exchange proteins directly activated by cAMP (EPAC) on the regulation of human atrial cardiomyocyte electrophysiology and their potential involvement in the onset of atrial fibrillation (AF).
Arthur Boileve   +11 more
wiley   +1 more source

Maximal exercise at high altitude does not exacerbate inflammation in the human brain

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend This study investigated arterial–internal jugular venous (IJV) exchange of cytokines in response to low‐intensity and maximal cycling exercise at sea level and following 6–8 days at 3800 m a.s.l. There was a shift towards net release of interleukin‐6 (IL‐6), interleukin‐8 (IL‐8), monocyte chemoattractant protein‐1 (MCP‐1) and ...
Hannah G. Caldwell   +11 more
wiley   +1 more source

The interplay between dynamic regulation of ion‐channel gating and trafficking in cardiac arrhythmogenesis

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Cardiac cellular electrophysiology is modulated by multiple factors, including temperature, extracellular K+, heart rate/pacing frequency, and drugs. These modulators can have distinct effects on ion‐channel gating and transcription/trafficking over time.
Stefan Meier   +3 more
wiley   +1 more source

Multiparametric cardiomyocyte profiling with single‐LED excitation reveals subtype‐specific electromechanical coupling in LQTS in vitro

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend In vitro profiling of cardiac excitation–contraction coupling by simultaneous optical recording of membrane voltage, intracellular calcium and contraction. Schematic of the single‐LED optical imaging setup enabling simultaneous acquisition of action potentials, calcium and contraction transients (top).
Aleksandr Khudiakov   +10 more
wiley   +1 more source

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